Identity
HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
APO-L,APOL,APOL-I,FSGS4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8542
MIM: 603743
HGNC: 618
Ensembl: ENSG00000100342
Variants:
dbSNP: 8542
ClinVar: 8542
TCGA: ENSG00000100342
COSMIC: APOL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37962879 | 2024 | Genome-Wide Polygenic Risk Score for CKD in Individuals with APOL1 High-Risk Genotypes. | 0 |
| 38143038 | 2024 | Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population. | 0 |
| 38190141 | 2024 | Evaluating ApoL1 Genetic Testing Policy Options for Transplant Centers: A Delphi Consensus Panel Project with Stakeholders. | 1 |
| 38227370 | 2024 | APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease. | 5 |
| 38263248 | 2024 | HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma. | 0 |
| 38355600 | 2024 | Apolipoprotein L1 (APOL1) renal risk variant-mediated podocyte cytotoxicity depends on African haplotype and surface expression. | 1 |
| 38360481 | 2024 | Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. | 0 |
| 38542298 | 2024 | IFI16 Is Indispensable for Promoting HIF-1α-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions. | 0 |
| 38714935 | 2024 | African ancestry-derived APOL1 risk genotypes show proximal epigenetic associations. | 0 |
| 38838223 | 2024 | Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease. | 0 |
| 37962879 | 2024 | Genome-Wide Polygenic Risk Score for CKD in Individuals with APOL1 High-Risk Genotypes. | 0 |
| 38143038 | 2024 | Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population. | 0 |
| 38190141 | 2024 | Evaluating ApoL1 Genetic Testing Policy Options for Transplant Centers: A Delphi Consensus Panel Project with Stakeholders. | 1 |
| 38227370 | 2024 | APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease. | 5 |
| 38263248 | 2024 | HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma. | 0 |
Citation
Dessen P
APOL1 (apolipoprotein L1)
Atlas Genet Cytogenet Oncol Haematol. 2012-06-01
Online version: http://atlasgeneticsoncology.org/gene/52740/apol1
