Atlas of Genetics and Cytogenetics in Oncology and Haematology


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APOO (apolipoprotein O)

Identity

Alias_namesFAM121B
family with sequence similarity 121B
Alias_symbol (synonym)MGC4825
My025
Mic23
MIC26
Other alias
HGNC (Hugo) APOO
LocusID (NCBI) 79135
Atlas_Id 54131
Location Xp22.11  [Link to chromosome band Xp22]
Location_base_pair Starts at 23833348 and ends at 23907940 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACOT9 (Xp22.11) / APOO (Xp22.11)APOO (Xp22.11) / APOO (Xp22.11)HPS5 (11p15.1) / APOO (Xp22.11)
ZFX (Xp22.11) / APOO (Xp22.11)ACOT9 Xp22.11 / APOO Xp22.11ZFX Xp22.11 / APOO Xp22.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOO   28727
Cards
Entrez_Gene (NCBI)APOO  79135  apolipoprotein O
AliasesFAM121B; MIC26; Mic23; My025
GeneCards (Weizmann)APOO
Ensembl hg19 (Hinxton)ENSG00000184831 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184831 [Gene_View]  chrX:23833348-23907940 [Contig_View]  APOO [Vega]
ICGC DataPortalENSG00000184831
TCGA cBioPortalAPOO
AceView (NCBI)APOO
Genatlas (Paris)APOO
WikiGenes79135
SOURCE (Princeton)APOO
Genetics Home Reference (NIH)APOO
Genomic and cartography
GoldenPath hg38 (UCSC)APOO  -     chrX:23833348-23907940 -  Xp22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOO  -     Xp22.11   [Description]    (hg19-Feb_2009)
EnsemblAPOO - Xp22.11 [CytoView hg19]  APOO - Xp22.11 [CytoView hg38]
Mapping of homologs : NCBIAPOO [Mapview hg19]  APOO [Mapview hg38]
OMIM300753   
Gene and transcription
Genbank (Entrez)AA410995 AF061264 AK311865 AY359114 BC002333
RefSeq transcript (Entrez)NM_024122
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOO
Cluster EST : UnigeneHs.495851 [ NCBI ]
CGAP (NCI)Hs.495851
Alternative Splicing GalleryENSG00000184831
Gene ExpressionAPOO [ NCBI-GEO ]   APOO [ EBI - ARRAY_EXPRESS ]   APOO [ SEEK ]   APOO [ MEM ]
Gene Expression Viewer (FireBrowse)APOO [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79135
GTEX Portal (Tissue expression)APOO
Human Protein AtlasENSG00000184831-APOO [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUR5
Splice isoforms : SwissVarQ9BUR5
PhosPhoSitePlusQ9BUR5
Domains : Interpro (EBI)MIC26/MIC27    MIC26/MIC27_animal   
Domain families : Pfam (Sanger)ApoO (PF09769)   
Domain families : Pfam (NCBI)pfam09769   
Conserved Domain (NCBI)APOO
DMDM Disease mutations79135
Blocks (Seattle)APOO
SuperfamilyQ9BUR5
Human Protein Atlas [tissue]ENSG00000184831-APOO [tissue]
Peptide AtlasQ9BUR5
HPRD06657
IPIIPI00042580   IPI00797546   IPI00843886   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUR5
IntAct (EBI)Q9BUR5
FunCoupENSG00000184831
BioGRIDAPOO
STRING (EMBL)APOO
ZODIACAPOO
Ontologies - Pathways
QuickGOQ9BUR5
Ontology : AmiGOGolgi membrane  protein binding  extracellular region  extracellular space  mitochondrion  endoplasmic reticulum membrane  cytosol  lipid transport  integral component of mitochondrial inner membrane  very-low-density lipoprotein particle  low-density lipoprotein particle  high-density lipoprotein particle  cristae formation  MICOS complex  
Ontology : EGO-EBIGolgi membrane  protein binding  extracellular region  extracellular space  mitochondrion  endoplasmic reticulum membrane  cytosol  lipid transport  integral component of mitochondrial inner membrane  very-low-density lipoprotein particle  low-density lipoprotein particle  high-density lipoprotein particle  cristae formation  MICOS complex  
NDEx NetworkAPOO
Atlas of Cancer Signalling NetworkAPOO
Wikipedia pathwaysAPOO
Orthology - Evolution
OrthoDB79135
GeneTree (enSembl)ENSG00000184831
Phylogenetic Trees/Animal Genes : TreeFamAPOO
HOVERGENQ9BUR5
HOGENOMQ9BUR5
Homologs : HomoloGeneAPOO
Homology/Alignments : Family Browser (UCSC)APOO
Gene fusions - Rearrangements
Fusion : MitelmanACOT9/APOO [Xp22.11/Xp22.11]  [t(X;X)(p22;p22)]  
Fusion : MitelmanHPS5/APOO [11p15.1/Xp22.11]  [t(X;11)(p22;p15)]  
Fusion : MitelmanZFX/APOO [Xp22.11/Xp22.11]  [t(X;X)(p22;p22)]  
Fusion: TCGA_MDACCACOT9 Xp22.11 APOO Xp22.11 BRCA
Fusion: TCGA_MDACCZFX Xp22.11 APOO Xp22.11 BRCA
Tumor Fusion PortalAPOO
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOO [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOO
dbVarAPOO
ClinVarAPOO
1000_GenomesAPOO 
Exome Variant ServerAPOO
ExAC (Exome Aggregation Consortium)ENSG00000184831
GNOMAD BrowserENSG00000184831
Genetic variants : HAPMAP79135
Genomic Variants (DGV)APOO [DGVbeta]
DECIPHERAPOO [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOO 
Mutations
ICGC Data PortalAPOO 
TCGA Data PortalAPOO 
Broad Tumor PortalAPOO
OASIS PortalAPOO [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOO  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOO
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch APOO
DgiDB (Drug Gene Interaction Database)APOO
DoCM (Curated mutations)APOO (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOO (select a term)
intoGenAPOO
Cancer3DAPOO(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300753   
Orphanet
DisGeNETAPOO
MedgenAPOO
Genetic Testing Registry APOO
NextProtQ9BUR5 [Medical]
TSGene79135
GENETestsAPOO
Target ValidationAPOO
Huge Navigator APOO [HugePedia]
snp3D : Map Gene to Disease79135
BioCentury BCIQAPOO
ClinGenAPOO
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79135
Chemical/Pharm GKB GenePA162376709
Clinical trialAPOO
Miscellaneous
canSAR (ICR)APOO (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOO
EVEXAPOO
GoPubMedAPOO
iHOPAPOO
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:24 CET 2017

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