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APOPT1 (apoptogenic 1, mitochondrial)

Identity

Alias_namesC14orf153
chromosome 14 open reading frame 153
apoptogenic 1
Alias_symbol (synonym)MGC2562
APOP-1
Other aliasAPOP
APOP1
HGNC (Hugo) APOPT1
LocusID (NCBI) 84334
Atlas_Id 60438
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 103562957 and ends at 103590899 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APOPT1 (14q32.33) / MARK3 (14q32.32)APOPT1 (14q32.33) / MOB3A (19p13.3)KLC1 (14q32.33) / APOPT1 (14q32.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOPT1   20492
Cards
Entrez_Gene (NCBI)APOPT1  84334  apoptogenic 1, mitochondrial
AliasesAPOP; APOP1; C14orf153
GeneCards (Weizmann)APOPT1
Ensembl hg19 (Hinxton)ENSG00000256053 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000256053 [Gene_View]  chr14:103562957-103590899 [Contig_View]  APOPT1 [Vega]
ICGC DataPortalENSG00000256053
TCGA cBioPortalAPOPT1
AceView (NCBI)APOPT1
Genatlas (Paris)APOPT1
WikiGenes84334
SOURCE (Princeton)APOPT1
Genetics Home Reference (NIH)APOPT1
Genomic and cartography
GoldenPath hg38 (UCSC)APOPT1  -     chr14:103562957-103590899 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOPT1  -     14q32.33   [Description]    (hg19-Feb_2009)
EnsemblAPOPT1 - 14q32.33 [CytoView hg19]  APOPT1 - 14q32.33 [CytoView hg38]
Mapping of homologs : NCBIAPOPT1 [Mapview hg19]  APOPT1 [Mapview hg38]
OMIM220110   616003   
Gene and transcription
Genbank (Entrez)AK223092 AK223103 BC007412 BF528062 BP204024
RefSeq transcript (Entrez)NM_001302652 NM_001302653 NM_001302654 NM_032374
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOPT1
Cluster EST : UnigeneHs.598441 [ NCBI ]
CGAP (NCI)Hs.598441
Alternative Splicing GalleryENSG00000256053
Gene ExpressionAPOPT1 [ NCBI-GEO ]   APOPT1 [ EBI - ARRAY_EXPRESS ]   APOPT1 [ SEEK ]   APOPT1 [ MEM ]
Gene Expression Viewer (FireBrowse)APOPT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84334
GTEX Portal (Tissue expression)APOPT1
Human Protein AtlasENSG00000256053-APOPT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96IL0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96IL0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96IL0
Splice isoforms : SwissVarQ96IL0
PhosPhoSitePlusQ96IL0
Domains : Interpro (EBI)UPF0671   
Domain families : Pfam (Sanger)DUF2315 (PF10231)   
Domain families : Pfam (NCBI)pfam10231   
Conserved Domain (NCBI)APOPT1
DMDM Disease mutations84334
Blocks (Seattle)APOPT1
SuperfamilyQ96IL0
Human Protein Atlas [tissue]ENSG00000256053-APOPT1 [tissue]
Peptide AtlasQ96IL0
HPRD12637
IPIIPI00063672   IPI00956585   IPI00956278   IPI00956606   IPI00956285   IPI00956248   IPI00956197   IPI00956542   IPI00956501   IPI00956746   IPI00956709   IPI00956615   IPI01025907   IPI00917632   IPI00956296   
Protein Interaction databases
DIP (DOE-UCLA)Q96IL0
IntAct (EBI)Q96IL0
FunCoupENSG00000256053
BioGRIDAPOPT1
STRING (EMBL)APOPT1
ZODIACAPOPT1
Ontologies - Pathways
QuickGOQ96IL0
Ontology : AmiGOmitochondrion  positive regulation of smooth muscle cell apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of release of cytochrome c from mitochondria  intrinsic apoptotic signaling pathway  
Ontology : EGO-EBImitochondrion  positive regulation of smooth muscle cell apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of release of cytochrome c from mitochondria  intrinsic apoptotic signaling pathway  
NDEx NetworkAPOPT1
Atlas of Cancer Signalling NetworkAPOPT1
Wikipedia pathwaysAPOPT1
Orthology - Evolution
OrthoDB84334
GeneTree (enSembl)ENSG00000256053
Phylogenetic Trees/Animal Genes : TreeFamAPOPT1
HOVERGENQ96IL0
HOGENOMQ96IL0
Homologs : HomoloGeneAPOPT1
Homology/Alignments : Family Browser (UCSC)APOPT1
Gene fusions - Rearrangements
Tumor Fusion PortalAPOPT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOPT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOPT1
dbVarAPOPT1
ClinVarAPOPT1
1000_GenomesAPOPT1 
Exome Variant ServerAPOPT1
ExAC (Exome Aggregation Consortium)ENSG00000256053
GNOMAD BrowserENSG00000256053
Genetic variants : HAPMAP84334
Genomic Variants (DGV)APOPT1 [DGVbeta]
DECIPHERAPOPT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOPT1 
Mutations
ICGC Data PortalAPOPT1 
TCGA Data PortalAPOPT1 
Broad Tumor PortalAPOPT1
OASIS PortalAPOPT1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDAPOPT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch APOPT1
DgiDB (Drug Gene Interaction Database)APOPT1
DoCM (Curated mutations)APOPT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOPT1 (select a term)
intoGenAPOPT1
Cancer3DAPOPT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM220110    616003   
Orphanet23337   
DisGeNETAPOPT1
MedgenAPOPT1
Genetic Testing Registry APOPT1
NextProtQ96IL0 [Medical]
TSGene84334
GENETestsAPOPT1
Target ValidationAPOPT1
Huge Navigator APOPT1 [HugePedia]
snp3D : Map Gene to Disease84334
BioCentury BCIQAPOPT1
ClinGenAPOPT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84334
Chemical/Pharm GKB GenePA134961925
Clinical trialAPOPT1
Miscellaneous
canSAR (ICR)APOPT1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOPT1
EVEXAPOPT1
GoPubMedAPOPT1
iHOPAPOPT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:29:13 CET 2017

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