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APRT (adenine phosphoribosyltransferase)

Identity

Alias (NCBI)AMP
APRTD
HGNC (Hugo) APRT
LocusID (NCBI) 353
Atlas_Id 47016
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 88809469 and ends at 88811928 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APRT (16q24.3) / APRT (16q24.3)PIEZO1 (16q24.3) / APRT (16q24.3)TMEM185A (Xq28) / APRT (16q24.3)
FAM38A APRT 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)APRT   626
Cards
Entrez_Gene (NCBI)APRT    adenine phosphoribosyltransferase
AliasesAMP; APRTD
GeneCards (Weizmann)APRT
Ensembl hg19 (Hinxton)ENSG00000198931 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198931 [Gene_View]  ENSG00000198931 [Sequence]  chr16:88809469-88811928 [Contig_View]  APRT [Vega]
ICGC DataPortalENSG00000198931
TCGA cBioPortalAPRT
AceView (NCBI)APRT
Genatlas (Paris)APRT
SOURCE (Princeton)APRT
Genetics Home Reference (NIH)APRT
Genomic and cartography
GoldenPath hg38 (UCSC)APRT  -     chr16:88809469-88811928 -  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APRT  -     16q24.3   [Description]    (hg19-Feb_2009)
GoldenPathAPRT - 16q24.3 [CytoView hg19]  APRT - 16q24.3 [CytoView hg38]
ImmunoBaseENSG00000198931
genome Data Viewer NCBIAPRT [Mapview hg19]  
OMIM102600   614723   
Gene and transcription
Genbank (Entrez)BC106894 BC106895 BC107151 BM423481 BM550173
RefSeq transcript (Entrez)NM_000485 NM_001030018
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APRT
Alternative Splicing GalleryENSG00000198931
Gene ExpressionAPRT [ NCBI-GEO ]   APRT [ EBI - ARRAY_EXPRESS ]   APRT [ SEEK ]   APRT [ MEM ]
Gene Expression Viewer (FireBrowse)APRT [ Firebrowse - Broad ]
GenevisibleExpression of APRT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)353
GTEX Portal (Tissue expression)APRT
Human Protein AtlasENSG00000198931-APRT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07741   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07741  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07741
Splice isoforms : SwissVarP07741
PhosPhoSitePlusP07741
Domaine pattern : Prosite (Expaxy)PUR_PYR_PR_TRANSFER (PS00103)   
Domains : Interpro (EBI)Ade_phspho_trans    PRibTrfase_dom    PRTase-like   
Domain families : Pfam (Sanger)Pribosyltran (PF00156)   
Domain families : Pfam (NCBI)pfam00156   
Conserved Domain (NCBI)APRT
Blocks (Seattle)APRT
PDB (RSDB)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
PDB Europe1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
PDB (PDBSum)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
PDB (IMB)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
Structural Biology KnowledgeBase1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
SCOP (Structural Classification of Proteins)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
CATH (Classification of proteins structures)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45    6FCH    6FCI    6FCL    6FD4    6FD5    6FD6    6HGP    6HGQ    6HGR    6HGS   
SuperfamilyP07741
Human Protein Atlas [tissue]ENSG00000198931-APRT [tissue]
Peptide AtlasP07741
HPRD00029
IPIIPI00218693   IPI00816267   IPI00642457   
Protein Interaction databases
DIP (DOE-UCLA)P07741
IntAct (EBI)P07741
BioGRIDAPRT
STRING (EMBL)APRT
ZODIACAPRT
Ontologies - Pathways
QuickGOP07741
Ontology : AmiGOadenine binding  adenine phosphoribosyltransferase activity  protein binding  extracellular region  nucleoplasm  cytoplasm  cytoplasm  cytosol  cytosol  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  AMP binding  cellular response to insulin stimulus  secretory granule lumen  purine-containing compound salvage  neutrophil degranulation  AMP salvage  AMP salvage  extracellular exosome  
Ontology : EGO-EBIadenine binding  adenine phosphoribosyltransferase activity  protein binding  extracellular region  nucleoplasm  cytoplasm  cytoplasm  cytosol  cytosol  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  AMP binding  cellular response to insulin stimulus  secretory granule lumen  purine-containing compound salvage  neutrophil degranulation  AMP salvage  AMP salvage  extracellular exosome  
Pathways : KEGGPurine metabolism   
NDEx NetworkAPRT
Atlas of Cancer Signalling NetworkAPRT
Wikipedia pathwaysAPRT
Orthology - Evolution
OrthoDB353
GeneTree (enSembl)ENSG00000198931
Phylogenetic Trees/Animal Genes : TreeFamAPRT
HOGENOMP07741
Homologs : HomoloGeneAPRT
Homology/Alignments : Family Browser (UCSC)APRT
Gene fusions - Rearrangements
Fusion : MitelmanPIEZO1/APRT [16q24.3/16q24.3]  
Fusion PortalFAM38A APRT 16q24.3 BRCA
Fusion : QuiverAPRT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPRT [hg38]
dbVarAPRT
ClinVarAPRT
MonarchAPRT
1000_GenomesAPRT 
Exome Variant ServerAPRT
GNOMAD BrowserENSG00000198931
Varsome BrowserAPRT
Genomic Variants (DGV)APRT [DGVbeta]
DECIPHERAPRT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPRT 
Mutations
ICGC Data PortalAPRT 
TCGA Data PortalAPRT 
Broad Tumor PortalAPRT
OASIS PortalAPRT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPRT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAPRT
Mutations and Diseases : HGMDAPRT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APRT
DgiDB (Drug Gene Interaction Database)APRT
DoCM (Curated mutations)APRT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APRT (select a term)
intoGenAPRT
Cancer3DAPRT(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM102600    614723   
Orphanet775   
DisGeNETAPRT
MedgenAPRT
Genetic Testing Registry APRT
NextProtP07741 [Medical]
GENETestsAPRT
Target ValidationAPRT
Huge Navigator APRT [HugePedia]
ClinGenAPRT
Clinical trials, drugs, therapy
MyCancerGenomeAPRT
Protein Interactions : CTD
Pharm GKB GenePA24914
PharosP07741
Clinical trialAPRT
Miscellaneous
canSAR (ICR)APRT (select the gene name)
HarmonizomeAPRT
DataMed IndexAPRT
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAPRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:11:19 CET 2021
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