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APRT (adenine phosphoribosyltransferase)

Identity

Other namesAMP
APRTD
HGNC (Hugo) APRT
LocusID (NCBI) 353
Atlas_Id 47016
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 88875877 and ends at 88878342 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
APRT (16q24.3) / APRT (16q24.3)PIEZO1 (16q24.3) / APRT (16q24.3)TMEM185A (Xq28) / APRT (16q24.3)
FAM38A APRT 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APRT   626
Cards
Entrez_Gene (NCBI)APRT  353  adenine phosphoribosyltransferase
AliasesAMP; APRTD
GeneCards (Weizmann)APRT
Ensembl hg19 (Hinxton)ENSG00000198931 [Gene_View]  chr16:88875877-88878342 [Contig_View]  APRT [Vega]
Ensembl hg38 (Hinxton)ENSG00000198931 [Gene_View]  chr16:88875877-88878342 [Contig_View]  APRT [Vega]
ICGC DataPortalENSG00000198931
TCGA cBioPortalAPRT
AceView (NCBI)APRT
Genatlas (Paris)APRT
WikiGenes353
SOURCE (Princeton)APRT
Genomic and cartography
GoldenPath hg19 (UCSC)APRT  -     chr16:88875877-88878342 -  16q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APRT  -     16q24.3   [Description]    (hg38-Dec_2013)
EnsemblAPRT - 16q24.3 [CytoView hg19]  APRT - 16q24.3 [CytoView hg38]
Mapping of homologs : NCBIAPRT [Mapview hg19]  APRT [Mapview hg38]
OMIM102600   614723   
Gene and transcription
Genbank (Entrez)BC106894 BC106895 BC107151 BM423481 BM550173
RefSeq transcript (Entrez)NM_000485 NM_001030018
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_008013 NT_010498 NW_004929403
Consensus coding sequences : CCDS (NCBI)APRT
Cluster EST : UnigeneHs.28914 [ NCBI ]
CGAP (NCI)Hs.28914
Alternative Splicing GalleryENSG00000198931
Gene ExpressionAPRT [ NCBI-GEO ]   APRT [ EBI - ARRAY_EXPRESS ]   APRT [ SEEK ]   APRT [ MEM ]
Gene Expression Viewer (FireBrowse)APRT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)353
GTEX Portal (Tissue expression)APRT
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07741 (Uniprot)
NextProtP07741  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07741
Splice isoforms : SwissVarP07741 (Swissvar)
PhosPhoSitePlusP07741
Domaine pattern : Prosite (Expaxy)PUR_PYR_PR_TRANSFER (PS00103)   
Domains : Interpro (EBI)Ade_phspho_trans    PRibTrfase_dom    PRTase-like   
Domain families : Pfam (Sanger)Pribosyltran (PF00156)   
Domain families : Pfam (NCBI)pfam00156   
DMDM Disease mutations353
Blocks (Seattle)APRT
PDB (SRS)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
PDB (PDBSum)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
PDB (IMB)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
PDB (RSDB)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
Structural Biology KnowledgeBase1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
SCOP (Structural Classification of Proteins)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
CATH (Classification of proteins structures)1OPU    1ORE    1ZN7    1ZN8    1ZN9    4X44    4X45   
SuperfamilyP07741
Human Protein AtlasENSG00000198931
Peptide AtlasP07741
HPRD00029
IPIIPI00218693   IPI00816267   IPI00642457   
Protein Interaction databases
DIP (DOE-UCLA)P07741
IntAct (EBI)P07741
FunCoupENSG00000198931
BioGRIDAPRT
STRING (EMBL)APRT
ZODIACAPRT
Ontologies - Pathways
QuickGOP07741
Ontology : AmiGOadenine binding  adenine phosphoribosyltransferase activity  nucleoplasm  cytoplasm  cytoplasm  cytosol  adenine salvage  lactation  grooming behavior  AMP binding  cellular response to insulin stimulus  purine-containing compound salvage  AMP salvage  extracellular exosome  
Ontology : EGO-EBIadenine binding  adenine phosphoribosyltransferase activity  nucleoplasm  cytoplasm  cytoplasm  cytosol  adenine salvage  lactation  grooming behavior  AMP binding  cellular response to insulin stimulus  purine-containing compound salvage  AMP salvage  extracellular exosome  
Pathways : KEGGPurine metabolism   
NDEx Network
Atlas of Cancer Signalling NetworkAPRT
Wikipedia pathwaysAPRT
Orthology - Evolution
OrthoDB353
GeneTree (enSembl)ENSG00000198931
Phylogenetic Trees/Animal Genes : TreeFamAPRT
Homologs : HomoloGeneAPRT
Homology/Alignments : Family Browser (UCSC)APRT
Gene fusions - Rearrangements
Fusion: TCGAFAM38A APRT 16q24.3 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerAPRT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APRT
dbVarAPRT
ClinVarAPRT
1000_GenomesAPRT 
Exome Variant ServerAPRT
ExAC (Exome Aggregation Consortium)APRT (select the gene name)
Genetic variants : HAPMAP353
Genomic Variants (DGV)APRT [DGVbeta]
Mutations
ICGC Data PortalAPRT 
TCGA Data PortalAPRT 
Broad Tumor PortalAPRT
OASIS PortalAPRT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPRT 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APRT
DgiDB (Drug Gene Interaction Database)APRT
DoCM (Curated mutations)APRT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APRT (select a term)
intoGenAPRT
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:88875877-88878342  ENSG00000198931
CONAN: Copy Number AnalysisAPRT 
Mutations and Diseases : HGMDAPRT
OMIM102600    614723   
MedgenAPRT
Genetic Testing Registry APRT
NextProtP07741 [Medical]
TSGene353
GENETestsAPRT
Huge Navigator APRT [HugePedia]
snp3D : Map Gene to Disease353
BioCentury BCIQAPRT
ClinGenAPRT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD353
Chemical/Pharm GKB GenePA24914
Clinical trialAPRT
Miscellaneous
canSAR (ICR)APRT (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPRT
EVEXAPRT
GoPubMedAPRT
iHOPAPRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 18:58:58 CEST 2016

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