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APRT (adenine phosphoribosyltransferase)

Identity

Other namesAMP
APRTD
HGNC (Hugo) APRT
LocusID (NCBI) 353
Location 16q24.3
Location_base_pair Starts at 88875877 and ends at 88878342 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)APRT   626
Cards
Entrez_Gene (NCBI)APRT  353  adenine phosphoribosyltransferase
GeneCards (Weizmann)APRT
Ensembl hg19 (Hinxton)ENSG00000198931 [Gene_View]  chr16:88875877-88878342 [Contig_View]  APRT [Vega]
Ensembl hg38 (Hinxton)ENSG00000198931 [Gene_View]  chr16:88875877-88878342 [Contig_View]  APRT [Vega]
ICGC DataPortalENSG00000198931
cBioPortalAPRT
AceView (NCBI)APRT
Genatlas (Paris)APRT
WikiGenes353
SOURCE (Princeton)APRT
Genomic and cartography
GoldenPath hg19 (UCSC)APRT  -     chr16:88875877-88878342 -  16q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APRT  -     16q24.3   [Description]    (hg38-Dec_2013)
EnsemblAPRT - 16q24.3 [CytoView hg19]  APRT - 16q24.3 [CytoView hg38]
Mapping of homologs : NCBIAPRT [Mapview hg19]  APRT [Mapview hg38]
OMIM102600   614723   
Gene and transcription
Genbank (Entrez)BC106894 BC106895 BC107151 BM423481 BM550173
RefSeq transcript (Entrez)NM_000485 NM_001030018
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NG_008013 NT_010498 NW_001838334 NW_004929403
Consensus coding sequences : CCDS (NCBI)APRT
Cluster EST : UnigeneHs.28914 [ NCBI ]
CGAP (NCI)Hs.28914
Alternative Splicing : Fast-db (Paris)GSHG0012072
Alternative Splicing GalleryENSG00000198931
Gene ExpressionAPRT [ NCBI-GEO ]     APRT [ SEEK ]   APRT [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07741 (Uniprot)
NextProtP07741  [Medical]
With graphics : InterProP07741
Splice isoforms : SwissVarP07741 (Swissvar)
Domaine pattern : Prosite (Expaxy)PUR_PYR_PR_TRANSFER (PS00103)   
Domains : Interpro (EBI)Ade_phspho_trans    PRibTrfase_dom    PRTase-like   
Related proteins : CluSTrP07741
Domain families : Pfam (Sanger)Pribosyltran (PF00156)   
Domain families : Pfam (NCBI)pfam00156   
DMDM Disease mutations353
Blocks (Seattle)P07741
PDB (SRS)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (PDBSum)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (IMB)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (RSDB)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
Human Protein AtlasENSG00000198931
Peptide AtlasP07741
HPRD00029
IPIIPI00218693   IPI00816267   IPI00642457   
Protein Interaction databases
DIP (DOE-UCLA)P07741
IntAct (EBI)P07741
FunCoupENSG00000198931
BioGRIDAPRT
IntegromeDBAPRT
STRING (EMBL)APRT
Ontologies - Pathways
QuickGOP07741
Ontology : AmiGOadenine binding  adenine phosphoribosyltransferase activity  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  purine nucleobase metabolic process  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  cellular response to insulin stimulus  purine-containing compound salvage  AMP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  extracellular vesicular exosome  
Ontology : EGO-EBIadenine binding  adenine phosphoribosyltransferase activity  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  purine nucleobase metabolic process  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  cellular response to insulin stimulus  purine-containing compound salvage  AMP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  extracellular vesicular exosome  
Pathways : KEGGPurine metabolism   
Protein Interaction DatabaseAPRT
DoCM (Curated mutations)APRT
Wikipedia pathwaysAPRT
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerAPRT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APRT
dbVarAPRT
ClinVarAPRT
1000_GenomesAPRT 
Exome Variant ServerAPRT
SNP (GeneSNP Utah)APRT
SNP : HGBaseAPRT
Genetic variants : HAPMAPAPRT
Genomic VariantsAPRT  APRT [DGVbeta]
Mutations
ICGC Data PortalENSG00000198931 
Somatic Mutations in Cancer : COSMICAPRT 
CONAN: Copy Number AnalysisAPRT 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:88875877-88878342
Mutations and Diseases : HGMDAPRT
OMIM102600    614723   
MedgenAPRT
NextProtP07741 [Medical]
GENETestsAPRT
Disease Genetic AssociationAPRT
Huge Navigator APRT [HugePedia]  APRT [HugeCancerGEM]
snp3D : Map Gene to Disease353
DGIdb (Drug Gene Interaction db)APRT
General knowledge
Homologs : HomoloGeneAPRT
Homology/Alignments : Family Browser (UCSC)APRT
Phylogenetic Trees/Animal Genes : TreeFamAPRT
Chemical/Protein Interactions : CTD353
Chemical/Pharm GKB GenePA24914
Clinical trialAPRT
Cancer Resource (Charite)ENSG00000198931
Other databases
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
CoreMineAPRT
GoPubMedAPRT
iHOPAPRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 20:11:19 CET 2014

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