AQP3 (aquaporin 3 (Gill blood group))

2007-02-01  

Identity

HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
AQP-3,GIL
FUSION GENES

Other Information

Locus ID:

NCBI: 360
MIM: 600170
HGNC: 636
Ensembl: ENSG00000165272

Variants:

dbSNP: 360
ClinVar: 360
TCGA: ENSG00000165272
COSMIC: AQP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165272ENST00000297991Q92482
ENSG00000165272ENST00000473153A0A2R8YDV4
ENSG00000165272ENST00000643650A0A2R8YD22
ENSG00000165272ENST00000645858A0A2R8Y2R4

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Passive transport by AquaporinsREACTOMER-HSA-432047
Vasopressin regulates renal water homeostasis via AquaporinsREACTOMER-HSA-432040

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
179685242008Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing.68
294159902018circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma.63
157039942005Distribution of AQP2 and AQP3 water channels in human tissue microarrays.41
261006682015Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis.41
119187162002Functional expression of AQP3 in human skin epidermis and reconstructed epidermis.35
169185182006Increased expression of aquaporin 3 in atopic eczema.34
238009442014miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer.32
211358722011Aquaporin3 is a sperm water channel essential for postcopulatory sperm osmoadaptation and migration.31
248870092014Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer.31

Citation

Dessen P

AQP3 (aquaporin 3 (Gill blood group))

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43738/aqp3