AQP9 (aquaporin 9)

2007-02-01  

Identity

HGNC
AQP9
LOCATION
15q21.3
LOCUSID
366
ALIAS
AQP-9,HsT17287,SSC1,T17287

Other Information

Locus ID:

NCBI: 366
MIM: 602914
HGNC: 643
Ensembl: ENSG00000103569

Variants:

dbSNP: 366
ClinVar: 366
TCGA: ENSG00000103569
COSMIC: AQP9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103569ENST00000219919O43315
ENSG00000103569ENST00000536493O43315
ENSG00000103569ENST00000558772H0YK62

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Bile secretionKEGGko04976
Bile secretionKEGGhsa04976
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Passive transport by AquaporinsREACTOMER-HSA-432047
Transport of glycerol from adipocytes to the liver by AquaporinsREACTOMER-HSA-432030

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
229160372012Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.70
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
238669712013Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.37
268370492016Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells.29
244630992014Metabolic impact of the glycerol channels AQP7 and AQP9 in adipose tissue and liver.25
153365392004Drug uptake and pharmacological modulation of drug sensitivity in leukemia by AQP9.20
184016712008Influence of morbid obesity and insulin resistance on gene expression levels of AQP7 in visceral adipose tissue and AQP9 in liver.18
173467012007Filopodia are induced by aquaporin-9 expression.17
219454912011Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes.17
218734542011Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization.16

Citation

Dessen P

AQP9 (aquaporin 9)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43685/aqp9