Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARC (activity regulated cytoskeleton associated protein)

Identity

Alias_symbol (synonym)KIAA0278
Arg3.1
Other alias
HGNC (Hugo) ARC
LocusID (NCBI) 23237
Atlas_Id 49990
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 142611044 and ends at 142614472 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARC   648
Cards
Entrez_Gene (NCBI)ARC  23237  activity regulated cytoskeleton associated protein
AliasesArg3.1
GeneCards (Weizmann)ARC
Ensembl hg19 (Hinxton)ENSG00000198576 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198576 [Gene_View]  chr8:142611044-142614472 [Contig_View]  ARC [Vega]
ICGC DataPortalENSG00000198576
TCGA cBioPortalARC
AceView (NCBI)ARC
Genatlas (Paris)ARC
WikiGenes23237
SOURCE (Princeton)ARC
Genetics Home Reference (NIH)ARC
Genomic and cartography
GoldenPath hg38 (UCSC)ARC  -     chr8:142611044-142614472 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARC  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblARC - 8q24.3 [CytoView hg19]  ARC - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIARC [Mapview hg19]  ARC [Mapview hg38]
OMIM612461   
Gene and transcription
Genbank (Entrez)AF193421 AI096899 BC012321 BC075802 BI752734
RefSeq transcript (Entrez)NM_015193
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARC
Cluster EST : UnigeneHs.743662 [ NCBI ]
CGAP (NCI)Hs.743662
Alternative Splicing GalleryENSG00000198576
Gene ExpressionARC [ NCBI-GEO ]   ARC [ EBI - ARRAY_EXPRESS ]   ARC [ SEEK ]   ARC [ MEM ]
Gene Expression Viewer (FireBrowse)ARC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23237
GTEX Portal (Tissue expression)ARC
Human Protein AtlasENSG00000198576-ARC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7LC44   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7LC44  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7LC44
Splice isoforms : SwissVarQ7LC44
PhosPhoSitePlusQ7LC44
Domains : Interpro (EBI)Activity-reg_cytoskelet-assoc   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ARC
DMDM Disease mutations23237
Blocks (Seattle)ARC
SuperfamilyQ7LC44
Human Protein Atlas [tissue]ENSG00000198576-ARC [tissue]
Peptide AtlasQ7LC44
HPRD12469
IPIIPI00000357   
Protein Interaction databases
DIP (DOE-UCLA)Q7LC44
IntAct (EBI)Q7LC44
FunCoupENSG00000198576
BioGRIDARC
STRING (EMBL)ARC
ZODIACARC
Ontologies - Pathways
QuickGOQ7LC44
Ontology : AmiGOacrosomal vesicle  cytoplasm  endosome  plasma membrane  endocytosis  cytoskeleton organization  endoderm development  learning  anterior/posterior pattern specification  postsynaptic density  actin cytoskeleton  cell migration  regulation of cell morphogenesis  cell junction  dendritic spine  postsynaptic membrane  regulation of neuronal synaptic plasticity  regulation of long-term synaptic potentiation  positive regulation of AMPA receptor activity  
Ontology : EGO-EBIacrosomal vesicle  cytoplasm  endosome  plasma membrane  endocytosis  cytoskeleton organization  endoderm development  learning  anterior/posterior pattern specification  postsynaptic density  actin cytoskeleton  cell migration  regulation of cell morphogenesis  cell junction  dendritic spine  postsynaptic membrane  regulation of neuronal synaptic plasticity  regulation of long-term synaptic potentiation  positive regulation of AMPA receptor activity  
Pathways : KEGGAmphetamine addiction   
NDEx NetworkARC
Atlas of Cancer Signalling NetworkARC
Wikipedia pathwaysARC
Orthology - Evolution
OrthoDB23237
GeneTree (enSembl)ENSG00000198576
Phylogenetic Trees/Animal Genes : TreeFamARC
HOVERGENQ7LC44
HOGENOMQ7LC44
Homologs : HomoloGeneARC
Homology/Alignments : Family Browser (UCSC)ARC
Gene fusions - Rearrangements
Tumor Fusion PortalARC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARC
dbVarARC
ClinVarARC
1000_GenomesARC 
Exome Variant ServerARC
ExAC (Exome Aggregation Consortium)ENSG00000198576
GNOMAD BrowserENSG00000198576
Genetic variants : HAPMAP23237
Genomic Variants (DGV)ARC [DGVbeta]
DECIPHERARC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARC 
Mutations
ICGC Data PortalARC 
TCGA Data PortalARC 
Broad Tumor PortalARC
OASIS PortalARC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARC
DgiDB (Drug Gene Interaction Database)ARC
DoCM (Curated mutations)ARC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARC (select a term)
intoGenARC
Cancer3DARC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612461   
Orphanet
DisGeNETARC
MedgenARC
Genetic Testing Registry ARC
NextProtQ7LC44 [Medical]
TSGene23237
GENETestsARC
Target ValidationARC
Huge Navigator ARC [HugePedia]
snp3D : Map Gene to Disease23237
BioCentury BCIQARC
ClinGenARC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23237
Chemical/Pharm GKB GenePA24930
Clinical trialARC
Miscellaneous
canSAR (ICR)ARC (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARC
EVEXARC
GoPubMedARC
iHOPARC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:29 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.