Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARF3 (ADP ribosylation factor 3)

Identity

Other alias-
HGNC (Hugo) ARF3
LocusID (NCBI) 377
Atlas_Id 43124
Location 12q13.12  [Link to chromosome band 12q13]
Location_base_pair Starts at 48936209 and ends at 48957469 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARF3 (12q13.12) / ARF3 (12q13.12)ARF3 (12q13.12) / CHFR (12q24.33)ARF3 (12q13.12) / ITPR2 (12p12.1)
ARF3 (12q13.12) / NDUFA6 (22q13.2)ARF3 (12q13.12) / OGFOD2 (12q24.31)ARF3 (12q13.12) / SLC38A7 (16q21)
ARF3 (12q13.12) / TAB2 (6q25.1)CCNB1IP1 (14q11.2) / ARF3 (12q13.12)DDX23 (12q13.12) / ARF3 (12q13.12)
GBF1 (10q24.32) / ARF3 (12q13.12)RAD23A (19p13.2) / ARF3 (12q13.12)ARF3 12q13.12 / CHFR 12q24.33
DDX23 12q13.12 / ARF3 12q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;11)(q13;q23) KMT2A/SMAP1


External links

Nomenclature
HGNC (Hugo)ARF3   654
Cards
Entrez_Gene (NCBI)ARF3  377  ADP ribosylation factor 3
Aliases
GeneCards (Weizmann)ARF3
Ensembl hg19 (Hinxton)ENSG00000134287 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134287 [Gene_View]  chr12:48936209-48957469 [Contig_View]  ARF3 [Vega]
ICGC DataPortalENSG00000134287
TCGA cBioPortalARF3
AceView (NCBI)ARF3
Genatlas (Paris)ARF3
WikiGenes377
SOURCE (Princeton)ARF3
Genetics Home Reference (NIH)ARF3
Genomic and cartography
GoldenPath hg38 (UCSC)ARF3  -     chr12:48936209-48957469 -  12q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARF3  -     12q13.12   [Description]    (hg19-Feb_2009)
EnsemblARF3 - 12q13.12 [CytoView hg19]  ARF3 - 12q13.12 [CytoView hg38]
Mapping of homologs : NCBIARF3 [Mapview hg19]  ARF3 [Mapview hg38]
OMIM103190   
Gene and transcription
Genbank (Entrez)AF493882 AK291633 AK300080 AK303726 AK315970
RefSeq transcript (Entrez)NM_001659
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARF3
Cluster EST : UnigeneHs.119177 [ NCBI ]
CGAP (NCI)Hs.119177
Alternative Splicing GalleryENSG00000134287
Gene ExpressionARF3 [ NCBI-GEO ]   ARF3 [ EBI - ARRAY_EXPRESS ]   ARF3 [ SEEK ]   ARF3 [ MEM ]
Gene Expression Viewer (FireBrowse)ARF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)377
GTEX Portal (Tissue expression)ARF3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61204   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61204  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61204
Splice isoforms : SwissVarP61204
PhosPhoSitePlusP61204
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)ARF3
DMDM Disease mutations377
Blocks (Seattle)ARF3
SuperfamilyP61204
Human Protein AtlasENSG00000134287
Peptide AtlasP61204
HPRD00056
IPIIPI00215917   IPI00910783   IPI01015420   IPI00797941   IPI01011566   IPI01012104   
Protein Interaction databases
DIP (DOE-UCLA)P61204
IntAct (EBI)P61204
FunCoupENSG00000134287
BioGRIDARF3
STRING (EMBL)ARF3
ZODIACARF3
Ontologies - Pathways
QuickGOP61204
Ontology : AmiGOGolgi membrane  GTPase activity  GTP binding  phosphatidylinositol biosynthetic process  retrograde vesicle-mediated transport, Golgi to ER  small GTPase mediated signal transduction  protein transport  perinuclear region of cytoplasm  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  GTPase activity  GTP binding  phosphatidylinositol biosynthetic process  retrograde vesicle-mediated transport, Golgi to ER  small GTPase mediated signal transduction  protein transport  perinuclear region of cytoplasm  extracellular exosome  
NDEx NetworkARF3
Atlas of Cancer Signalling NetworkARF3
Wikipedia pathwaysARF3
Orthology - Evolution
OrthoDB377
GeneTree (enSembl)ENSG00000134287
Phylogenetic Trees/Animal Genes : TreeFamARF3
HOVERGENP61204
HOGENOMP61204
Homologs : HomoloGeneARF3
Homology/Alignments : Family Browser (UCSC)ARF3
Gene fusions - Rearrangements
Fusion : MitelmanARF3/CHFR [12q13.12/12q24.33]  
Fusion : MitelmanARF3/TAB2 [12q13.12/6q25.1]  [t(6;12)(q25;q13)]  
Fusion : MitelmanDDX23/ARF3 [12q13.12/12q13.12]  [t(12;12)(q13;q13)]  
Fusion: TCGAARF3 12q13.12 CHFR 12q24.33 LUAD
Fusion: TCGADDX23 12q13.12 ARF3 12q13.12 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARF3
dbVarARF3
ClinVarARF3
1000_GenomesARF3 
Exome Variant ServerARF3
ExAC (Exome Aggregation Consortium)ARF3 (select the gene name)
Genetic variants : HAPMAP377
Genomic Variants (DGV)ARF3 [DGVbeta]
DECIPHERARF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARF3 
Mutations
ICGC Data PortalARF3 
TCGA Data PortalARF3 
Broad Tumor PortalARF3
OASIS PortalARF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARF3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARF3
DgiDB (Drug Gene Interaction Database)ARF3
DoCM (Curated mutations)ARF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARF3 (select a term)
intoGenARF3
Cancer3DARF3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103190   
Orphanet
MedgenARF3
Genetic Testing Registry ARF3
NextProtP61204 [Medical]
TSGene377
GENETestsARF3
Target ValidationARF3
Huge Navigator ARF3 [HugePedia]
snp3D : Map Gene to Disease377
BioCentury BCIQARF3
ClinGenARF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD377
Chemical/Pharm GKB GenePA24936
Clinical trialARF3
Miscellaneous
canSAR (ICR)ARF3 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARF3
EVEXARF3
GoPubMedARF3
iHOPARF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:24:11 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.