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ARF5 (ADP ribosylation factor 5)

Identity

Other alias-
HGNC (Hugo) ARF5
LocusID (NCBI) 381
Atlas_Id 43126
Location 7q32.1  [Link to chromosome band 7q32]
Location_base_pair Starts at 127588352 and ends at 127591705 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARF5 (7q32.1) / ARF5 (7q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;11)(q13;q23) KMT2A/SMAP1


External links

Nomenclature
HGNC (Hugo)ARF5   658
Cards
Entrez_Gene (NCBI)ARF5  381  ADP ribosylation factor 5
Aliases
GeneCards (Weizmann)ARF5
Ensembl hg19 (Hinxton)ENSG00000004059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000004059 [Gene_View]  chr7:127588352-127591705 [Contig_View]  ARF5 [Vega]
ICGC DataPortalENSG00000004059
TCGA cBioPortalARF5
AceView (NCBI)ARF5
Genatlas (Paris)ARF5
WikiGenes381
SOURCE (Princeton)ARF5
Genetics Home Reference (NIH)ARF5
Genomic and cartography
GoldenPath hg38 (UCSC)ARF5  -     chr7:127588352-127591705 +  7q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARF5  -     7q32.1   [Description]    (hg19-Feb_2009)
EnsemblARF5 - 7q32.1 [CytoView hg19]  ARF5 - 7q32.1 [CytoView hg38]
Mapping of homologs : NCBIARF5 [Mapview hg19]  ARF5 [Mapview hg38]
OMIM103188   
Gene and transcription
Genbank (Entrez)AF493884 AK297026 AK307297 AK308548 AK312107
RefSeq transcript (Entrez)NM_001662
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARF5
Cluster EST : UnigeneHs.653202 [ NCBI ]
CGAP (NCI)Hs.653202
Alternative Splicing GalleryENSG00000004059
Gene ExpressionARF5 [ NCBI-GEO ]   ARF5 [ EBI - ARRAY_EXPRESS ]   ARF5 [ SEEK ]   ARF5 [ MEM ]
Gene Expression Viewer (FireBrowse)ARF5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)381
GTEX Portal (Tissue expression)ARF5
Human Protein AtlasENSG00000004059-ARF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP84085   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP84085  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP84085
Splice isoforms : SwissVarP84085
PhosPhoSitePlusP84085
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)ARF5
DMDM Disease mutations381
Blocks (Seattle)ARF5
PDB (SRS)2B6H   
PDB (PDBSum)2B6H   
PDB (IMB)2B6H   
PDB (RSDB)2B6H   
Structural Biology KnowledgeBase2B6H   
SCOP (Structural Classification of Proteins)2B6H   
CATH (Classification of proteins structures)2B6H   
SuperfamilyP84085
Human Protein Atlas [tissue]ENSG00000004059-ARF5 [tissue]
Peptide AtlasP84085
HPRD00055
IPIIPI00215919   IPI00853337   
Protein Interaction databases
DIP (DOE-UCLA)P84085
IntAct (EBI)P84085
FunCoupENSG00000004059
BioGRIDARF5
STRING (EMBL)ARF5
ZODIACARF5
Ontologies - Pathways
QuickGOP84085
Ontology : AmiGOGTPase activity  protein binding  GTP binding  Golgi apparatus  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  small GTPase mediated signal transduction  protein transport  perinuclear region of cytoplasm  extracellular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  Golgi apparatus  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  small GTPase mediated signal transduction  protein transport  perinuclear region of cytoplasm  extracellular exosome  
NDEx NetworkARF5
Atlas of Cancer Signalling NetworkARF5
Wikipedia pathwaysARF5
Orthology - Evolution
OrthoDB381
GeneTree (enSembl)ENSG00000004059
Phylogenetic Trees/Animal Genes : TreeFamARF5
HOVERGENP84085
HOGENOMP84085
Homologs : HomoloGeneARF5
Homology/Alignments : Family Browser (UCSC)ARF5
Gene fusions - Rearrangements
Tumor Fusion PortalARF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARF5
dbVarARF5
ClinVarARF5
1000_GenomesARF5 
Exome Variant ServerARF5
ExAC (Exome Aggregation Consortium)ENSG00000004059
GNOMAD BrowserENSG00000004059
Genetic variants : HAPMAP381
Genomic Variants (DGV)ARF5 [DGVbeta]
DECIPHERARF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARF5 
Mutations
ICGC Data PortalARF5 
TCGA Data PortalARF5 
Broad Tumor PortalARF5
OASIS PortalARF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARF5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARF5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARF5
DgiDB (Drug Gene Interaction Database)ARF5
DoCM (Curated mutations)ARF5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARF5 (select a term)
intoGenARF5
Cancer3DARF5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103188   
Orphanet
DisGeNETARF5
MedgenARF5
Genetic Testing Registry ARF5
NextProtP84085 [Medical]
TSGene381
GENETestsARF5
Target ValidationARF5
Huge Navigator ARF5 [HugePedia]
snp3D : Map Gene to Disease381
BioCentury BCIQARF5
ClinGenARF5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD381
Chemical/Pharm GKB GenePA24941
Clinical trialARF5
Miscellaneous
canSAR (ICR)ARF5 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARF5
EVEXARF5
GoPubMedARF5
iHOPARF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:30 CET 2017

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