Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARF5 (ADP ribosylation factor 5)

Identity

Alias (NCBI)-
HGNC (Hugo) ARF5
LocusID (NCBI) 381
Atlas_Id 43126
Location 7q32.1  [Link to chromosome band 7q32]
Location_base_pair Starts at 127588411 and ends at 127591700 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARF5 (7q32.1)::ARF5 (7q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;11)(q13;q23) KMT2A::SMAP1


External links

 

Nomenclature
HGNC (Hugo)ARF5   658
Cards
Entrez_Gene (NCBI)ARF5    ADP ribosylation factor 5
Aliases
GeneCards (Weizmann)ARF5
Ensembl hg19 (Hinxton)ENSG00000004059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000004059 [Gene_View]  ENSG00000004059 [Sequence]  chr7:127588411-127591700 [Contig_View]  ARF5 [Vega]
ICGC DataPortalENSG00000004059
TCGA cBioPortalARF5
AceView (NCBI)ARF5
Genatlas (Paris)ARF5
SOURCE (Princeton)ARF5
Genetics Home Reference (NIH)ARF5
Genomic and cartography
GoldenPath hg38 (UCSC)ARF5  -     chr7:127588411-127591700 +  7q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARF5  -     7q32.1   [Description]    (hg19-Feb_2009)
GoldenPathARF5 - 7q32.1 [CytoView hg19]  ARF5 - 7q32.1 [CytoView hg38]
ImmunoBaseENSG00000004059
Genome Data Viewer NCBIARF5 [Mapview hg19]  
OMIM103188   
Gene and transcription
Genbank (Entrez)AF493884 AK297026 AK307297 AK308548 AK312107
RefSeq transcript (Entrez)NM_001662
Consensus coding sequences : CCDS (NCBI)ARF5
Gene ExpressionARF5 [ NCBI-GEO ]   ARF5 [ EBI - ARRAY_EXPRESS ]   ARF5 [ SEEK ]   ARF5 [ MEM ]
Gene Expression Viewer (FireBrowse)ARF5 [ Firebrowse - Broad ]
GenevisibleExpression of ARF5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)381
GTEX Portal (Tissue expression)ARF5
Human Protein AtlasENSG00000004059-ARF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP84085   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP84085  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP84085
PhosPhoSitePlusP84085
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)ARF5
PDB (RSDB)2B6H   
PDB Europe2B6H   
PDB (PDBSum)2B6H   
PDB (IMB)2B6H   
Structural Biology KnowledgeBase2B6H   
SCOP (Structural Classification of Proteins)2B6H   
CATH (Classification of proteins structures)2B6H   
SuperfamilyP84085
AlphaFold pdb e-kbP84085   
Human Protein Atlas [tissue]ENSG00000004059-ARF5 [tissue]
HPRD00055
Protein Interaction databases
DIP (DOE-UCLA)P84085
IntAct (EBI)P84085
BioGRIDARF5
STRING (EMBL)ARF5
ZODIACARF5
Ontologies - Pathways
QuickGOP84085
Ontology : AmiGOGTPase activity  protein binding  GTP binding  cytoplasm  Golgi apparatus  plasma membrane  intracellular protein transport  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  vesicle-mediated transport  perinuclear region of cytoplasm  extracellular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  cytoplasm  Golgi apparatus  plasma membrane  intracellular protein transport  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  vesicle-mediated transport  perinuclear region of cytoplasm  extracellular exosome  
NDEx NetworkARF5
Atlas of Cancer Signalling NetworkARF5
Wikipedia pathwaysARF5
Orthology - Evolution
OrthoDB381
GeneTree (enSembl)ENSG00000004059
Phylogenetic Trees/Animal Genes : TreeFamARF5
Homologs : HomoloGeneARF5
Homology/Alignments : Family Browser (UCSC)ARF5
Gene fusions - Rearrangements
Fusion : QuiverARF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARF5
dbVarARF5
ClinVarARF5
MonarchARF5
1000_GenomesARF5 
Exome Variant ServerARF5
GNOMAD BrowserENSG00000004059
Varsome BrowserARF5
ACMGARF5 variants
VarityP84085
Genomic Variants (DGV)ARF5 [DGVbeta]
DECIPHERARF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARF5 
Mutations
ICGC Data PortalARF5 
TCGA Data PortalARF5 
Broad Tumor PortalARF5
OASIS PortalARF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARF5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DARF5
Mutations and Diseases : HGMDARF5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaARF5
DgiDB (Drug Gene Interaction Database)ARF5
DoCM (Curated mutations)ARF5
CIViC (Clinical Interpretations of Variants in Cancer)ARF5
Cancer3DARF5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103188   
Orphanet
DisGeNETARF5
MedgenARF5
Genetic Testing Registry ARF5
NextProtP84085 [Medical]
GENETestsARF5
Target ValidationARF5
Huge Navigator ARF5 [HugePedia]
ClinGenARF5
Clinical trials, drugs, therapy
MyCancerGenomeARF5
Protein Interactions : CTDARF5
Pharm GKB GenePA24941
PharosP84085
Clinical trialARF5
Miscellaneous
canSAR (ICR)ARF5
HarmonizomeARF5
ARCHS4ARF5
DataMed IndexARF5
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXARF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 12:22:59 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.