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ARFGAP3 (ADP ribosylation factor GTPase activating protein 3)

Identity

Alias_namesARFGAP1
ADP-ribosylation factor GTPase activating protein 1
Other alias
HGNC (Hugo) ARFGAP3
LocusID (NCBI) 26286
Atlas_Id 52719
Location 22q13.2  [Link to chromosome band 22q13]
Location_base_pair Starts at 42796526 and ends at 42857402 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARFGAP3 (22q13.2) / ARFGAP3 (22q13.2)PACSIN2 (22q13.2) / ARFGAP3 (22q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARFGAP3   661
Cards
Entrez_Gene (NCBI)ARFGAP3  26286  ADP ribosylation factor GTPase activating protein 3
AliasesARFGAP1
GeneCards (Weizmann)ARFGAP3
Ensembl hg19 (Hinxton)ENSG00000242247 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000242247 [Gene_View]  chr22:42796526-42857402 [Contig_View]  ARFGAP3 [Vega]
ICGC DataPortalENSG00000242247
TCGA cBioPortalARFGAP3
AceView (NCBI)ARFGAP3
Genatlas (Paris)ARFGAP3
WikiGenes26286
SOURCE (Princeton)ARFGAP3
Genetics Home Reference (NIH)ARFGAP3
Genomic and cartography
GoldenPath hg38 (UCSC)ARFGAP3  -     chr22:42796526-42857402 -  22q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARFGAP3  -     22q13.2   [Description]    (hg19-Feb_2009)
EnsemblARFGAP3 - 22q13.2 [CytoView hg19]  ARFGAP3 - 22q13.2 [CytoView hg38]
Mapping of homologs : NCBIARFGAP3 [Mapview hg19]  ARFGAP3 [Mapview hg38]
OMIM612439   
Gene and transcription
Genbank (Entrez)AF111847 AK002083 AK022768 AK127525 AK297635
RefSeq transcript (Entrez)NM_001142293 NM_014570
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARFGAP3
Cluster EST : UnigeneHs.685225 [ NCBI ]
CGAP (NCI)Hs.685225
Alternative Splicing GalleryENSG00000242247
Gene ExpressionARFGAP3 [ NCBI-GEO ]   ARFGAP3 [ EBI - ARRAY_EXPRESS ]   ARFGAP3 [ SEEK ]   ARFGAP3 [ MEM ]
Gene Expression Viewer (FireBrowse)ARFGAP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26286
GTEX Portal (Tissue expression)ARFGAP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP61   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP61  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP61
Splice isoforms : SwissVarQ9NP61
PhosPhoSitePlusQ9NP61
Domaine pattern : Prosite (Expaxy)ARFGAP (PS50115)   
Domains : Interpro (EBI)ArfGAP   
Domain families : Pfam (Sanger)ArfGap (PF01412)   
Domain families : Pfam (NCBI)pfam01412   
Domain families : Smart (EMBL)ArfGap (SM00105)  
Conserved Domain (NCBI)ARFGAP3
DMDM Disease mutations26286
Blocks (Seattle)ARFGAP3
PDB (SRS)2CRW   
PDB (PDBSum)2CRW   
PDB (IMB)2CRW   
PDB (RSDB)2CRW   
Structural Biology KnowledgeBase2CRW   
SCOP (Structural Classification of Proteins)2CRW   
CATH (Classification of proteins structures)2CRW   
SuperfamilyQ9NP61
Human Protein AtlasENSG00000242247
Peptide AtlasQ9NP61
HPRD06444
IPIIPI00299263   IPI00922812   IPI00877805   IPI00879282   IPI01019115   IPI00917741   IPI00915304   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP61
IntAct (EBI)Q9NP61
FunCoupENSG00000242247
BioGRIDARFGAP3
STRING (EMBL)ARFGAP3
ZODIACARFGAP3
Ontologies - Pathways
QuickGOQ9NP61
Ontology : AmiGOGolgi membrane  GTPase activator activity  protein binding  Golgi apparatus  cytosol  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  protein transporter activity  protein secretion  membrane  vesicle-mediated transport  positive regulation of GTPase activity  metal ion binding  
Ontology : EGO-EBIGolgi membrane  GTPase activator activity  protein binding  Golgi apparatus  cytosol  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  protein transporter activity  protein secretion  membrane  vesicle-mediated transport  positive regulation of GTPase activity  metal ion binding  
Pathways : BIOCARTAADP-Ribosylation Factor [Genes]   
Pathways : KEGGEndocytosis   
NDEx NetworkARFGAP3
Atlas of Cancer Signalling NetworkARFGAP3
Wikipedia pathwaysARFGAP3
Orthology - Evolution
OrthoDB26286
GeneTree (enSembl)ENSG00000242247
Phylogenetic Trees/Animal Genes : TreeFamARFGAP3
HOVERGENQ9NP61
HOGENOMQ9NP61
Homologs : HomoloGeneARFGAP3
Homology/Alignments : Family Browser (UCSC)ARFGAP3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARFGAP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARFGAP3
dbVarARFGAP3
ClinVarARFGAP3
1000_GenomesARFGAP3 
Exome Variant ServerARFGAP3
ExAC (Exome Aggregation Consortium)ARFGAP3 (select the gene name)
Genetic variants : HAPMAP26286
Genomic Variants (DGV)ARFGAP3 [DGVbeta]
DECIPHERARFGAP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARFGAP3 
Mutations
ICGC Data PortalARFGAP3 
TCGA Data PortalARFGAP3 
Broad Tumor PortalARFGAP3
OASIS PortalARFGAP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARFGAP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARFGAP3
intOGen PortalARFGAP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARFGAP3
DgiDB (Drug Gene Interaction Database)ARFGAP3
DoCM (Curated mutations)ARFGAP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARFGAP3 (select a term)
intoGenARFGAP3
Cancer3DARFGAP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612439   
Orphanet
MedgenARFGAP3
Genetic Testing Registry ARFGAP3
NextProtQ9NP61 [Medical]
TSGene26286
GENETestsARFGAP3
Target ValidationARFGAP3
Huge Navigator ARFGAP3 [HugePedia]
snp3D : Map Gene to Disease26286
BioCentury BCIQARFGAP3
ClinGenARFGAP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26286
Chemical/Pharm GKB GenePA35024
Clinical trialARFGAP3
Miscellaneous
canSAR (ICR)ARFGAP3 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARFGAP3
EVEXARFGAP3
GoPubMedARFGAP3
iHOPARFGAP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:57:47 CEST 2017

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