Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARG2 (arginase 2)

Identity

Alias_namesarginase
Other alias-
HGNC (Hugo) ARG2
LocusID (NCBI) 384
Atlas_Id 50128
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 68086579 and ends at 68118436 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EMILIN1 (2p23.3) / ARG2 (14q24.1)IL34 (16q22.1) / ARG2 (14q24.1)IL34 16q22.1 / ARG2 14q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARG2   664
Cards
Entrez_Gene (NCBI)ARG2  384  arginase 2
Aliases
GeneCards (Weizmann)ARG2
Ensembl hg19 (Hinxton)ENSG00000081181 [Gene_View]  chr14:68086579-68118436 [Contig_View]  ARG2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000081181 [Gene_View]  chr14:68086579-68118436 [Contig_View]  ARG2 [Vega]
ICGC DataPortalENSG00000081181
TCGA cBioPortalARG2
AceView (NCBI)ARG2
Genatlas (Paris)ARG2
WikiGenes384
SOURCE (Princeton)ARG2
Genetics Home Reference (NIH)ARG2
Genomic and cartography
GoldenPath hg19 (UCSC)ARG2  -     chr14:68086579-68118436 +  14q24.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARG2  -     14q24.1   [Description]    (hg38-Dec_2013)
EnsemblARG2 - 14q24.1 [CytoView hg19]  ARG2 - 14q24.1 [CytoView hg38]
Mapping of homologs : NCBIARG2 [Mapview hg19]  ARG2 [Mapview hg38]
OMIM107830   
Gene and transcription
Genbank (Entrez)AK312484 AL135439 AY074489 BC001350 BC008464
RefSeq transcript (Entrez)NM_001172
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_011964 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)ARG2
Cluster EST : UnigeneHs.226007 [ NCBI ]
CGAP (NCI)Hs.226007
Alternative Splicing GalleryENSG00000081181
Gene ExpressionARG2 [ NCBI-GEO ]   ARG2 [ EBI - ARRAY_EXPRESS ]   ARG2 [ SEEK ]   ARG2 [ MEM ]
Gene Expression Viewer (FireBrowse)ARG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)384
GTEX Portal (Tissue expression)ARG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78540   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78540  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78540
Splice isoforms : SwissVarP78540
PhosPhoSitePlusP78540
Domaine pattern : Prosite (Expaxy)ARGINASE_1 (PS01053)    ARGINASE_2 (PS51409)   
Domains : Interpro (EBI)Arginase    Ureohydrolase    Ureohydrolase_domain    Ureohydrolase_Mn_BS   
Domain families : Pfam (Sanger)Arginase (PF00491)   
Domain families : Pfam (NCBI)pfam00491   
Conserved Domain (NCBI)ARG2
DMDM Disease mutations384
Blocks (Seattle)ARG2
PDB (SRS)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
PDB (PDBSum)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
PDB (IMB)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
PDB (RSDB)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
Structural Biology KnowledgeBase1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
SCOP (Structural Classification of Proteins)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
CATH (Classification of proteins structures)1PQ3    4HZE    4I06    4IE2    4IE3    4IXU    4IXV   
SuperfamilyP78540
Human Protein AtlasENSG00000081181
Peptide AtlasP78540
HPRD00143
IPIIPI00020332   
Protein Interaction databases
DIP (DOE-UCLA)P78540
IntAct (EBI)P78540
FunCoupENSG00000081181
BioGRIDARG2
STRING (EMBL)ARG2
ZODIACARG2
Ontologies - Pathways
QuickGOP78540
Ontology : AmiGOurea cycle  urea cycle  ureteric bud development  arginase activity  arginase activity  mitochondrion  mitochondrial matrix  arginine metabolic process  nitric oxide biosynthetic process  striated muscle contraction  metal ion binding  
Ontology : EGO-EBIurea cycle  urea cycle  ureteric bud development  arginase activity  arginase activity  mitochondrion  mitochondrial matrix  arginine metabolic process  nitric oxide biosynthetic process  striated muscle contraction  metal ion binding  
Pathways : KEGGArginine and proline metabolism    Amoebiasis   
NDEx NetworkARG2
Atlas of Cancer Signalling NetworkARG2
Wikipedia pathwaysARG2
Orthology - Evolution
OrthoDB384
GeneTree (enSembl)ENSG00000081181
Phylogenetic Trees/Animal Genes : TreeFamARG2
HOVERGENP78540
HOGENOMP78540
Homologs : HomoloGeneARG2
Homology/Alignments : Family Browser (UCSC)ARG2
Gene fusions - Rearrangements
Fusion : MitelmanIL34/ARG2 [16q22.1/14q24.1]  [t(14;16)(q24;q22)]  
Fusion: TCGAIL34 16q22.1 ARG2 14q24.1 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARG2
dbVarARG2
ClinVarARG2
1000_GenomesARG2 
Exome Variant ServerARG2
ExAC (Exome Aggregation Consortium)ARG2 (select the gene name)
Genetic variants : HAPMAP384
Genomic Variants (DGV)ARG2 [DGVbeta]
DECIPHER (Syndromes)14:68086579-68118436  ENSG00000081181
CONAN: Copy Number AnalysisARG2 
Mutations
ICGC Data PortalARG2 
TCGA Data PortalARG2 
Broad Tumor PortalARG2
OASIS PortalARG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
LOVD (Leiden Open Variation Database)The Globin Gene Server
BioMutasearch ARG2
DgiDB (Drug Gene Interaction Database)ARG2
DoCM (Curated mutations)ARG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARG2 (select a term)
intoGenARG2
Cancer3DARG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM107830   
Orphanet
MedgenARG2
Genetic Testing Registry ARG2
NextProtP78540 [Medical]
TSGene384
GENETestsARG2
Huge Navigator ARG2 [HugePedia]
snp3D : Map Gene to Disease384
BioCentury BCIQARG2
ClinGenARG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD384
Chemical/Pharm GKB GenePA24948
Clinical trialARG2
Miscellaneous
canSAR (ICR)ARG2 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARG2
EVEXARG2
GoPubMedARG2
iHOPARG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:56:19 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.