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ARHGAP12 (Rho GTPase activating protein 12)

Identity

Other names-
HGNC (Hugo) ARHGAP12
LocusID (NCBI) 94134
Location 10p11.22
Location_base_pair Starts at 32094326 and ends at 32217804 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ARHGAP12   16348
Entrez_Gene (NCBI)ARHGAP12  94134  Rho GTPase activating protein 12
Cards
GeneCards (Weizmann)ARHGAP12
Ensembl (Hinxton)ENSG00000165322 [Gene_View]  chr10:32094326-32217804 [Contig_View]  ARHGAP12 [Vega]
AceView (NCBI)ARHGAP12
Genatlas (Paris)ARHGAP12
SOURCE (Stanford)NM_001270695 NM_001270696 NM_001270697 NM_001270698 NM_001270699 NM_018287
Genomic and cartography
GoldenPath (UCSC)ARHGAP12  -  10p11.22   chr10:32094326-32217804 -  10p11.22   [Description]    (hg19-Feb_2009)
EnsemblARHGAP12 - 10p11.22 [CytoView]
Mapping of homologs : NCBIARHGAP12 [Mapview]
OMIM610577   
Gene and transcription
Genbank (Entrez)AF131804 AK000744 AK001833 AK025438 AK091182
RefSeq transcript (SRS)NM_001270695 NM_001270696 NM_001270697 NM_001270698 NM_001270699 NM_018287
RefSeq transcript (Entrez)NM_001270695 NM_001270696 NM_001270697 NM_001270698 NM_001270699 NM_018287
RefSeq genomic (SRS)AC_000142 NC_000010 NC_018921 NT_008705 NW_001837932 NW_004078062
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_008705 NW_001837932 NW_004078062
Consensus coding sequences : CCDS (NCBI)ARHGAP12
Cluster EST : UnigeneHs.741991 [ SRS ] Hs.741991 [ NCBI ]
CGAP (NCI)Hs.741991
Alternative Splicing : Fast-db (Paris)GSHG0003980
Alternative Splicing GalleryENSG00000165322
Gene ExpressionARHGAP12 [ NCBI-GEO ]   ARHGAP12 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWW6 (SRS) Q8IWW6 (Uniprot)
NextProtQ8IWW6
With graphics : InterProQ8IWW6
Splice isoforms : SwissVarQ8IWW6(Swissvar)
Domaine pattern : Prosite (SRS)PH_DOMAIN (PS50003)    RHOGAP (PS50238)    SH3 (PS50002)    WW_DOMAIN_1 (PS01159)    WW_DOMAIN_2 (PS50020)   
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    RHOGAP (PS50238)    SH3 (PS50002)    WW_DOMAIN_1 (PS01159)    WW_DOMAIN_2 (PS50020)   
Domains : Interpro (SRS)PH_like_dom    Pleckstrin_homology    Rho_GTPase_activating    Rho_GTPase_activation_prot    RhoGAP_dom    SH3_domain    WW_Rsp5_WWP   
Domains : Interpro (EBI)PH_like_dom    Pleckstrin_homology    Rho_GTPase_activating    Rho_GTPase_activation_prot    RhoGAP_dom    SH3_domain    WW_Rsp5_WWP   
Related proteins : CluSTrQ8IWW6
Domain families : Pfam (SRS)PH (PF00169)    RhoGAP (PF00620)    WW (PF00397)   
Domain families : Pfam (Sanger)PH (PF00169)    RhoGAP (PF00620)    WW (PF00397)   
Domain families : Pfam (NCBI)pfam00169    pfam00620    pfam00397   
Domain families : Smart (EMBL)PH (SM00233)  RhoGAP (SM00324)  SH3 (SM00326)  WW (SM00456)  
DMDM94134
Blocks (Seattle)Q8IWW6
Human Protein AtlasENSG00000165322
HPRD06446
IPIIPI00328279   IPI00217418   IPI00410501   IPI00643949   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWW6
IntAct (EBI)Q8IWW6
FunCoupENSG00000165322
REACTOMEARHGAP12
Protein Interaction Database94134
BioGRIDARHGAP12
InParanoidQ8IWW6
Interologous Interaction database Q8IWW6
IntegromeDBARHGAP12
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ARHGAP12
SNP (GeneSNP Utah)ARHGAP12
SNP : HGBaseARHGAP12
Genetic variants : HAPMAPARHGAP12
Somatic Mutations in Cancer : COSMICARHGAP12 
CONAN: Copy Number AnalysisARHGAP12 
Mutations and Diseases : HGMDARHGAP12
OMIM610577   
GENETests610577   
Disease Genetic AssociationARHGAP12
Huge Navigator ARHGAP12 [HugePedia]  ARHGAP12 [HugeCancerGEM]
Genomic VariantsARHGAP12  ARHGAP12 [DGVbeta]
snp3D : Map Gene to Disease94134
General knowledge
Homologs : HomoloGeneARHGAP12
Homology/Alignments : Family Browser (UCSC)ARHGAP12
Phylogenetic Trees/Animal Genes : TreeFamARHGAP12
Chemical/Protein Interactions : CTD94134
Chemical/Pharm GKB GenePA24957
Clinical trialARHGAP12
Cancer Resource (Charite)ENSG00000165322
Ontology : AmiGOGTPase activator activity  phospholipid binding  cytosol  small GTPase mediated signal transduction  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBIGTPase activator activity  phospholipid binding  cytosol  small GTPase mediated signal transduction  regulation of small GTPase mediated signal transduction  
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
PubGeneARHGAP12
iHOPARHGAP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:46:59 CEST 2013
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