Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ARHGAP22 (Rho GTPase activating protein 22)

Identity

Other namesRhoGAP2
RhoGap22
HGNC (Hugo) ARHGAP22
LocusID (NCBI) 58504
Location 10q11.22
Location_base_pair Starts at 49654068 and ends at 49813176 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ARHGAP22   30320
Cards
Entrez_Gene (NCBI)ARHGAP22  58504  Rho GTPase activating protein 22
GeneCards (Weizmann)ARHGAP22
Ensembl hg19 (Hinxton)ENSG00000128805 [Gene_View]  chr10:49654068-49813176 [Contig_View]  ARHGAP22 [Vega]
Ensembl hg38 (Hinxton)ENSG00000128805 [Gene_View]  chr10:49654068-49813176 [Contig_View]  ARHGAP22 [Vega]
ICGC DataPortalENSG00000128805
cBioPortalARHGAP22
AceView (NCBI)ARHGAP22
Genatlas (Paris)ARHGAP22
WikiGenes58504
SOURCE (Princeton)ARHGAP22
Genomic and cartography
GoldenPath hg19 (UCSC)ARHGAP22  -     chr10:49654068-49813176 -  10q11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARHGAP22  -     10q11.22   [Description]    (hg38-Dec_2013)
EnsemblARHGAP22 - 10q11.22 [CytoView hg19]  ARHGAP22 - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIARHGAP22 [Mapview hg19]  ARHGAP22 [Mapview hg38]
OMIM610585   
Gene and transcription
Genbank (Entrez)AK055037 AK055937 AK127586 AK293579 AY324801
RefSeq transcript (Entrez)NM_001256024 NM_001256025 NM_001256026 NM_001256027 NM_021226
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001837974 NW_004929376
Consensus coding sequences : CCDS (NCBI)ARHGAP22
Cluster EST : UnigeneHs.655672 [ NCBI ]
CGAP (NCI)Hs.655672
Alternative Splicing : Fast-db (Paris)GSHG0004058
Alternative Splicing GalleryENSG00000128805
Gene ExpressionARHGAP22 [ NCBI-GEO ]     ARHGAP22 [ SEEK ]   ARHGAP22 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5H3 (Uniprot)
NextProtQ7Z5H3  [Medical]
With graphics : InterProQ7Z5H3
Splice isoforms : SwissVarQ7Z5H3 (Swissvar)
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    RHOGAP (PS50238)   
Domains : Interpro (EBI)PH_like_dom    Pleckstrin_homology    Rho_GTPase_activation_prot    RhoGAP_dom   
Related proteins : CluSTrQ7Z5H3
Domain families : Pfam (Sanger)PH (PF00169)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00169    pfam00620   
Domain families : Smart (EMBL)PH (SM00233)  RhoGAP (SM00324)  
DMDM Disease mutations58504
Blocks (Seattle)Q7Z5H3
Human Protein AtlasENSG00000128805
Peptide AtlasQ7Z5H3
HPRD12476
IPIIPI00644736   IPI00009685   IPI00941482   IPI01015479   IPI00644168   IPI00967309   IPI00964603   IPI00829760   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5H3
IntAct (EBI)Q7Z5H3
FunCoupENSG00000128805
BioGRIDARHGAP22
IntegromeDBARHGAP22
STRING (EMBL)ARHGAP22
Ontologies - Pathways
QuickGOQ7Z5H3
Ontology : AmiGOangiogenesis  GTPase activator activity  protein binding  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  small GTPase mediated signal transduction  cell differentiation  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBIangiogenesis  GTPase activator activity  protein binding  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  small GTPase mediated signal transduction  cell differentiation  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  
Protein Interaction DatabaseARHGAP22
DoCM (Curated mutations)ARHGAP22
Wikipedia pathwaysARHGAP22
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerARHGAP22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGAP22
dbVarARHGAP22
ClinVarARHGAP22
1000_GenomesARHGAP22 
Exome Variant ServerARHGAP22
SNP (GeneSNP Utah)ARHGAP22
SNP : HGBaseARHGAP22
Genetic variants : HAPMAPARHGAP22
Genomic VariantsARHGAP22  ARHGAP22 [DGVbeta]
Mutations
ICGC Data PortalENSG00000128805 
Somatic Mutations in Cancer : COSMICARHGAP22 
CONAN: Copy Number AnalysisARHGAP22 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)10:49654068-49813176
Mutations and Diseases : HGMDARHGAP22
OMIM610585   
MedgenARHGAP22
NextProtQ7Z5H3 [Medical]
GENETestsARHGAP22
Disease Genetic AssociationARHGAP22
Huge Navigator ARHGAP22 [HugePedia]  ARHGAP22 [HugeCancerGEM]
snp3D : Map Gene to Disease58504
DGIdb (Drug Gene Interaction db)ARHGAP22
General knowledge
Homologs : HomoloGeneARHGAP22
Homology/Alignments : Family Browser (UCSC)ARHGAP22
Phylogenetic Trees/Animal Genes : TreeFamARHGAP22
Chemical/Protein Interactions : CTD58504
Chemical/Pharm GKB GenePA134979724
Clinical trialARHGAP22
Cancer Resource (Charite)ENSG00000128805
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
CoreMineARHGAP22
GoPubMedARHGAP22
iHOPARHGAP22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 20:12:18 CET 2014
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