Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ARHGAP23 (Rho GTPase activating protein 23)

Identity

Alias_symbol (synonym)KIAA1501
Other alias-
HGNC (Hugo) ARHGAP23
LocusID (NCBI) 57636
Atlas_Id 43139
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 38428476 and ends at 38512392 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AC040934.1 () / ARHGAP23 (17q12)ARHGAP23 (17q12) / ASIC2 (17q11.2)ARHGAP23 (17q12) / KLK6 (19q13.41)
ARHGAP23 (17q12) / TEX14 (17q22)MED1 (17q12) / ARHGAP23 (17q12)AC040934.1 ARHGAP23 17q12
ARHGAP23 17q12 ACCN1ARHGAP23 17q12 / TEX14 17q22MED1 17q12 / ARHGAP23 17q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGAP23   29293
Cards
Entrez_Gene (NCBI)ARHGAP23  57636  Rho GTPase activating protein 23
Aliases
GeneCards (Weizmann)ARHGAP23
Ensembl hg19 (Hinxton)ENSG00000275832 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000275832 [Gene_View]  chr17:38428476-38512392 [Contig_View]  ARHGAP23 [Vega]
ICGC DataPortalENSG00000275832
TCGA cBioPortalARHGAP23
AceView (NCBI)ARHGAP23
Genatlas (Paris)ARHGAP23
WikiGenes57636
SOURCE (Princeton)ARHGAP23
Genetics Home Reference (NIH)ARHGAP23
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGAP23  -     chr17:38428476-38512392 +  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGAP23  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblARHGAP23 - 17q12 [CytoView hg19]  ARHGAP23 - 17q12 [CytoView hg38]
Mapping of homologs : NCBIARHGAP23 [Mapview hg19]  ARHGAP23 [Mapview hg38]
OMIM610590   
Gene and transcription
Genbank (Entrez)AB040934 BC039190 BM548592 BY795315 CN429246
RefSeq transcript (Entrez)NM_001199417 NM_020876
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_187614
Consensus coding sequences : CCDS (NCBI)ARHGAP23
Cluster EST : UnigeneHs.374446 [ NCBI ]
CGAP (NCI)Hs.374446
Alternative Splicing GalleryENSG00000275832
Gene ExpressionARHGAP23 [ NCBI-GEO ]   ARHGAP23 [ EBI - ARRAY_EXPRESS ]   ARHGAP23 [ SEEK ]   ARHGAP23 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGAP23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57636
GTEX Portal (Tissue expression)ARHGAP23
Human Protein AtlasENSG00000275832-ARHGAP23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P227   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P227  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P227
Splice isoforms : SwissVarQ9P227
PhosPhoSitePlusQ9P227
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)    PH_DOMAIN (PS50003)    RHOGAP (PS50238)   
Domains : Interpro (EBI)PDZ    PH_dom-like    PH_domain    Rho_GTPase_activation_prot    RhoGAP_dom   
Domain families : Pfam (Sanger)PDZ (PF00595)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00595    pfam00620   
Domain families : Smart (EMBL)PDZ (SM00228)  PH (SM00233)  RhoGAP (SM00324)  
Conserved Domain (NCBI)ARHGAP23
DMDM Disease mutations57636
Blocks (Seattle)ARHGAP23
SuperfamilyQ9P227
Human Protein Atlas [tissue]ENSG00000275832-ARHGAP23 [tissue]
Peptide AtlasQ9P227
IPIIPI00101969   IPI00887362   IPI00942873   IPI01021559   IPI01021377   IPI01021542   
Protein Interaction databases
DIP (DOE-UCLA)Q9P227
IntAct (EBI)Q9P227
FunCoupENSG00000275832
BioGRIDARHGAP23
STRING (EMBL)ARHGAP23
ZODIACARHGAP23
Ontologies - Pathways
QuickGOQ9P227
Ontology : AmiGOGTPase activator activity  GTPase activator activity  cytosol  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  extracellular exosome  
Ontology : EGO-EBIGTPase activator activity  GTPase activator activity  cytosol  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  extracellular exosome  
NDEx NetworkARHGAP23
Atlas of Cancer Signalling NetworkARHGAP23
Wikipedia pathwaysARHGAP23
Orthology - Evolution
OrthoDB57636
GeneTree (enSembl)ENSG00000275832
Phylogenetic Trees/Animal Genes : TreeFamARHGAP23
HOVERGENQ9P227
HOGENOMQ9P227
Homologs : HomoloGeneARHGAP23
Homology/Alignments : Family Browser (UCSC)ARHGAP23
Gene fusions - Rearrangements
Fusion: TCGA_MDACCAC040934.1 ARHGAP23 17q12 BRCA
Fusion: TCGA_MDACCARHGAP23 17q12 ACCN1 BRCA
Fusion: TCGA_MDACCARHGAP23 17q12 TEX14 17q22 BRCA
Fusion: TCGA_MDACCMED1 17q12 ARHGAP23 17q12 BRCA
Tumor Fusion PortalARHGAP23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGAP23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGAP23
dbVarARHGAP23
ClinVarARHGAP23
1000_GenomesARHGAP23 
Exome Variant ServerARHGAP23
ExAC (Exome Aggregation Consortium)ENSG00000275832
GNOMAD BrowserENSG00000275832
Genetic variants : HAPMAP57636
Genomic Variants (DGV)ARHGAP23 [DGVbeta]
DECIPHERARHGAP23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGAP23 
Mutations
ICGC Data PortalARHGAP23 
TCGA Data PortalARHGAP23 
Broad Tumor PortalARHGAP23
OASIS PortalARHGAP23 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDARHGAP23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGAP23
DgiDB (Drug Gene Interaction Database)ARHGAP23
DoCM (Curated mutations)ARHGAP23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGAP23 (select a term)
intoGenARHGAP23
Cancer3DARHGAP23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610590   
Orphanet
DisGeNETARHGAP23
MedgenARHGAP23
Genetic Testing Registry ARHGAP23
NextProtQ9P227 [Medical]
TSGene57636
GENETestsARHGAP23
Target ValidationARHGAP23
Huge Navigator ARHGAP23 [HugePedia]
snp3D : Map Gene to Disease57636
BioCentury BCIQARHGAP23
ClinGenARHGAP23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57636
Chemical/Pharm GKB GenePA134891853
Clinical trialARHGAP23
Miscellaneous
canSAR (ICR)ARHGAP23 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGAP23
EVEXARHGAP23
GoPubMedARHGAP23
iHOPARHGAP23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:34 CET 2017

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