Identity
HGNC
LOCATION
4q21.23
LOCUSID
ALIAS
FILGAP,RC-GAP72,RCGAP72,p73,p73RhoGAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83478
MIM: 610586
HGNC: 25361
Ensembl: ENSG00000138639
Variants:
dbSNP: 83478
ClinVar: 83478
TCGA: ENSG00000138639
COSMIC: ARHGAP24
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38742566 | 2024 | Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis. | 0 |
| 38742566 | 2024 | Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis. | 0 |
| 38065968 | 2023 | FilGAP regulates tumor growth in Glioma through the regulation of mTORC1 and mTORC2. | 1 |
| 38065968 | 2023 | FilGAP regulates tumor growth in Glioma through the regulation of mTORC1 and mTORC2. | 1 |
| 36168627 | 2022 | ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold. | 7 |
| 36168627 | 2022 | ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold. | 7 |
| 33710706 | 2021 | FilGAP, a GAP protein for Rac, regulates front-rear polarity and tumor cell migration through the ECM. | 5 |
| 33710706 | 2021 | FilGAP, a GAP protein for Rac, regulates front-rear polarity and tumor cell migration through the ECM. | 5 |
| 31430374 | 2020 | ARHGAP24 inhibits cell proliferation and cell cycle progression and induces apoptosis of lung cancer via a STAT6-WWP2-p27 axis. | 19 |
| 31785816 | 2020 | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | 7 |
| 31935390 | 2020 | HOTAIRM1 suppresses cell proliferation and invasion in ovarian cancer through facilitating ARHGAP24 expression by sponging miR-106a-5p. | 23 |
| 31430374 | 2020 | ARHGAP24 inhibits cell proliferation and cell cycle progression and induces apoptosis of lung cancer via a STAT6-WWP2-p27 axis. | 19 |
| 31785816 | 2020 | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | 7 |
| 31935390 | 2020 | HOTAIRM1 suppresses cell proliferation and invasion in ovarian cancer through facilitating ARHGAP24 expression by sponging miR-106a-5p. | 23 |
| 30599132 | 2019 | Rho GTPase Activating Protein 24 (ARHGAP24) Silencing Promotes Lung Cancer Cell Migration and Invasion by Activating β-Catenin Signaling. | 9 |
Citation
Dessen P
ARHGAP24 (Rho GTPase activating protein 24)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/695/arhgap24
