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ARHGAP27 (Rho GTPase activating protein 27)

Identity

Alias_namesSH3D20
SH3 domain containing 20
Alias_symbol (synonym)CAMGAP1
FLJ43547
SH3P20
Other aliasPP905
HGNC (Hugo) ARHGAP27
LocusID (NCBI) 201176
Atlas_Id 60463
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 43471268 and ends at 43507663 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SORBS2 (4q35.1) / ARHGAP27 (17q21.31)TOR1B (9q34.11) / ARHGAP27 (17q21.31)TOR1B ARHGAP27
SORBS ARHGAP27

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGAP27   31813
Cards
Entrez_Gene (NCBI)ARHGAP27  201176  Rho GTPase activating protein 27
AliasesCAMGAP1; PP905; SH3D20; SH3P20
GeneCards (Weizmann)ARHGAP27
Ensembl hg19 (Hinxton)ENSG00000159314 [Gene_View]  chr17:43471268-43507663 [Contig_View]  ARHGAP27 [Vega]
Ensembl hg38 (Hinxton)ENSG00000159314 [Gene_View]  chr17:43471268-43507663 [Contig_View]  ARHGAP27 [Vega]
ICGC DataPortalENSG00000159314
TCGA cBioPortalARHGAP27
AceView (NCBI)ARHGAP27
Genatlas (Paris)ARHGAP27
WikiGenes201176
SOURCE (Princeton)ARHGAP27
Genetics Home Reference (NIH)ARHGAP27
Genomic and cartography
GoldenPath hg19 (UCSC)ARHGAP27  -     chr17:43471268-43507663 -  17q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARHGAP27  -     17q21.31   [Description]    (hg38-Dec_2013)
EnsemblARHGAP27 - 17q21.31 [CytoView hg19]  ARHGAP27 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIARHGAP27 [Mapview hg19]  ARHGAP27 [Mapview hg38]
OMIM610591   
Gene and transcription
Genbank (Entrez)AF258593 AK092891 AK125535 AK290650 AK300880
RefSeq transcript (Entrez)NM_001159330 NM_001282290 NM_174919 NM_199282
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NT_167251 NT_187663 NW_004929407
Consensus coding sequences : CCDS (NCBI)ARHGAP27
Cluster EST : UnigeneHs.205326 [ NCBI ]
CGAP (NCI)Hs.205326
Alternative Splicing GalleryENSG00000159314
Gene ExpressionARHGAP27 [ NCBI-GEO ]   ARHGAP27 [ EBI - ARRAY_EXPRESS ]   ARHGAP27 [ SEEK ]   ARHGAP27 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGAP27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201176
GTEX Portal (Tissue expression)ARHGAP27
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZUM4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZUM4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZUM4
Splice isoforms : SwissVarQ6ZUM4
PhosPhoSitePlusQ6ZUM4
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    RHOGAP (PS50238)    SH3 (PS50002)    WW_DOMAIN_2 (PS50020)   
Domains : Interpro (EBI)PH_domain    PH_like_dom    Quinonprotein_ADH-like_supfam    Rho_GTPase_act    Rho_GTPase_activation_prot    RhoGAP_dom    SH3_domain    WW_dom   
Domain families : Pfam (Sanger)PH (PF00169)    RhoGAP (PF00620)    WW (PF00397)   
Domain families : Pfam (NCBI)pfam00169    pfam00620    pfam00397   
Domain families : Smart (EMBL)PH (SM00233)  RhoGAP (SM00324)  SH3 (SM00326)  WW (SM00456)  
Conserved Domain (NCBI)ARHGAP27
DMDM Disease mutations201176
Blocks (Seattle)ARHGAP27
PDB (SRS)3PP2   
PDB (PDBSum)3PP2   
PDB (IMB)3PP2   
PDB (RSDB)3PP2   
Structural Biology KnowledgeBase3PP2   
SCOP (Structural Classification of Proteins)3PP2   
CATH (Classification of proteins structures)3PP2   
SuperfamilyQ6ZUM4
Human Protein AtlasENSG00000159314
Peptide AtlasQ6ZUM4
HPRD12477
IPIIPI00885078   IPI00398170   IPI00885118   IPI00884998   IPI00816399   IPI01011796   IPI00979747   IPI00983933   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZUM4
IntAct (EBI)Q6ZUM4
FunCoupENSG00000159314
BioGRIDARHGAP27
STRING (EMBL)ARHGAP27
ZODIACARHGAP27
Ontologies - Pathways
QuickGOQ6ZUM4
Ontology : AmiGOGTPase activator activity  intracellular  cytoplasm  receptor-mediated endocytosis  signal transduction  membrane  SH3 domain binding  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  intracellular  cytoplasm  receptor-mediated endocytosis  signal transduction  membrane  SH3 domain binding  positive regulation of GTPase activity  
NDEx NetworkARHGAP27
Atlas of Cancer Signalling NetworkARHGAP27
Wikipedia pathwaysARHGAP27
Orthology - Evolution
OrthoDB201176
GeneTree (enSembl)ENSG00000159314
Phylogenetic Trees/Animal Genes : TreeFamARHGAP27
HOVERGENQ6ZUM4
HOGENOMQ6ZUM4
Homologs : HomoloGeneARHGAP27
Homology/Alignments : Family Browser (UCSC)ARHGAP27
Gene fusions - Rearrangements
Fusion: TCGATOR1B ARHGAP27
Fusion: TCGASORBS ARHGAP27
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGAP27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGAP27
dbVarARHGAP27
ClinVarARHGAP27
1000_GenomesARHGAP27 
Exome Variant ServerARHGAP27
ExAC (Exome Aggregation Consortium)ARHGAP27 (select the gene name)
Genetic variants : HAPMAP201176
Genomic Variants (DGV)ARHGAP27 [DGVbeta]
DECIPHER (Syndromes)17:43471268-43507663  ENSG00000159314
CONAN: Copy Number AnalysisARHGAP27 
Mutations
ICGC Data PortalARHGAP27 
TCGA Data PortalARHGAP27 
Broad Tumor PortalARHGAP27
OASIS PortalARHGAP27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGAP27  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARHGAP27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGAP27
DgiDB (Drug Gene Interaction Database)ARHGAP27
DoCM (Curated mutations)ARHGAP27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGAP27 (select a term)
intoGenARHGAP27
Cancer3DARHGAP27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610591   
Orphanet
MedgenARHGAP27
Genetic Testing Registry ARHGAP27
NextProtQ6ZUM4 [Medical]
TSGene201176
GENETestsARHGAP27
Huge Navigator ARHGAP27 [HugePedia]
snp3D : Map Gene to Disease201176
BioCentury BCIQARHGAP27
ClinGenARHGAP27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201176
Chemical/Pharm GKB GenePA134873327
Clinical trialARHGAP27
Miscellaneous
canSAR (ICR)ARHGAP27 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGAP27
EVEXARHGAP27
GoPubMedARHGAP27
iHOPARHGAP27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:51 CET 2017

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