Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARHGAP28 (Rho GTPase activating protein 28)

Identity

Alias_symbol (synonym)KIAA1314
FLJ10312
Other alias-
HGNC (Hugo) ARHGAP28
LocusID (NCBI) 79822
Atlas_Id 60464
Location 18p11.31  [Link to chromosome band 18p11]
Location_base_pair Starts at 6834433 and ends at 6915713 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGAP28   25509
Cards
Entrez_Gene (NCBI)ARHGAP28  79822  Rho GTPase activating protein 28
Aliases
GeneCards (Weizmann)ARHGAP28
Ensembl hg19 (Hinxton)ENSG00000088756 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000088756 [Gene_View]  chr18:6834433-6915713 [Contig_View]  ARHGAP28 [Vega]
ICGC DataPortalENSG00000088756
TCGA cBioPortalARHGAP28
AceView (NCBI)ARHGAP28
Genatlas (Paris)ARHGAP28
WikiGenes79822
SOURCE (Princeton)ARHGAP28
Genetics Home Reference (NIH)ARHGAP28
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGAP28  -     chr18:6834433-6915713 +  18p11.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGAP28  -     18p11.31   [Description]    (hg19-Feb_2009)
EnsemblARHGAP28 - 18p11.31 [CytoView hg19]  ARHGAP28 - 18p11.31 [CytoView hg38]
Mapping of homologs : NCBIARHGAP28 [Mapview hg19]  ARHGAP28 [Mapview hg38]
OMIM610592   
Gene and transcription
Genbank (Entrez)AB037735 AI435330 AK001174 AK024298 AK130670
RefSeq transcript (Entrez)NM_001010000 NM_030672
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGAP28
Cluster EST : UnigeneHs.183114 [ NCBI ]
CGAP (NCI)Hs.183114
Alternative Splicing GalleryENSG00000088756
Gene ExpressionARHGAP28 [ NCBI-GEO ]   ARHGAP28 [ EBI - ARRAY_EXPRESS ]   ARHGAP28 [ SEEK ]   ARHGAP28 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGAP28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79822
GTEX Portal (Tissue expression)ARHGAP28
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2N2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2N2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2N2
Splice isoforms : SwissVarQ9P2N2
PhosPhoSitePlusQ9P2N2
Domaine pattern : Prosite (Expaxy)RHOGAP (PS50238)   
Domains : Interpro (EBI)Rho_GTPase_activation_prot    RhoGAP_dom   
Domain families : Pfam (Sanger)RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00620   
Domain families : Smart (EMBL)RhoGAP (SM00324)  
Conserved Domain (NCBI)ARHGAP28
DMDM Disease mutations79822
Blocks (Seattle)ARHGAP28
SuperfamilyQ9P2N2
Human Protein AtlasENSG00000088756
Peptide AtlasQ9P2N2
HPRD10961
IPIIPI00296793   IPI00877164   IPI00877155   IPI01014949   IPI00977548   IPI01015837   IPI00976893   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2N2
IntAct (EBI)Q9P2N2
FunCoupENSG00000088756
BioGRIDARHGAP28
STRING (EMBL)ARHGAP28
ZODIACARHGAP28
Ontologies - Pathways
QuickGOQ9P2N2
Ontology : AmiGOGTPase activator activity  cytosol  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  negative regulation of stress fiber assembly  negative regulation of GTP binding  
Ontology : EGO-EBIGTPase activator activity  cytosol  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  negative regulation of stress fiber assembly  negative regulation of GTP binding  
NDEx NetworkARHGAP28
Atlas of Cancer Signalling NetworkARHGAP28
Wikipedia pathwaysARHGAP28
Orthology - Evolution
OrthoDB79822
GeneTree (enSembl)ENSG00000088756
Phylogenetic Trees/Animal Genes : TreeFamARHGAP28
HOVERGENQ9P2N2
HOGENOMQ9P2N2
Homologs : HomoloGeneARHGAP28
Homology/Alignments : Family Browser (UCSC)ARHGAP28
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGAP28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGAP28
dbVarARHGAP28
ClinVarARHGAP28
1000_GenomesARHGAP28 
Exome Variant ServerARHGAP28
ExAC (Exome Aggregation Consortium)ARHGAP28 (select the gene name)
Genetic variants : HAPMAP79822
Genomic Variants (DGV)ARHGAP28 [DGVbeta]
DECIPHERARHGAP28 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGAP28 
Mutations
ICGC Data PortalARHGAP28 
TCGA Data PortalARHGAP28 
Broad Tumor PortalARHGAP28
OASIS PortalARHGAP28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGAP28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARHGAP28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGAP28
DgiDB (Drug Gene Interaction Database)ARHGAP28
DoCM (Curated mutations)ARHGAP28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGAP28 (select a term)
intoGenARHGAP28
Cancer3DARHGAP28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610592   
Orphanet
MedgenARHGAP28
Genetic Testing Registry ARHGAP28
NextProtQ9P2N2 [Medical]
TSGene79822
GENETestsARHGAP28
Target ValidationARHGAP28
Huge Navigator ARHGAP28 [HugePedia]
snp3D : Map Gene to Disease79822
BioCentury BCIQARHGAP28
ClinGenARHGAP28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79822
Chemical/Pharm GKB GenePA134915320
Clinical trialARHGAP28
Miscellaneous
canSAR (ICR)ARHGAP28 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGAP28
EVEXARHGAP28
GoPubMedARHGAP28
iHOPARHGAP28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:38:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.