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ARHGAP39 (Rho GTPase activating protein 39)

Identity

Alias (NCBI)CrGAP
Vilse
HGNC (Hugo) ARHGAP39
HGNC Alias symbKIAA1688
Vilse
CrGAP
HGNC Alias nameRhoGAP93B homolog (Drosophila)
 crossGAP homolog (Drosophila)
LocusID (NCBI) 80728
Atlas_Id 60470
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 144529179 and ends at 144605695 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
USP32 (17q23.1) / ARHGAP39 (8q24.3)VPS8 (3q27.2) / ARHGAP39 (8q24.3)USP32 ARHGAP39
VPS8 ARHGAP39

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(3;8)(q27;q24) VPS8/ARHGAP39
t(8;17)(q24;q23) USP32/ARHGAP39


External links

Nomenclature
HGNC (Hugo)ARHGAP39   29351
Cards
Entrez_Gene (NCBI)ARHGAP39  80728  Rho GTPase activating protein 39
AliasesCrGAP; Vilse
GeneCards (Weizmann)ARHGAP39
Ensembl hg19 (Hinxton)ENSG00000147799 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147799 [Gene_View]  ENSG00000147799 [Sequence]  chr8:144529179-144605695 [Contig_View]  ARHGAP39 [Vega]
ICGC DataPortalENSG00000147799
TCGA cBioPortalARHGAP39
AceView (NCBI)ARHGAP39
Genatlas (Paris)ARHGAP39
WikiGenes80728
SOURCE (Princeton)ARHGAP39
Genetics Home Reference (NIH)ARHGAP39
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGAP39  -     chr8:144529179-144605695 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGAP39  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathARHGAP39 - 8q24.3 [CytoView hg19]  ARHGAP39 - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000147799
genome Data Viewer NCBIARHGAP39 [Mapview hg19]  
OMIM615880   
Gene and transcription
Genbank (Entrez)AB051475 AK092501 AK296353 AK303851 BC013071
RefSeq transcript (Entrez)NM_001308207 NM_001308208 NM_025251
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGAP39
Alternative Splicing GalleryENSG00000147799
Gene ExpressionARHGAP39 [ NCBI-GEO ]   ARHGAP39 [ EBI - ARRAY_EXPRESS ]   ARHGAP39 [ SEEK ]   ARHGAP39 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGAP39 [ Firebrowse - Broad ]
GenevisibleExpression of ARHGAP39 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80728
GTEX Portal (Tissue expression)ARHGAP39
Human Protein AtlasENSG00000147799-ARHGAP39 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0H5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0H5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0H5
Splice isoforms : SwissVarQ9C0H5
PhosPhoSitePlusQ9C0H5
Domaine pattern : Prosite (Expaxy)MYTH4 (PS51016)    RHOGAP (PS50238)    WW_DOMAIN_2 (PS50020)   
Domains : Interpro (EBI)MyTH4_dom    MyTH4_dom_sf    Rho_GTPase_activation_prot    RhoGAP_dom    WW_dom    WW_dom_sf   
Domain families : Pfam (Sanger)MyTH4 (PF00784)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00784    pfam00620   
Domain families : Smart (EMBL)MyTH4 (SM00139)  RhoGAP (SM00324)  WW (SM00456)  
Conserved Domain (NCBI)ARHGAP39
DMDM Disease mutations80728
Blocks (Seattle)ARHGAP39
SuperfamilyQ9C0H5
Human Protein Atlas [tissue]ENSG00000147799-ARHGAP39 [tissue]
Peptide AtlasQ9C0H5
HPRD17224
IPIIPI00747986   IPI00455851   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0H5
IntAct (EBI)Q9C0H5
FunCoupENSG00000147799
BioGRIDARHGAP39
STRING (EMBL)ARHGAP39
ZODIACARHGAP39
Ontologies - Pathways
QuickGOQ9C0H5
Ontology : AmiGOGTPase activator activity  nucleus  cytoplasm  cytosol  cytoskeleton  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  glutamatergic synapse  glutamatergic synapse  postsynapse organization  postsynapse organization  
Ontology : EGO-EBIGTPase activator activity  nucleus  cytoplasm  cytosol  cytoskeleton  signal transduction  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  glutamatergic synapse  glutamatergic synapse  postsynapse organization  postsynapse organization  
NDEx NetworkARHGAP39
Atlas of Cancer Signalling NetworkARHGAP39
Wikipedia pathwaysARHGAP39
Orthology - Evolution
OrthoDB80728
GeneTree (enSembl)ENSG00000147799
Phylogenetic Trees/Animal Genes : TreeFamARHGAP39
HOGENOMQ9C0H5
Homologs : HomoloGeneARHGAP39
Homology/Alignments : Family Browser (UCSC)ARHGAP39
Gene fusions - Rearrangements
Fusion PortalUSP32 ARHGAP39
Fusion PortalVPS8 ARHGAP39
Fusion : QuiverARHGAP39
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGAP39 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGAP39
dbVarARHGAP39
ClinVarARHGAP39
1000_GenomesARHGAP39 
Exome Variant ServerARHGAP39
GNOMAD BrowserENSG00000147799
Varsome BrowserARHGAP39
Genetic variants : HAPMAP80728
Genomic Variants (DGV)ARHGAP39 [DGVbeta]
DECIPHERARHGAP39 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGAP39 
Mutations
ICGC Data PortalARHGAP39 
TCGA Data PortalARHGAP39 
Broad Tumor PortalARHGAP39
OASIS PortalARHGAP39 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGAP39  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DARHGAP39
Mutations and Diseases : HGMDARHGAP39
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGAP39
DgiDB (Drug Gene Interaction Database)ARHGAP39
DoCM (Curated mutations)ARHGAP39 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGAP39 (select a term)
intoGenARHGAP39
Cancer3DARHGAP39(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615880   
Orphanet
DisGeNETARHGAP39
MedgenARHGAP39
Genetic Testing Registry ARHGAP39
NextProtQ9C0H5 [Medical]
TSGene80728
GENETestsARHGAP39
Target ValidationARHGAP39
Huge Navigator ARHGAP39 [HugePedia]
snp3D : Map Gene to Disease80728
BioCentury BCIQARHGAP39
ClinGenARHGAP39
Clinical trials, drugs, therapy
Protein Interactions : CTD80728
Pharm GKB GenePA165585391
Clinical trialARHGAP39
Miscellaneous
canSAR (ICR)ARHGAP39 (select the gene name)
HarmonizomeARHGAP39
DataMed IndexARHGAP39
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGAP39
EVEXARHGAP39
GoPubMedARHGAP39
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Aug 22 19:05:54 CEST 2020

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