ARHGAP44 (Rho GTPase activating protein 44)

2018-07-01  

Identity

HGNC
LOCATION
17p12
LOCUSID
ALIAS
NPC-A-10,RICH2
FUSION GENES

Other Information

Locus ID:

NCBI: 9912
MIM: 617716
HGNC: 29096
Ensembl: ENSG00000006740

Variants:

dbSNP: 9912
ClinVar: 9912
TCGA: ENSG00000006740
COSMIC: ARHGAP44

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006740ENST00000262444E7ERK8
ENSG00000006740ENST00000340825Q17R89
ENSG00000006740ENST00000379672Q17R89
ENSG00000006740ENST00000544416F5H6L3
ENSG00000006740ENST00000580768J3KRS3
ENSG00000006740ENST00000581437K7EK86
ENSG00000006740ENST00000583608J3QQU7
ENSG00000006740ENST00000616670A0A087WZS3

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192736152009A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.71
114314732001Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1.39
211072682011Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS.13
285271132017Mutant p53 promotes cell spreading and migration via ARHGAP44.1
280694462017RICH2 is implicated in viraemic control of HIV-1 in black South African individuals.0
311369842019RICH2, a potential tumor suppressor in hepatocellular carcinoma.0

Citation

Dessen P

ARHGAP44 (Rho GTPase activating protein 44)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57539/arhgap44