ARHGEF19 (Rho guanine nucleotide exchange factor 19)

2006-10-01  

Identity

HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
WGEF
FUSION GENES

Other Information

Locus ID:

NCBI: 128272
MIM: 612496
HGNC: 26604
Ensembl: ENSG00000142632

Variants:

dbSNP: 128272
ClinVar: 128272
TCGA: ENSG00000142632
COSMIC: ARHGEF19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142632ENST00000270747Q8IW93
ENSG00000142632ENST00000441785Q5TEV0
ENSG00000142632ENST00000449495H0Y4D8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signalling by NGFREACTOMER-HSA-166520
p75 NTR receptor-mediated signallingREACTOMER-HSA-193704
Cell death signalling via NRAGE, NRIF and NADEREACTOMER-HSA-204998
NRAGE signals death through JNKREACTOMER-HSA-193648
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (12/13) signalling eventsREACTOMER-HSA-416482

References

Pubmed IDYearTitleCitations
244056102014miR-503 regulates metastatic function through Rho guanine nucleotide exchanger factor 19 in hepatocellular carcinoma.11
291646152018ARHGEF19 interacts with BRAF to activate MAPK signaling during the tumorigenesis of non-small cell lung cancer.4

Citation

Dessen P

ARHGEF19 (Rho guanine nucleotide exchange factor 19)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43149/arhgef19