Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ARHGEF26 (Rho guanine nucleotide exchange factor 26)

Identity

Alias_namesRho guanine nucleotide exchange factor (GEF) 26
Alias_symbol (synonym)DKFZP434D146
SGEF
Other aliasCSGEF
HMFN1864
HGNC (Hugo) ARHGEF26
LocusID (NCBI) 26084
Atlas_Id 42280
Location 3q25.2  [Link to chromosome band 3q25]
Location_base_pair Starts at 154121003 and ends at 154257827 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANOS1 (Xp22.31) / ARHGEF26 (3q25.2)CAPNS1 (19q13.12) / ARHGEF26 (3q25.2)COL3A1 (2q32.2) / ARHGEF26 (3q25.2)
CAPNS1 19q13.12 / ARHGEF26 3q25.2KAL1 ARHGEF26 3q25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGEF26   24490
Cards
Entrez_Gene (NCBI)ARHGEF26  26084  Rho guanine nucleotide exchange factor 26
AliasesCSGEF; HMFN1864; SGEF
GeneCards (Weizmann)ARHGEF26
Ensembl hg19 (Hinxton)ENSG00000114790 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114790 [Gene_View]  chr3:154121003-154257827 [Contig_View]  ARHGEF26 [Vega]
ICGC DataPortalENSG00000114790
TCGA cBioPortalARHGEF26
AceView (NCBI)ARHGEF26
Genatlas (Paris)ARHGEF26
WikiGenes26084
SOURCE (Princeton)ARHGEF26
Genetics Home Reference (NIH)ARHGEF26
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF26  -     chr3:154121003-154257827 +  3q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF26  -     3q25.2   [Description]    (hg19-Feb_2009)
EnsemblARHGEF26 - 3q25.2 [CytoView hg19]  ARHGEF26 - 3q25.2 [CytoView hg38]
Mapping of homologs : NCBIARHGEF26 [Mapview hg19]  ARHGEF26 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB073386 AF415175 AF415176 AK022655 AK022884
RefSeq transcript (Entrez)NM_001251962 NM_001251963 NM_015595
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_030405 NT_187533
Consensus coding sequences : CCDS (NCBI)ARHGEF26
Cluster EST : UnigeneHs.240845 [ NCBI ]
CGAP (NCI)Hs.240845
Alternative Splicing GalleryENSG00000114790
Gene ExpressionARHGEF26 [ NCBI-GEO ]   ARHGEF26 [ EBI - ARRAY_EXPRESS ]   ARHGEF26 [ SEEK ]   ARHGEF26 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF26 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26084
GTEX Portal (Tissue expression)ARHGEF26
Human Protein AtlasENSG00000114790-ARHGEF26 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DR7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DR7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DR7
Splice isoforms : SwissVarQ96DR7
PhosPhoSitePlusQ96DR7
Domaine pattern : Prosite (Expaxy)DH_2 (PS50010)    PH_DOMAIN (PS50003)    SH3 (PS50002)   
Domains : Interpro (EBI)DH-domain    PH_dom-like    PH_domain    SH3_domain   
Domain families : Pfam (Sanger)RhoGEF (PF00621)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00621    pfam14604   
Domain families : Smart (EMBL)PH (SM00233)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)ARHGEF26
DMDM Disease mutations26084
Blocks (Seattle)ARHGEF26
SuperfamilyQ96DR7
Human Protein Atlas [tissue]ENSG00000114790-ARHGEF26 [tissue]
Peptide AtlasQ96DR7
HPRD11554
IPIIPI00465146   IPI00885123   IPI00966363   
Protein Interaction databases
DIP (DOE-UCLA)Q96DR7
IntAct (EBI)Q96DR7
FunCoupENSG00000114790
BioGRIDARHGEF26
STRING (EMBL)ARHGEF26
ZODIACARHGEF26
Ontologies - Pathways
QuickGOQ96DR7
Ontology : AmiGOruffle  endothelial cell morphogenesis  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  cytosol  regulation of Rho protein signal transduction  positive regulation of apoptotic process  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  ruffle assembly  
Ontology : EGO-EBIruffle  endothelial cell morphogenesis  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  cytosol  regulation of Rho protein signal transduction  positive regulation of apoptotic process  positive regulation of GTPase activity  regulation of small GTPase mediated signal transduction  ruffle assembly  
Pathways : KEGGBacterial invasion of epithelial cells   
NDEx NetworkARHGEF26
Atlas of Cancer Signalling NetworkARHGEF26
Wikipedia pathwaysARHGEF26
Orthology - Evolution
OrthoDB26084
GeneTree (enSembl)ENSG00000114790
Phylogenetic Trees/Animal Genes : TreeFamARHGEF26
HOVERGENQ96DR7
HOGENOMQ96DR7
Homologs : HomoloGeneARHGEF26
Homology/Alignments : Family Browser (UCSC)ARHGEF26
Gene fusions - Rearrangements
Fusion : MitelmanANOS1/ARHGEF26 [Xp22.31/3q25.2]  [t(X;3)(p22;q25)]  
Fusion : MitelmanCAPNS1/ARHGEF26 [19q13.12/3q25.2]  [t(3;19)(q25;q13)]  
Fusion: TCGA_MDACCCAPNS1 19q13.12 ARHGEF26 3q25.2 PRAD
Fusion: TCGA_MDACCKAL1 ARHGEF26 3q25.2 BRCA
Tumor Fusion PortalARHGEF26
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGEF26 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGEF26
dbVarARHGEF26
ClinVarARHGEF26
1000_GenomesARHGEF26 
Exome Variant ServerARHGEF26
ExAC (Exome Aggregation Consortium)ENSG00000114790
GNOMAD BrowserENSG00000114790
Genetic variants : HAPMAP26084
Genomic Variants (DGV)ARHGEF26 [DGVbeta]
DECIPHERARHGEF26 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGEF26 
Mutations
ICGC Data PortalARHGEF26 
TCGA Data PortalARHGEF26 
Broad Tumor PortalARHGEF26
OASIS PortalARHGEF26 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGEF26  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARHGEF26
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGEF26
DgiDB (Drug Gene Interaction Database)ARHGEF26
DoCM (Curated mutations)ARHGEF26 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGEF26 (select a term)
intoGenARHGEF26
Cancer3DARHGEF26(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETARHGEF26
MedgenARHGEF26
Genetic Testing Registry ARHGEF26
NextProtQ96DR7 [Medical]
TSGene26084
GENETestsARHGEF26
Target ValidationARHGEF26
Huge Navigator ARHGEF26 [HugePedia]
snp3D : Map Gene to Disease26084
BioCentury BCIQARHGEF26
ClinGenARHGEF26
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26084
Chemical/Pharm GKB GenePA166048961
Clinical trialARHGEF26
Miscellaneous
canSAR (ICR)ARHGEF26 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGEF26
EVEXARHGEF26
GoPubMedARHGEF26
iHOPARHGEF26
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:40 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.