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ARHGEF37 (Rho guanine nucleotide exchange factor 37)

Identity

Alias_namesRho guanine nucleotide exchange factor (GEF) 37
Alias_symbol (synonym)FLJ41603
Other alias-
HGNC (Hugo) ARHGEF37
LocusID (NCBI) 389337
Atlas_Id 60479
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 149581572 and ends at 149634964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARHGEF37 (5q32) / ARHGEF37 (5q32)ARHGEF37 (5q32) / DIRC3 (2q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGEF37   34430
Cards
Entrez_Gene (NCBI)ARHGEF37  389337  Rho guanine nucleotide exchange factor 37
Aliases
GeneCards (Weizmann)ARHGEF37
Ensembl hg19 (Hinxton)ENSG00000183111 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183111 [Gene_View]  chr5:149581572-149634964 [Contig_View]  ARHGEF37 [Vega]
ICGC DataPortalENSG00000183111
TCGA cBioPortalARHGEF37
AceView (NCBI)ARHGEF37
Genatlas (Paris)ARHGEF37
WikiGenes389337
SOURCE (Princeton)ARHGEF37
Genetics Home Reference (NIH)ARHGEF37
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF37  -     chr5:149581572-149634964 +  5q32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF37  -     5q32   [Description]    (hg19-Feb_2009)
EnsemblARHGEF37 - 5q32 [CytoView hg19]  ARHGEF37 - 5q32 [CytoView hg38]
Mapping of homologs : NCBIARHGEF37 [Mapview hg19]  ARHGEF37 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB199796 AK023814 AK123597 AK300355 AK300559
RefSeq transcript (Entrez)NM_001001669
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGEF37
Cluster EST : UnigeneHs.256206 [ NCBI ]
CGAP (NCI)Hs.256206
Alternative Splicing GalleryENSG00000183111
Gene ExpressionARHGEF37 [ NCBI-GEO ]   ARHGEF37 [ EBI - ARRAY_EXPRESS ]   ARHGEF37 [ SEEK ]   ARHGEF37 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF37 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389337
GTEX Portal (Tissue expression)ARHGEF37
Protein : pattern, domain, 3D structure
UniProt/SwissProtA1IGU5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA1IGU5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA1IGU5
Splice isoforms : SwissVarA1IGU5
PhosPhoSitePlusA1IGU5
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    DH_2 (PS50010)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom    DH-domain    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)RhoGEF (PF00621)    SH3_1 (PF00018)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00621    pfam00018    pfam07653   
Domain families : Smart (EMBL)BAR (SM00721)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)ARHGEF37
DMDM Disease mutations389337
Blocks (Seattle)ARHGEF37
SuperfamilyA1IGU5
Human Protein AtlasENSG00000183111
Peptide AtlasA1IGU5
HPRD13454
IPIIPI00374285   IPI00979404   IPI00965898   
Protein Interaction databases
DIP (DOE-UCLA)A1IGU5
IntAct (EBI)A1IGU5
FunCoupENSG00000183111
BioGRIDARHGEF37
STRING (EMBL)ARHGEF37
ZODIACARHGEF37
Ontologies - Pathways
QuickGOA1IGU5
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  cytoplasm  small GTPase mediated signal transduction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  cytoplasm  small GTPase mediated signal transduction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
NDEx NetworkARHGEF37
Atlas of Cancer Signalling NetworkARHGEF37
Wikipedia pathwaysARHGEF37
Orthology - Evolution
OrthoDB389337
GeneTree (enSembl)ENSG00000183111
Phylogenetic Trees/Animal Genes : TreeFamARHGEF37
HOVERGENA1IGU5
HOGENOMA1IGU5
Homologs : HomoloGeneARHGEF37
Homology/Alignments : Family Browser (UCSC)ARHGEF37
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGEF37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGEF37
dbVarARHGEF37
ClinVarARHGEF37
1000_GenomesARHGEF37 
Exome Variant ServerARHGEF37
ExAC (Exome Aggregation Consortium)ARHGEF37 (select the gene name)
Genetic variants : HAPMAP389337
Genomic Variants (DGV)ARHGEF37 [DGVbeta]
DECIPHERARHGEF37 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGEF37 
Mutations
ICGC Data PortalARHGEF37 
TCGA Data PortalARHGEF37 
Broad Tumor PortalARHGEF37
OASIS PortalARHGEF37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGEF37  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARHGEF37
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGEF37
DgiDB (Drug Gene Interaction Database)ARHGEF37
DoCM (Curated mutations)ARHGEF37 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGEF37 (select a term)
intoGenARHGEF37
Cancer3DARHGEF37(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenARHGEF37
Genetic Testing Registry ARHGEF37
NextProtA1IGU5 [Medical]
TSGene389337
GENETestsARHGEF37
Target ValidationARHGEF37
Huge Navigator ARHGEF37 [HugePedia]
snp3D : Map Gene to Disease389337
BioCentury BCIQARHGEF37
ClinGenARHGEF37
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389337
Chemical/Pharm GKB GenePA165660135
Clinical trialARHGEF37
Miscellaneous
canSAR (ICR)ARHGEF37 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGEF37
EVEXARHGEF37
GoPubMedARHGEF37
iHOPARHGEF37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:42 CEST 2017

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