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ARHGEF38 (Rho guanine nucleotide exchange factor 38)

Identity

Alias_namesRho guanine nucleotide exchange factor (GEF) 38
Alias_symbol (synonym)FLJ20184
Other alias-
HGNC (Hugo) ARHGEF38
LocusID (NCBI) 54848
Atlas_Id 40598
Location 4q24  [Link to chromosome band 4q24]
Location_base_pair Starts at 105552620 and ends at 105680913 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKH (5p15.2) / ARHGEF38 (4q24)ARHGEF38 (4q24) / ANKH (5p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGEF38   25968
Cards
Entrez_Gene (NCBI)ARHGEF38  54848  Rho guanine nucleotide exchange factor 38
Aliases
GeneCards (Weizmann)ARHGEF38
Ensembl hg19 (Hinxton)ENSG00000236699 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000236699 [Gene_View]  chr4:105552620-105680913 [Contig_View]  ARHGEF38 [Vega]
ICGC DataPortalENSG00000236699
TCGA cBioPortalARHGEF38
AceView (NCBI)ARHGEF38
Genatlas (Paris)ARHGEF38
WikiGenes54848
SOURCE (Princeton)ARHGEF38
Genetics Home Reference (NIH)ARHGEF38
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF38  -     chr4:105552620-105680913 +  4q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF38  -     4q24   [Description]    (hg19-Feb_2009)
EnsemblARHGEF38 - 4q24 [CytoView hg19]  ARHGEF38 - 4q24 [CytoView hg38]
Mapping of homologs : NCBIARHGEF38 [Mapview hg19]  ARHGEF38 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000191 AK125951 BC105695 DT932593
RefSeq transcript (Entrez)NM_001242729 NM_017700
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGEF38
Cluster EST : UnigeneHs.744739 [ NCBI ]
CGAP (NCI)Hs.744739
Alternative Splicing GalleryENSG00000236699
Gene ExpressionARHGEF38 [ NCBI-GEO ]   ARHGEF38 [ EBI - ARRAY_EXPRESS ]   ARHGEF38 [ SEEK ]   ARHGEF38 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF38 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54848
GTEX Portal (Tissue expression)ARHGEF38
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NXL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NXL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NXL2
Splice isoforms : SwissVarQ9NXL2
PhosPhoSitePlusQ9NXL2
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    DH_2 (PS50010)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom    DH-domain    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)RhoGEF (PF00621)    SH3_2 (PF07653)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00621    pfam07653    pfam14604   
Domain families : Smart (EMBL)BAR (SM00721)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)ARHGEF38
DMDM Disease mutations54848
Blocks (Seattle)ARHGEF38
SuperfamilyQ9NXL2
Human Protein AtlasENSG00000236699
Peptide AtlasQ9NXL2
HPRD08613
IPIIPI00015005   IPI00868970   
Protein Interaction databases
DIP (DOE-UCLA)Q9NXL2
IntAct (EBI)Q9NXL2
FunCoupENSG00000236699
BioGRIDARHGEF38
STRING (EMBL)ARHGEF38
ZODIACARHGEF38
Ontologies - Pathways
QuickGOQ9NXL2
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  cytoplasm  small GTPase mediated signal transduction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  cytoplasm  small GTPase mediated signal transduction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
NDEx NetworkARHGEF38
Atlas of Cancer Signalling NetworkARHGEF38
Wikipedia pathwaysARHGEF38
Orthology - Evolution
OrthoDB54848
GeneTree (enSembl)ENSG00000236699
Phylogenetic Trees/Animal Genes : TreeFamARHGEF38
HOVERGENQ9NXL2
HOGENOMQ9NXL2
Homologs : HomoloGeneARHGEF38
Homology/Alignments : Family Browser (UCSC)ARHGEF38
Gene fusions - Rearrangements
Fusion : MitelmanANKH/ARHGEF38 [5p15.2/4q24]  [t(4;5)(q24;p15)]  
Fusion : MitelmanARHGEF38/ANKH [4q24/5p15.2]  [t(4;5)(q24;p15)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGEF38 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGEF38
dbVarARHGEF38
ClinVarARHGEF38
1000_GenomesARHGEF38 
Exome Variant ServerARHGEF38
ExAC (Exome Aggregation Consortium)ARHGEF38 (select the gene name)
Genetic variants : HAPMAP54848
Genomic Variants (DGV)ARHGEF38 [DGVbeta]
DECIPHERARHGEF38 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGEF38 
Mutations
ICGC Data PortalARHGEF38 
TCGA Data PortalARHGEF38 
Broad Tumor PortalARHGEF38
OASIS PortalARHGEF38 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGEF38  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARHGEF38
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARHGEF38
DgiDB (Drug Gene Interaction Database)ARHGEF38
DoCM (Curated mutations)ARHGEF38 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGEF38 (select a term)
intoGenARHGEF38
Cancer3DARHGEF38(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenARHGEF38
Genetic Testing Registry ARHGEF38
NextProtQ9NXL2 [Medical]
TSGene54848
GENETestsARHGEF38
Target ValidationARHGEF38
Huge Navigator ARHGEF38 [HugePedia]
snp3D : Map Gene to Disease54848
BioCentury BCIQARHGEF38
ClinGenARHGEF38
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54848
Chemical/Pharm GKB GenePA165663186
Clinical trialARHGEF38
Miscellaneous
canSAR (ICR)ARHGEF38 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGEF38
EVEXARHGEF38
GoPubMedARHGEF38
iHOPARHGEF38
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:24:22 CEST 2017

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