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ARHGEF38 (Rho guanine nucleotide exchange factor 38)

Identity

Alias (NCBI)-
HGNC (Hugo) ARHGEF38
HGNC Alias symbFLJ20184
HGNC Previous nameRho guanine nucleotide exchange factor (GEF) 38
LocusID (NCBI) 54848
Atlas_Id 40598
Location 4q24  [Link to chromosome band 4q24]
Location_base_pair Starts at 105552620 and ends at 105631680 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKH (5p15.2)::ARHGEF38 (4q24)ARHGEF38 (4q24)::ANKH (5p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ARHGEF38   25968
Cards
Entrez_Gene (NCBI)ARHGEF38    Rho guanine nucleotide exchange factor 38
Aliases
GeneCards (Weizmann)ARHGEF38
Ensembl hg19 (Hinxton)ENSG00000236699 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000236699 [Gene_View]  ENSG00000236699 [Sequence]  chr4:105552620-105631680 [Contig_View]  ARHGEF38 [Vega]
ICGC DataPortalENSG00000236699
TCGA cBioPortalARHGEF38
AceView (NCBI)ARHGEF38
Genatlas (Paris)ARHGEF38
SOURCE (Princeton)ARHGEF38
Genetics Home Reference (NIH)ARHGEF38
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF38  -     chr4:105552620-105631680 +  4q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF38  -     4q24   [Description]    (hg19-Feb_2009)
GoldenPathARHGEF38 - 4q24 [CytoView hg19]  ARHGEF38 - 4q24 [CytoView hg38]
ImmunoBaseENSG00000236699
Genome Data Viewer NCBIARHGEF38 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK000191 AK125951 BC105695 DT932593
RefSeq transcript (Entrez)NM_001242729 NM_017700
Consensus coding sequences : CCDS (NCBI)ARHGEF38
Gene ExpressionARHGEF38 [ NCBI-GEO ]   ARHGEF38 [ EBI - ARRAY_EXPRESS ]   ARHGEF38 [ SEEK ]   ARHGEF38 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF38 [ Firebrowse - Broad ]
GenevisibleExpression of ARHGEF38 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54848
GTEX Portal (Tissue expression)ARHGEF38
Human Protein AtlasENSG00000236699-ARHGEF38 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NXL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NXL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NXL2
PhosPhoSitePlusQ9NXL2
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    DH_2 (PS50010)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR_dom_sf    BAR_dom    DBL_dom_sf    DH-domain    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)RhoGEF (PF00621)    SH3_2 (PF07653)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00621    pfam07653    pfam14604   
Domain families : Smart (EMBL)BAR (SM00721)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)ARHGEF38
SuperfamilyQ9NXL2
AlphaFold pdb e-kbQ9NXL2   
Human Protein Atlas [tissue]ENSG00000236699-ARHGEF38 [tissue]
HPRD08613
Protein Interaction databases
DIP (DOE-UCLA)Q9NXL2
IntAct (EBI)Q9NXL2
BioGRIDARHGEF38
STRING (EMBL)ARHGEF38
ZODIACARHGEF38
Ontologies - Pathways
QuickGOQ9NXL2
Ontology : AmiGOguanyl-nucleotide exchange factor activity  cytoplasm  regulation of catalytic activity  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  cytoplasm  regulation of catalytic activity  
NDEx NetworkARHGEF38
Atlas of Cancer Signalling NetworkARHGEF38
Wikipedia pathwaysARHGEF38
Orthology - Evolution
OrthoDB54848
GeneTree (enSembl)ENSG00000236699
Phylogenetic Trees/Animal Genes : TreeFamARHGEF38
Homologs : HomoloGeneARHGEF38
Homology/Alignments : Family Browser (UCSC)ARHGEF38
Gene fusions - Rearrangements
Fusion : MitelmanANKH::ARHGEF38 [5p15.2/4q24]  
Fusion : MitelmanARHGEF38::ANKH [4q24/5p15.2]  
Fusion : QuiverARHGEF38
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGEF38 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGEF38
dbVarARHGEF38
ClinVarARHGEF38
MonarchARHGEF38
1000_GenomesARHGEF38 
Exome Variant ServerARHGEF38
GNOMAD BrowserENSG00000236699
Varsome BrowserARHGEF38
ACMGARHGEF38 variants
VarityQ9NXL2
Genomic Variants (DGV)ARHGEF38 [DGVbeta]
DECIPHERARHGEF38 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGEF38 
Mutations
ICGC Data PortalARHGEF38 
TCGA Data PortalARHGEF38 
Broad Tumor PortalARHGEF38
OASIS PortalARHGEF38 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARHGEF38  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DARHGEF38
Mutations and Diseases : HGMDARHGEF38
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaARHGEF38
DgiDB (Drug Gene Interaction Database)ARHGEF38
DoCM (Curated mutations)ARHGEF38
CIViC (Clinical Interpretations of Variants in Cancer)ARHGEF38
Cancer3DARHGEF38
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETARHGEF38
MedgenARHGEF38
Genetic Testing Registry ARHGEF38
NextProtQ9NXL2 [Medical]
GENETestsARHGEF38
Target ValidationARHGEF38
Huge Navigator ARHGEF38 [HugePedia]
ClinGenARHGEF38
Clinical trials, drugs, therapy
MyCancerGenomeARHGEF38
Protein Interactions : CTDARHGEF38
Pharm GKB GenePA165663186
PharosQ9NXL2
Clinical trialARHGEF38
Miscellaneous
canSAR (ICR)ARHGEF38
HarmonizomeARHGEF38
ARCHS4ARHGEF38
DataMed IndexARHGEF38
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXARHGEF38
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:23:10 CET 2022

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