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ARHGEF39 (Rho guanine nucleotide exchange factor 39)

Identity

Alias_namesC9orf100
chromosome 9 open reading frame 100
Rho guanine nucleotide exchange factor (GEF) 39
Alias_symbol (synonym)FLJ14642
Other alias
HGNC (Hugo) ARHGEF39
LocusID (NCBI) 84904
Atlas_Id 43176
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 35659344 and ends at 35665281 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NFX1 (9p13.3) / ARHGEF39 (9p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARHGEF39   25909
Cards
Entrez_Gene (NCBI)ARHGEF39  84904  Rho guanine nucleotide exchange factor 39
AliasesC9orf100
GeneCards (Weizmann)ARHGEF39
Ensembl hg19 (Hinxton)ENSG00000137135 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137135 [Gene_View]  chr9:35659344-35665281 [Contig_View]  ARHGEF39 [Vega]
ICGC DataPortalENSG00000137135
TCGA cBioPortalARHGEF39
AceView (NCBI)ARHGEF39
Genatlas (Paris)ARHGEF39
WikiGenes84904
SOURCE (Princeton)ARHGEF39
Genetics Home Reference (NIH)ARHGEF39
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF39  -     chr9:35659344-35665281 -  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF39  -     9p13.3   [Description]    (hg19-Feb_2009)
EnsemblARHGEF39 - 9p13.3 [CytoView hg19]  ARHGEF39 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBIARHGEF39 [Mapview hg19]  ARHGEF39 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001187 AK027548 AK225501 AK225529 AK303513
RefSeq transcript (Entrez)NM_032818
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGEF39
Cluster EST : UnigeneHs.534579 [ NCBI ]
CGAP (NCI)Hs.534579
Alternative Splicing GalleryENSG00000137135
Gene ExpressionARHGEF39 [ NCBI-GEO ]   ARHGEF39 [ EBI - ARRAY_EXPRESS ]   ARHGEF39 [ SEEK ]   ARHGEF39 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF39 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84904
GTEX Portal (Tissue expression)ARHGEF39
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N4T4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N4T4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N4T4
Splice isoforms : SwissVarQ8N4T4
PhosPhoSitePlusQ8N4T4
Domaine pattern : Prosite (Expaxy)DH_2 (PS50010)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)DH-domain    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)RhoGEF (PF00621)   
Domain families : Pfam (NCBI)pfam00621   
Domain families : Smart (EMBL)PH (SM00233)  RhoGEF (SM00325)  
Conserved Domain (NCBI)ARHGEF39
DMDM Disease mutations84904
Blocks (Seattle)ARHGEF39
SuperfamilyQ8N4T4
Human Protein AtlasENSG00000137135
Peptide AtlasQ8N4T4
HPRD12929
IPIIPI00181892   IPI00647746   IPI00844567   IPI00909628   
Protein Interaction databases
DIP (DOE-UCLA)Q8N4T4
IntAct (EBI)Q8N4T4
FunCoupENSG00000137135
BioGRIDARHGEF39
STRING (EMBL)ARHGEF39
ZODIACARHGEF39
Ontologies - Pathways
QuickGOQ8N4T4
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  protein binding  plasma membrane  positive regulation of cell migration  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  protein binding  plasma membrane  positive regulation of cell migration  regulation of Rho protein signal transduction  positive regulation of GTPase activity  
NDEx NetworkARHGEF39
Atlas of Cancer Signalling NetworkARHGEF39
Wikipedia pathwaysARHGEF39
Orthology - Evolution
OrthoDB84904
GeneTree (enSembl)ENSG00000137135
Phylogenetic Trees/Animal Genes : TreeFamARHGEF39
HOVERGENQ8N4T4
HOGENOMQ8N4T4
Homologs : HomoloGeneARHGEF39
Homology/Alignments : Family Browser (UCSC)ARHGEF39
Gene fusions - Rearrangements
Fusion : MitelmanNFX1/ARHGEF39 [9p13.3/9p13.3]  [t(9;9)(p13;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARHGEF39 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARHGEF39
dbVarARHGEF39
ClinVarARHGEF39
1000_GenomesARHGEF39 
Exome Variant ServerARHGEF39
ExAC (Exome Aggregation Consortium)ARHGEF39 (select the gene name)
Genetic variants : HAPMAP84904
Genomic Variants (DGV)ARHGEF39 [DGVbeta]
DECIPHERARHGEF39 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARHGEF39 
Mutations
ICGC Data PortalARHGEF39 
TCGA Data PortalARHGEF39 
Broad Tumor PortalARHGEF39
OASIS PortalARHGEF39 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDARHGEF39
BioMutasearch ARHGEF39
DgiDB (Drug Gene Interaction Database)ARHGEF39
DoCM (Curated mutations)ARHGEF39 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARHGEF39 (select a term)
intoGenARHGEF39
Cancer3DARHGEF39(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenARHGEF39
Genetic Testing Registry ARHGEF39
NextProtQ8N4T4 [Medical]
TSGene84904
GENETestsARHGEF39
Target ValidationARHGEF39
Huge Navigator ARHGEF39 [HugePedia]
snp3D : Map Gene to Disease84904
BioCentury BCIQARHGEF39
ClinGenARHGEF39
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84904
Chemical/Pharm GKB GenePA134939297
Clinical trialARHGEF39
Miscellaneous
canSAR (ICR)ARHGEF39 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARHGEF39
EVEXARHGEF39
GoPubMedARHGEF39
iHOPARHGEF39
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:24:23 CEST 2017

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