Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ARID2 (AT-rich interaction domain 2)

Identity

Alias_namesAT rich interactive domain 2 (ARID, RFX-like)
Alias_symbol (synonym)KIAA1557
DKFZp686G052
FLJ30619
BAF200
Other aliasCSS6
p200
HGNC (Hugo) ARID2
LocusID (NCBI) 196528
Atlas_Id 52470
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 45729706 and ends at 45908037 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID2 (12q12) / SCAF11 (12q12)ARID2 (12q12) / SUPT20H (13q13.3)ARID2 (12q12) / TMEM117 (12q12)
ARID2 (12q12) / TMPRSS2 (21q22.3)ARID2 (12q12) / YAF2 (12q12)ARID2 (12q12) / ZNF641 (12q13.11)
GNPTAB (12q23.2) / ARID2 (12q12)ARID2 12q12 / SCAF11 12q12ARID2 12q12 / TMPRSS2 21q22.3
ARID2 12q12 / ZNF641 12q13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(12;12)(q12;q13) ARID2/ZNF641
t(12;21)(q12;q22) ARID2/TMPRSS2

External links

Nomenclature
HGNC (Hugo)ARID2   18037
Cards
Entrez_Gene (NCBI)ARID2  196528  AT-rich interaction domain 2
AliasesBAF200; CSS6; p200
GeneCards (Weizmann)ARID2
Ensembl hg19 (Hinxton)ENSG00000189079 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189079 [Gene_View]  ENSG00000189079 [Sequence]  chr12:45729706-45908037 [Contig_View]  ARID2 [Vega]
ICGC DataPortalENSG00000189079
TCGA cBioPortalARID2
AceView (NCBI)ARID2
Genatlas (Paris)ARID2
WikiGenes196528
SOURCE (Princeton)ARID2
Genetics Home Reference (NIH)ARID2
Genomic and cartography
GoldenPath hg38 (UCSC)ARID2  -     chr12:45729706-45908037 +  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARID2  -     12q12   [Description]    (hg19-Feb_2009)
GoldenPathARID2 - 12q12 [CytoView hg19]  ARID2 - 12q12 [CytoView hg38]
Genome Data Viewer NCBIARID2 [Mapview hg19]  
OMIM609539   617808   
Gene and transcription
Genbank (Entrez)AB046777 AK027617 AK027718 AK055181 AK075385
RefSeq transcript (Entrez)NM_001347839 NM_152641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARID2
Alternative Splicing GalleryENSG00000189079
Gene ExpressionARID2 [ NCBI-GEO ]   ARID2 [ EBI - ARRAY_EXPRESS ]   ARID2 [ SEEK ]   ARID2 [ MEM ]
Gene Expression Viewer (FireBrowse)ARID2 [ Firebrowse - Broad ]
GenevisibleExpression of ARID2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)196528
GTEX Portal (Tissue expression)ARID2
Human Protein AtlasENSG00000189079-ARID2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68CP9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68CP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68CP9
Splice isoforms : SwissVarQ68CP9
PhosPhoSitePlusQ68CP9
Domaine pattern : Prosite (Expaxy)ARID (PS51011)    RFX_DBD (PS51526)    ZINC_FINGER_C2H2_1 (PS00028)   
Domains : Interpro (EBI)ARID_dom    ARID_dom_sf    ARM-type_fold    DNA-bd_RFX    WH-like_DNA-bd_sf    WH_DNA-bd_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)ARID (PF01388)    RFX_DNA_binding (PF02257)   
Domain families : Pfam (NCBI)pfam01388    pfam02257   
Domain families : Smart (EMBL)BRIGHT (SM00501)  
Conserved Domain (NCBI)ARID2
DMDM Disease mutations196528
SuperfamilyQ68CP9
Human Protein Atlas [tissue]ENSG00000189079-ARID2 [tissue]
Peptide AtlasQ68CP9
HPRD16505
IPIIPI00470537   IPI00444237   IPI00647133   IPI00884387   IPI01017948   IPI01024924   
Protein Interaction databases
DIP (DOE-UCLA)Q68CP9
IntAct (EBI)Q68CP9
FunCoupENSG00000189079
BioGRIDARID2
STRING (EMBL)ARID2
ZODIACARID2
Ontologies - Pathways
QuickGOQ68CP9
Ontology : AmiGOheart morphogenesis  DNA binding  protein binding  nucleoplasm  plasma membrane  nucleosome disassembly  regulation of transcription, DNA-templated  negative regulation of cell proliferation  negative regulation of cell migration  homeostatic process  metal ion binding  embryonic organ development  cardiac muscle cell proliferation  coronary artery morphogenesis  positive regulation of double-strand break repair via homologous recombination  
Ontology : EGO-EBIheart morphogenesis  DNA binding  protein binding  nucleoplasm  plasma membrane  nucleosome disassembly  regulation of transcription, DNA-templated  negative regulation of cell proliferation  negative regulation of cell migration  homeostatic process  metal ion binding  embryonic organ development  cardiac muscle cell proliferation  coronary artery morphogenesis  positive regulation of double-strand break repair via homologous recombination  
NDEx NetworkARID2
Atlas of Cancer Signalling NetworkARID2
Wikipedia pathwaysARID2
Orthology - Evolution
OrthoDB196528
GeneTree (enSembl)ENSG00000189079
Phylogenetic Trees/Animal Genes : TreeFamARID2
HOGENOMQ68CP9
Homologs : HomoloGeneARID2
Homology/Alignments : Family Browser (UCSC)ARID2
Gene fusions - Rearrangements
Fusion : MitelmanARID2/TMPRSS2 [12q12/21q22.3]  
Fusion : MitelmanARID2/ZNF641 [12q12/12q13.11]  
Fusion PortalARID2 12q12 SCAF11 12q12 SKCM
Fusion PortalARID2 12q12 TMPRSS2 21q22.3 BRCA
Fusion PortalARID2 12q12 ZNF641 12q13.11 BRCA
Fusion : QuiverARID2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARID2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARID2
dbVarARID2
ClinVarARID2
1000_GenomesARID2 
Exome Variant ServerARID2
GNOMAD BrowserENSG00000189079
Varsome BrowserARID2
Genetic variants : HAPMAP196528
Genomic Variants (DGV)ARID2 [DGVbeta]
DECIPHERARID2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARID2 
Mutations
ICGC Data PortalARID2 
TCGA Data PortalARID2 
Broad Tumor PortalARID2
OASIS PortalARID2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARID2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DARID2
Mutations and Diseases : HGMDARID2
intOGen PortalARID2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect ARID2
DgiDB (Drug Gene Interaction Database)ARID2
DoCM (Curated mutations)ARID2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARID2 (select a term)
intoGenARID2
Cancer3DARID2 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609539    617808   
Orphanet
DisGeNETARID2
MedgenARID2
Genetic Testing Registry ARID2
NextProtQ68CP9 [Medical]
TSGene196528
GENETestsARID2
Open Targets GeneticsENSG00000189079  [validation]
snp3D : Map Gene to Disease196528
BioCentury BCIQARID2
ClinGenARID2
Clinical trials, drugs, therapy
Protein Interactions : CTD196528
Pharm GKB GenePA134916396
Clinical trialARID2
Miscellaneous
canSAR (ICR)ARID2 (select the gene name)
HarmonizomeARID2
DataMed IndexARID2
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARID2
EVEXARID2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Jul 11 19:39:32 CEST 2020
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