ARID3B (AT-rich interaction domain 3B)

2010-01-01  

Identity

HGNC
ARID3B
LOCATION
15q24.1
LOCUSID
10620
ALIAS
BDP,DRIL2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10620
MIM: 612457
HGNC: 14350
Ensembl: ENSG00000179361

Variants:

dbSNP: 10620
ClinVar: 10620
TCGA: ENSG00000179361
COSMIC: ARID3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179361ENST00000346246Q8IVW6
ENSG00000179361ENST00000566147H3BQ92
ENSG00000179361ENST00000622429Q8IVW6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
198819562009The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells.58
223074042012miR-125b targets ARID3B in breast cancer cells.19
227511322013Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn.14
253275632014ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene signature.11
228600692012ARID3B induces tumor necrosis factor alpha mediated apoptosis while a novel ARID3B splice form does not induce cell death.8
275120772016ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.7
247042762014Differential expression of ARID3B in normal adult tissue and carcinomas.4
270259272016Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.4
265198812015Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis.3

Citation

Dessen P

ARID3B (AT-rich interaction domain 3B)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51281/arid3b