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ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)

Identity

Alias_namesDrosophila
homolog of
Alias_symbol (synonym)HARI
HHARI
UBCH7BP
ARI
Other alias
HGNC (Hugo) ARIH1
LocusID (NCBI) 25820
Atlas_Id 46930
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 72474326 and ends at 72586555 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARIH1 (15q24.1) / ARIH1 (15q24.1)ARIH1 (15q24.1) / EPB41L1 (20q11.23)ARIH1 (15q24.1) / OLFM1 (9q34.3)
PIK3R2 (19p13.11) / ARIH1 (15q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARIH1   689
Cards
Entrez_Gene (NCBI)ARIH1  25820  ariadne RBR E3 ubiquitin protein ligase 1
AliasesARI; HARI; HHARI; UBCH7BP
GeneCards (Weizmann)ARIH1
Ensembl hg19 (Hinxton)ENSG00000166233 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166233 [Gene_View]  chr15:72474326-72586555 [Contig_View]  ARIH1 [Vega]
ICGC DataPortalENSG00000166233
TCGA cBioPortalARIH1
AceView (NCBI)ARIH1
Genatlas (Paris)ARIH1
WikiGenes25820
SOURCE (Princeton)ARIH1
Genetics Home Reference (NIH)ARIH1
Genomic and cartography
GoldenPath hg38 (UCSC)ARIH1  -     chr15:72474326-72586555 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARIH1  -     15q24.1   [Description]    (hg19-Feb_2009)
EnsemblARIH1 - 15q24.1 [CytoView hg19]  ARIH1 - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBIARIH1 [Mapview hg19]  ARIH1 [Mapview hg38]
OMIM605624   
Gene and transcription
Genbank (Entrez)AB014774 AB209432 AF072832 AJ009771 AJ130976
RefSeq transcript (Entrez)NM_005744
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARIH1
Cluster EST : UnigeneHs.268787 [ NCBI ]
CGAP (NCI)Hs.268787
Alternative Splicing GalleryENSG00000166233
Gene ExpressionARIH1 [ NCBI-GEO ]   ARIH1 [ EBI - ARRAY_EXPRESS ]   ARIH1 [ SEEK ]   ARIH1 [ MEM ]
Gene Expression Viewer (FireBrowse)ARIH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25820
GTEX Portal (Tissue expression)ARIH1
Human Protein AtlasENSG00000166233-ARIH1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4X5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4X5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4X5
Splice isoforms : SwissVarQ9Y4X5
PhosPhoSitePlusQ9Y4X5
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)E3_UB_ligase_RBR    IBR_dom    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)IBR (PF01485)   
Domain families : Pfam (NCBI)pfam01485   
Domain families : Smart (EMBL)IBR (SM00647)  RING (SM00184)  
Conserved Domain (NCBI)ARIH1
DMDM Disease mutations25820
Blocks (Seattle)ARIH1
PDB (SRS)1WD2    2M9Y    4KBL    4KC9   
PDB (PDBSum)1WD2    2M9Y    4KBL    4KC9   
PDB (IMB)1WD2    2M9Y    4KBL    4KC9   
PDB (RSDB)1WD2    2M9Y    4KBL    4KC9   
Structural Biology KnowledgeBase1WD2    2M9Y    4KBL    4KC9   
SCOP (Structural Classification of Proteins)1WD2    2M9Y    4KBL    4KC9   
CATH (Classification of proteins structures)1WD2    2M9Y    4KBL    4KC9   
SuperfamilyQ9Y4X5
Human Protein Atlas [tissue]ENSG00000166233-ARIH1 [tissue]
Peptide AtlasQ9Y4X5
HPRD05730
IPIIPI00294943   IPI00641694   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4X5
IntAct (EBI)Q9Y4X5
FunCoupENSG00000166233
BioGRIDARIH1
STRING (EMBL)ARIH1
ZODIACARIH1
Ontologies - Pathways
QuickGOQ9Y4X5
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  zinc ion binding  Cajal body  protein ubiquitination  nuclear body  SCF ubiquitin ligase complex  ubiquitin-like protein transferase activity  Cul2-RING ubiquitin ligase complex  Cul2-RING ubiquitin ligase complex  Cul3-RING ubiquitin ligase complex  Cul4A-RING E3 ubiquitin ligase complex  ubiquitin conjugating enzyme binding  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  Lewy body  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  zinc ion binding  Cajal body  protein ubiquitination  nuclear body  SCF ubiquitin ligase complex  ubiquitin-like protein transferase activity  Cul2-RING ubiquitin ligase complex  Cul2-RING ubiquitin ligase complex  Cul3-RING ubiquitin ligase complex  Cul4A-RING E3 ubiquitin ligase complex  ubiquitin conjugating enzyme binding  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  Lewy body  
NDEx NetworkARIH1
Atlas of Cancer Signalling NetworkARIH1
Wikipedia pathwaysARIH1
Orthology - Evolution
OrthoDB25820
GeneTree (enSembl)ENSG00000166233
Phylogenetic Trees/Animal Genes : TreeFamARIH1
HOVERGENQ9Y4X5
HOGENOMQ9Y4X5
Homologs : HomoloGeneARIH1
Homology/Alignments : Family Browser (UCSC)ARIH1
Gene fusions - Rearrangements
Tumor Fusion PortalARIH1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARIH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARIH1
dbVarARIH1
ClinVarARIH1
1000_GenomesARIH1 
Exome Variant ServerARIH1
ExAC (Exome Aggregation Consortium)ENSG00000166233
GNOMAD BrowserENSG00000166233
Genetic variants : HAPMAP25820
Genomic Variants (DGV)ARIH1 [DGVbeta]
DECIPHERARIH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARIH1 
Mutations
ICGC Data PortalARIH1 
TCGA Data PortalARIH1 
Broad Tumor PortalARIH1
OASIS PortalARIH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARIH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARIH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARIH1
DgiDB (Drug Gene Interaction Database)ARIH1
DoCM (Curated mutations)ARIH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARIH1 (select a term)
intoGenARIH1
Cancer3DARIH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605624   
Orphanet
DisGeNETARIH1
MedgenARIH1
Genetic Testing Registry ARIH1
NextProtQ9Y4X5 [Medical]
TSGene25820
GENETestsARIH1
Target ValidationARIH1
Huge Navigator ARIH1 [HugePedia]
snp3D : Map Gene to Disease25820
BioCentury BCIQARIH1
ClinGenARIH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25820
Chemical/Pharm GKB GenePA24982
Clinical trialARIH1
Miscellaneous
canSAR (ICR)ARIH1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARIH1
EVEXARIH1
GoPubMedARIH1
iHOPARIH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:44 CET 2017

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