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ARL3 (ADP ribosylation factor like GTPase 3)

Identity

Alias_namesADP-ribosylation factor-like 3
Alias_symbol (synonym)ARFL3
Other alias
HGNC (Hugo) ARL3
LocusID (NCBI) 403
Atlas_Id 706
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102673727 and ends at 102714433 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARL3 (10q24.32) / ACO1 (9p21.1)ARL3 (10q24.32) / ACTR1A (10q24.32)MTF2 (1p22.1) / ARL3 (10q24.32)
WBP1L (10q24.32) / ARL3 (10q24.32)C10orf26 ARL3 10q24.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARL3   694
Cards
Entrez_Gene (NCBI)ARL3  403  ADP ribosylation factor like GTPase 3
AliasesARFL3
GeneCards (Weizmann)ARL3
Ensembl hg19 (Hinxton)ENSG00000138175 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138175 [Gene_View]  chr10:102673727-102714433 [Contig_View]  ARL3 [Vega]
ICGC DataPortalENSG00000138175
TCGA cBioPortalARL3
AceView (NCBI)ARL3
Genatlas (Paris)ARL3
WikiGenes403
SOURCE (Princeton)ARL3
Genetics Home Reference (NIH)ARL3
Genomic and cartography
GoldenPath hg38 (UCSC)ARL3  -     chr10:102673727-102714433 -  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARL3  -     10q24.32   [Description]    (hg19-Feb_2009)
EnsemblARL3 - 10q24.32 [CytoView hg19]  ARL3 - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBIARL3 [Mapview hg19]  ARL3 [Mapview hg38]
OMIM604695   
Gene and transcription
Genbank (Entrez)AA325516 AF038193 AF493889 AK312525 AW269939
RefSeq transcript (Entrez)NM_004311
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARL3
Cluster EST : UnigeneHs.182215 [ NCBI ]
CGAP (NCI)Hs.182215
Alternative Splicing GalleryENSG00000138175
Gene ExpressionARL3 [ NCBI-GEO ]   ARL3 [ EBI - ARRAY_EXPRESS ]   ARL3 [ SEEK ]   ARL3 [ MEM ]
Gene Expression Viewer (FireBrowse)ARL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)403
GTEX Portal (Tissue expression)ARL3
Human Protein AtlasENSG00000138175-ARL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36405   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36405  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36405
Splice isoforms : SwissVarP36405
PhosPhoSitePlusP36405
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)ARL3
DMDM Disease mutations403
Blocks (Seattle)ARL3
SuperfamilyP36405
Human Protein Atlas [tissue]ENSG00000138175-ARL3 [tissue]
Peptide AtlasP36405
HPRD05260
IPIIPI00003327   
Protein Interaction databases
DIP (DOE-UCLA)P36405
IntAct (EBI)P36405
FunCoupENSG00000138175
BioGRIDARL3
STRING (EMBL)ARL3
ZODIACARL3
Ontologies - Pathways
QuickGOP36405
Ontology : AmiGOGolgi membrane  cytokinesis  kidney development  GTPase activity  protein binding  GTP binding  nucleus  Golgi apparatus  centrosome  spindle microtubule  cytoplasmic microtubule  cilium  cilium  cilium  post-Golgi vesicle-mediated transport  smoothened signaling pathway  small GTPase mediated signal transduction  microtubule binding  GDP binding  midbody  photoreceptor connecting cilium  intraciliary transport  photoreceptor cell development  metal ion binding  cilium assembly  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  cytokinesis  kidney development  GTPase activity  protein binding  GTP binding  nucleus  Golgi apparatus  centrosome  spindle microtubule  cytoplasmic microtubule  cilium  cilium  cilium  post-Golgi vesicle-mediated transport  smoothened signaling pathway  small GTPase mediated signal transduction  microtubule binding  GDP binding  midbody  photoreceptor connecting cilium  intraciliary transport  photoreceptor cell development  metal ion binding  cilium assembly  extracellular exosome  
NDEx NetworkARL3
Atlas of Cancer Signalling NetworkARL3
Wikipedia pathwaysARL3
Orthology - Evolution
OrthoDB403
GeneTree (enSembl)ENSG00000138175
Phylogenetic Trees/Animal Genes : TreeFamARL3
HOVERGENP36405
HOGENOMP36405
Homologs : HomoloGeneARL3
Homology/Alignments : Family Browser (UCSC)ARL3
Gene fusions - Rearrangements
Fusion : MitelmanARL3/ACO1 [10q24.32/9p21.1]  
Fusion : MitelmanMTF2/ARL3 [1p22.1/10q24.32]  [t(1;10)(p22;q24)]  
Fusion : MitelmanWBP1L/ARL3 [10q24.32/10q24.32]  [t(10;10)(q24;q24)]  
Fusion: TCGA_MDACCC10orf26 ARL3 10q24.32 BRCA
Tumor Fusion PortalARL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARL3
dbVarARL3
ClinVarARL3
1000_GenomesARL3 
Exome Variant ServerARL3
ExAC (Exome Aggregation Consortium)ENSG00000138175
GNOMAD BrowserENSG00000138175
Genetic variants : HAPMAP403
Genomic Variants (DGV)ARL3 [DGVbeta]
DECIPHERARL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARL3 
Mutations
ICGC Data PortalARL3 
TCGA Data PortalARL3 
Broad Tumor PortalARL3
OASIS PortalARL3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDARL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARL3
DgiDB (Drug Gene Interaction Database)ARL3
DoCM (Curated mutations)ARL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARL3 (select a term)
intoGenARL3
Cancer3DARL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604695   
Orphanet
DisGeNETARL3
MedgenARL3
Genetic Testing Registry ARL3
NextProtP36405 [Medical]
TSGene403
GENETestsARL3
Target ValidationARL3
Huge Navigator ARL3 [HugePedia]
snp3D : Map Gene to Disease403
BioCentury BCIQARL3
ClinGenARL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD403
Chemical/Pharm GKB GenePA24987
Clinical trialARL3
Miscellaneous
canSAR (ICR)ARL3 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARL3
EVEXARL3
GoPubMedARL3
iHOPARL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:03:46 CET 2017

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