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ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1)

Identity

Alias_namesARL6IP
ADP-ribosylation factor-like 6 interacting protein
ADP-ribosylation factor-like 6 interacting protein 1
Alias_symbol (synonym)AIP1
ARMER
KIAA0069
SPG61
Other alias
HGNC (Hugo) ARL6IP1
LocusID (NCBI) 23204
Atlas_Id 51569
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 18791667 and ends at 18801370 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARL6IP1 (16p12.3) / APLP2 (11q24.3)ARL6IP1 (16p12.3) / RPS15A (16p12.3)SMG1 (16p12.3) / ARL6IP1 (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARL6IP1   697
Cards
Entrez_Gene (NCBI)ARL6IP1  23204  ADP ribosylation factor like GTPase 6 interacting protein 1
AliasesAIP1; ARL6IP; ARMER; SPG61
GeneCards (Weizmann)ARL6IP1
Ensembl hg19 (Hinxton)ENSG00000170540 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170540 [Gene_View]  chr16:18791667-18801370 [Contig_View]  ARL6IP1 [Vega]
ICGC DataPortalENSG00000170540
TCGA cBioPortalARL6IP1
AceView (NCBI)ARL6IP1
Genatlas (Paris)ARL6IP1
WikiGenes23204
SOURCE (Princeton)ARL6IP1
Genetics Home Reference (NIH)ARL6IP1
Genomic and cartography
GoldenPath hg38 (UCSC)ARL6IP1  -     chr16:18791667-18801370 -  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARL6IP1  -     16p12.3   [Description]    (hg19-Feb_2009)
EnsemblARL6IP1 - 16p12.3 [CytoView hg19]  ARL6IP1 - 16p12.3 [CytoView hg38]
Mapping of homologs : NCBIARL6IP1 [Mapview hg19]  ARL6IP1 [Mapview hg38]
OMIM607669   615685   
Gene and transcription
Genbank (Entrez)AI354532 AK291137 AK300825 AK300869 AK301636
RefSeq transcript (Entrez)NM_001313858 NM_015161
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARL6IP1
Cluster EST : UnigeneHs.634882 [ NCBI ]
CGAP (NCI)Hs.634882
Alternative Splicing GalleryENSG00000170540
Gene ExpressionARL6IP1 [ NCBI-GEO ]   ARL6IP1 [ EBI - ARRAY_EXPRESS ]   ARL6IP1 [ SEEK ]   ARL6IP1 [ MEM ]
Gene Expression Viewer (FireBrowse)ARL6IP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23204
GTEX Portal (Tissue expression)ARL6IP1
Human Protein AtlasENSG00000170540-ARL6IP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15041   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15041  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15041
Splice isoforms : SwissVarQ15041
PhosPhoSitePlusQ15041
Domains : Interpro (EBI)ARL6IP   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ARL6IP1
DMDM Disease mutations23204
Blocks (Seattle)ARL6IP1
SuperfamilyQ15041
Human Protein Atlas [tissue]ENSG00000170540-ARL6IP1 [tissue]
Peptide AtlasQ15041
HPRD09641
IPIIPI00014232   IPI01015633   IPI01010487   
Protein Interaction databases
DIP (DOE-UCLA)Q15041
IntAct (EBI)Q15041
FunCoupENSG00000170540
BioGRIDARL6IP1
STRING (EMBL)ARL6IP1
ZODIACARL6IP1
Ontologies - Pathways
QuickGOQ15041
Ontology : AmiGOpositive regulation of L-glutamate transport  protein binding  Sec61 translocon complex  endoplasmic reticulum membrane  cytosol  cotranslational protein targeting to membrane  apoptotic process  membrane  integral component of endoplasmic reticulum membrane  identical protein binding  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  endoplasmic reticulum tubular network formation  endoplasmic reticulum tubular network membrane organization  
Ontology : EGO-EBIpositive regulation of L-glutamate transport  protein binding  Sec61 translocon complex  endoplasmic reticulum membrane  cytosol  cotranslational protein targeting to membrane  apoptotic process  membrane  integral component of endoplasmic reticulum membrane  identical protein binding  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  endoplasmic reticulum tubular network formation  endoplasmic reticulum tubular network membrane organization  
NDEx NetworkARL6IP1
Atlas of Cancer Signalling NetworkARL6IP1
Wikipedia pathwaysARL6IP1
Orthology - Evolution
OrthoDB23204
GeneTree (enSembl)ENSG00000170540
Phylogenetic Trees/Animal Genes : TreeFamARL6IP1
HOVERGENQ15041
HOGENOMQ15041
Homologs : HomoloGeneARL6IP1
Homology/Alignments : Family Browser (UCSC)ARL6IP1
Gene fusions - Rearrangements
Fusion : MitelmanARL6IP1/RPS15A [16p12.3/16p12.3]  
Tumor Fusion PortalARL6IP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARL6IP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARL6IP1
dbVarARL6IP1
ClinVarARL6IP1
1000_GenomesARL6IP1 
Exome Variant ServerARL6IP1
ExAC (Exome Aggregation Consortium)ENSG00000170540
GNOMAD BrowserENSG00000170540
Genetic variants : HAPMAP23204
Genomic Variants (DGV)ARL6IP1 [DGVbeta]
DECIPHERARL6IP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARL6IP1 
Mutations
ICGC Data PortalARL6IP1 
TCGA Data PortalARL6IP1 
Broad Tumor PortalARL6IP1
OASIS PortalARL6IP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARL6IP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARL6IP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARL6IP1
DgiDB (Drug Gene Interaction Database)ARL6IP1
DoCM (Curated mutations)ARL6IP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARL6IP1 (select a term)
intoGenARL6IP1
Cancer3DARL6IP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607669    615685   
Orphanet22828   
DisGeNETARL6IP1
MedgenARL6IP1
Genetic Testing Registry ARL6IP1
NextProtQ15041 [Medical]
TSGene23204
GENETestsARL6IP1
Target ValidationARL6IP1
Huge Navigator ARL6IP1 [HugePedia]
snp3D : Map Gene to Disease23204
BioCentury BCIQARL6IP1
ClinGenARL6IP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23204
Chemical/Pharm GKB GenePA162376894
Clinical trialARL6IP1
Miscellaneous
canSAR (ICR)ARL6IP1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARL6IP1
EVEXARL6IP1
GoPubMedARL6IP1
iHOPARL6IP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:47 CET 2017

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