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ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5)

Identity

Other namesDERP11
GTRAP3-18
HSPC127
JWA
PRAF3
Yip6b
addicsin
hp22
jmx
HGNC (Hugo) ARL6IP5
LocusID (NCBI) 10550
Atlas_Id 47637
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 69134090 and ends at 69155239 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARL6IP5 (3p14.1) / EBF3 (10q26.3)NBAS (2p24.3) / ARL6IP5 (3p14.1)RPL13A (19q13.33) / ARL6IP5 (3p14.1)
TPH1 (11p15.1) / ARL6IP5 (3p14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARL6IP5   16937
Cards
Entrez_Gene (NCBI)ARL6IP5  10550  ADP ribosylation factor like GTPase 6 interacting protein 5
AliasesDERP11; GTRAP3-18; HSPC127; JWA; 
PRAF3; Yip6b; addicsin; hp22; jmx
GeneCards (Weizmann)ARL6IP5
Ensembl hg19 (Hinxton)ENSG00000144746 [Gene_View]  chr3:69134090-69155239 [Contig_View]  ARL6IP5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000144746 [Gene_View]  chr3:69134090-69155239 [Contig_View]  ARL6IP5 [Vega]
ICGC DataPortalENSG00000144746
TCGA cBioPortalARL6IP5
AceView (NCBI)ARL6IP5
Genatlas (Paris)ARL6IP5
WikiGenes10550
SOURCE (Princeton)ARL6IP5
Genomic and cartography
GoldenPath hg19 (UCSC)ARL6IP5  -     chr3:69134090-69155239 +  3p14.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARL6IP5  -     3p14.1   [Description]    (hg38-Dec_2013)
EnsemblARL6IP5 - 3p14.1 [CytoView hg19]  ARL6IP5 - 3p14.1 [CytoView hg38]
Mapping of homologs : NCBIARL6IP5 [Mapview hg19]  ARL6IP5 [Mapview hg38]
OMIM605709   
Gene and transcription
Genbank (Entrez)AB014765 AB052638 AB097051 AF070523 AF115965
RefSeq transcript (Entrez)NM_006407
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929310
Consensus coding sequences : CCDS (NCBI)ARL6IP5
Cluster EST : UnigeneHs.745255 [ NCBI ]
CGAP (NCI)Hs.745255
Alternative Splicing GalleryENSG00000144746
Gene ExpressionARL6IP5 [ NCBI-GEO ]   ARL6IP5 [ EBI - ARRAY_EXPRESS ]   ARL6IP5 [ SEEK ]   ARL6IP5 [ MEM ]
Gene Expression Viewer (FireBrowse)ARL6IP5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10550
GTEX Portal (Tissue expression)ARL6IP5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75915 (Uniprot)
NextProtO75915  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75915
Splice isoforms : SwissVarO75915 (Swissvar)
PhosPhoSitePlusO75915
Domains : Interpro (EBI)Prenylated_rab_accept_PRA1   
Domain families : Pfam (Sanger)PRA1 (PF03208)   
Domain families : Pfam (NCBI)pfam03208   
DMDM Disease mutations10550
Blocks (Seattle)ARL6IP5
SuperfamilyO75915
Human Protein AtlasENSG00000144746
Peptide AtlasO75915
HPRD09303
IPIIPI00007426   IPI00908696   IPI00946721   IPI00945943   
Protein Interaction databases
DIP (DOE-UCLA)O75915
IntAct (EBI)O75915
FunCoupENSG00000144746
BioGRIDARL6IP5
STRING (EMBL)ARL6IP5
ZODIACARL6IP5
Ontologies - Pathways
QuickGOO75915
Ontology : AmiGOnegative regulation of L-glutamate transport  molecular_function  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  cytoskeleton  plasma membrane  intrinsic apoptotic signaling pathway in response to oxidative stress  negative regulation of mitochondrial membrane potential  L-glutamate transport  membrane  integral component of membrane  positive regulation of stress-activated MAPK cascade  positive regulation of apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  extracellular exosome  
Ontology : EGO-EBInegative regulation of L-glutamate transport  molecular_function  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  cytoskeleton  plasma membrane  intrinsic apoptotic signaling pathway in response to oxidative stress  negative regulation of mitochondrial membrane potential  L-glutamate transport  membrane  integral component of membrane  positive regulation of stress-activated MAPK cascade  positive regulation of apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  extracellular exosome  
NDEx NetworkARL6IP5
Atlas of Cancer Signalling NetworkARL6IP5
Wikipedia pathwaysARL6IP5
Orthology - Evolution
OrthoDB10550
GeneTree (enSembl)ENSG00000144746
Phylogenetic Trees/Animal Genes : TreeFamARL6IP5
Homologs : HomoloGeneARL6IP5
Homology/Alignments : Family Browser (UCSC)ARL6IP5
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerARL6IP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARL6IP5
dbVarARL6IP5
ClinVarARL6IP5
1000_GenomesARL6IP5 
Exome Variant ServerARL6IP5
ExAC (Exome Aggregation Consortium)ARL6IP5 (select the gene name)
Genetic variants : HAPMAP10550
Genomic Variants (DGV)ARL6IP5 [DGVbeta]
Mutations
ICGC Data PortalARL6IP5 
TCGA Data PortalARL6IP5 
Broad Tumor PortalARL6IP5
OASIS PortalARL6IP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARL6IP5 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARL6IP5
DgiDB (Drug Gene Interaction Database)ARL6IP5
DoCM (Curated mutations)ARL6IP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARL6IP5 (select a term)
intoGenARL6IP5
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:69134090-69155239  ENSG00000144746
CONAN: Copy Number AnalysisARL6IP5 
Mutations and Diseases : HGMDARL6IP5
OMIM605709   
MedgenARL6IP5
Genetic Testing Registry ARL6IP5
NextProtO75915 [Medical]
TSGene10550
GENETestsARL6IP5
Huge Navigator ARL6IP5 [HugePedia]
snp3D : Map Gene to Disease10550
BioCentury BCIQARL6IP5
ClinGenARL6IP5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10550
Chemical/Pharm GKB GenePA134898937
Clinical trialARL6IP5
Miscellaneous
canSAR (ICR)ARL6IP5 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARL6IP5
EVEXARL6IP5
GoPubMedARL6IP5
iHOPARL6IP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:37:25 CEST 2016

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