Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ARL8A (ADP-ribosylation factor-like 8A)

Identity

Alias_namesARL10B
ADP-ribosylation factor-like 10B
ADP-ribosylation factor-like 8A
Alias_symbol (synonym)FLJ45195
Gie2
Other aliasGIE2
HGNC (Hugo) ARL8A
LocusID (NCBI) 127829
Atlas_Id 60504
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 202102532 and ends at 202113871 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARL8A (1q32.1) / ARL8A (1q32.1)MIDN (19p13.3) / ARL8A (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARL8A   25192
Cards
Entrez_Gene (NCBI)ARL8A  127829  ADP-ribosylation factor-like 8A
AliasesARL10B; GIE2
GeneCards (Weizmann)ARL8A
Ensembl hg19 (Hinxton)ENSG00000143862 [Gene_View]  chr1:202102532-202113871 [Contig_View]  ARL8A [Vega]
Ensembl hg38 (Hinxton)ENSG00000143862 [Gene_View]  chr1:202102532-202113871 [Contig_View]  ARL8A [Vega]
ICGC DataPortalENSG00000143862
TCGA cBioPortalARL8A
AceView (NCBI)ARL8A
Genatlas (Paris)ARL8A
WikiGenes127829
SOURCE (Princeton)ARL8A
Genetics Home Reference (NIH)ARL8A
Genomic and cartography
GoldenPath hg19 (UCSC)ARL8A  -     chr1:202102532-202113871 -  1q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARL8A  -     1q32.1   [Description]    (hg38-Dec_2013)
EnsemblARL8A - 1q32.1 [CytoView hg19]  ARL8A - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIARL8A [Mapview hg19]  ARL8A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB118752 AK127138 AK313122 AW090198 BC015408
RefSeq transcript (Entrez)NM_001256129 NM_138795
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)ARL8A
Cluster EST : UnigeneHs.604697 [ NCBI ]
CGAP (NCI)Hs.604697
Alternative Splicing GalleryENSG00000143862
Gene ExpressionARL8A [ NCBI-GEO ]   ARL8A [ EBI - ARRAY_EXPRESS ]   ARL8A [ SEEK ]   ARL8A [ MEM ]
Gene Expression Viewer (FireBrowse)ARL8A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)127829
GTEX Portal (Tissue expression)ARL8A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96BM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96BM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96BM9
Splice isoforms : SwissVarQ96BM9
PhosPhoSitePlusQ96BM9
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Domain families : Smart (EMBL)ARF (SM00177)  
Conserved Domain (NCBI)ARL8A
DMDM Disease mutations127829
Blocks (Seattle)ARL8A
PDB (SRS)1ZD9    2H18    4ILE   
PDB (PDBSum)1ZD9    2H18    4ILE   
PDB (IMB)1ZD9    2H18    4ILE   
PDB (RSDB)1ZD9    2H18    4ILE   
Structural Biology KnowledgeBase1ZD9    2H18    4ILE   
SCOP (Structural Classification of Proteins)1ZD9    2H18    4ILE   
CATH (Classification of proteins structures)1ZD9    2H18    4ILE   
SuperfamilyQ96BM9
Human Protein AtlasENSG00000143862
Peptide AtlasQ96BM9
HPRD09807
IPIIPI00060031   
Protein Interaction databases
DIP (DOE-UCLA)Q96BM9
IntAct (EBI)Q96BM9
FunCoupENSG00000143862
BioGRIDARL8A
STRING (EMBL)ARL8A
ZODIACARL8A
Ontologies - Pathways
QuickGOQ96BM9
Ontology : AmiGOGTPase activity  protein binding  GTP binding  cytoplasm  lysosomal membrane  chromosome segregation  mitotic nuclear division  small GTPase mediated signal transduction  metabolic process  membrane  midbody  late endosome membrane  alpha-tubulin binding  beta-tubulin binding  spindle midzone  cell division  extracellular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  cytoplasm  lysosomal membrane  chromosome segregation  mitotic nuclear division  small GTPase mediated signal transduction  metabolic process  membrane  midbody  late endosome membrane  alpha-tubulin binding  beta-tubulin binding  spindle midzone  cell division  extracellular exosome  
NDEx NetworkARL8A
Atlas of Cancer Signalling NetworkARL8A
Wikipedia pathwaysARL8A
Orthology - Evolution
OrthoDB127829
GeneTree (enSembl)ENSG00000143862
Phylogenetic Trees/Animal Genes : TreeFamARL8A
HOVERGENQ96BM9
HOGENOMQ96BM9
Homologs : HomoloGeneARL8A
Homology/Alignments : Family Browser (UCSC)ARL8A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARL8A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARL8A
dbVarARL8A
ClinVarARL8A
1000_GenomesARL8A 
Exome Variant ServerARL8A
ExAC (Exome Aggregation Consortium)ARL8A (select the gene name)
Genetic variants : HAPMAP127829
Genomic Variants (DGV)ARL8A [DGVbeta]
DECIPHER (Syndromes)1:202102532-202113871  ENSG00000143862
CONAN: Copy Number AnalysisARL8A 
Mutations
ICGC Data PortalARL8A 
TCGA Data PortalARL8A 
Broad Tumor PortalARL8A
OASIS PortalARL8A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARL8A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARL8A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARL8A
DgiDB (Drug Gene Interaction Database)ARL8A
DoCM (Curated mutations)ARL8A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARL8A (select a term)
intoGenARL8A
Cancer3DARL8A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenARL8A
Genetic Testing Registry ARL8A
NextProtQ96BM9 [Medical]
TSGene127829
GENETestsARL8A
Huge Navigator ARL8A [HugePedia]
snp3D : Map Gene to Disease127829
BioCentury BCIQARL8A
ClinGenARL8A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD127829
Chemical/Pharm GKB GenePA134905021
Clinical trialARL8A
Miscellaneous
canSAR (ICR)ARL8A (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARL8A
EVEXARL8A
GoPubMedARL8A
iHOPARL8A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 11:54:58 CET 2017

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