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ARL8B (ADP ribosylation factor like GTPase 8B)

Identity

Alias_namesARL10C
ADP-ribosylation factor-like 10C
ADP-ribosylation factor-like 8B
Alias_symbol (synonym)FLJ10702
Gie1
Other alias
HGNC (Hugo) ARL8B
LocusID (NCBI) 55207
Atlas_Id 60505
Location 3p26.1  [Link to chromosome band 3p26]
Location_base_pair Starts at 5122245 and ends at 5180916 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARL8B (3p26.1) / ITGA2B (17q21.31)BSN (3p21.31) / ARL8B (3p26.1)CCL8 (17q12) / ARL8B (3p26.1)
FSTL1 (3q13.33) / ARL8B (3p26.1)NUDT3 (6p21.31) / ARL8B (3p26.1)RPL23 (17q12) / ARL8B (3p26.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARL8B   25564
Cards
Entrez_Gene (NCBI)ARL8B  55207  ADP ribosylation factor like GTPase 8B
AliasesARL10C; Gie1
GeneCards (Weizmann)ARL8B
Ensembl hg19 (Hinxton)ENSG00000134108 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134108 [Gene_View]  chr3:5122245-5180916 [Contig_View]  ARL8B [Vega]
ICGC DataPortalENSG00000134108
TCGA cBioPortalARL8B
AceView (NCBI)ARL8B
Genatlas (Paris)ARL8B
WikiGenes55207
SOURCE (Princeton)ARL8B
Genetics Home Reference (NIH)ARL8B
Genomic and cartography
GoldenPath hg38 (UCSC)ARL8B  -     chr3:5122245-5180916 +  3p26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARL8B  -     3p26.1   [Description]    (hg19-Feb_2009)
EnsemblARL8B - 3p26.1 [CytoView hg19]  ARL8B - 3p26.1 [CytoView hg38]
Mapping of homologs : NCBIARL8B [Mapview hg19]  ARL8B [Mapview hg38]
OMIM616596   
Gene and transcription
Genbank (Entrez)AB118751 AF086108 AK001564 AK295465 AK298951
RefSeq transcript (Entrez)NM_018184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARL8B
Cluster EST : UnigeneHs.250009 [ NCBI ]
CGAP (NCI)Hs.250009
Alternative Splicing GalleryENSG00000134108
Gene ExpressionARL8B [ NCBI-GEO ]   ARL8B [ EBI - ARRAY_EXPRESS ]   ARL8B [ SEEK ]   ARL8B [ MEM ]
Gene Expression Viewer (FireBrowse)ARL8B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55207
GTEX Portal (Tissue expression)ARL8B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVJ2
Splice isoforms : SwissVarQ9NVJ2
PhosPhoSitePlusQ9NVJ2
Domaine pattern : Prosite (Expaxy)ARF (PS51417)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF    Small_GTPase_ARF/SAR   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)ARL8B
DMDM Disease mutations55207
Blocks (Seattle)ARL8B
PDB (SRS)2AL7   
PDB (PDBSum)2AL7   
PDB (IMB)2AL7   
PDB (RSDB)2AL7   
Structural Biology KnowledgeBase2AL7   
SCOP (Structural Classification of Proteins)2AL7   
CATH (Classification of proteins structures)2AL7   
SuperfamilyQ9NVJ2
Human Protein AtlasENSG00000134108
Peptide AtlasQ9NVJ2
HPRD12483
IPIIPI00940959   IPI00018871   IPI00788984   IPI00793455   IPI00789606   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVJ2
IntAct (EBI)Q9NVJ2
FunCoupENSG00000134108
BioGRIDARL8B
STRING (EMBL)ARL8B
ZODIACARL8B
Ontologies - Pathways
QuickGOQ9NVJ2
Ontology : AmiGOGTPase activity  protein binding  GTP binding  cytoplasm  lysosome  lysosomal membrane  cell cycle  chromosome segregation  small GTPase mediated signal transduction  membrane  GDP binding  midbody  late endosome membrane  lysosome localization  alpha-tubulin binding  beta-tubulin binding  spindle midzone  cell division  extracellular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  cytoplasm  lysosome  lysosomal membrane  cell cycle  chromosome segregation  small GTPase mediated signal transduction  membrane  GDP binding  midbody  late endosome membrane  lysosome localization  alpha-tubulin binding  beta-tubulin binding  spindle midzone  cell division  extracellular exosome  
NDEx NetworkARL8B
Atlas of Cancer Signalling NetworkARL8B
Wikipedia pathwaysARL8B
Orthology - Evolution
OrthoDB55207
GeneTree (enSembl)ENSG00000134108
Phylogenetic Trees/Animal Genes : TreeFamARL8B
HOVERGENQ9NVJ2
HOGENOMQ9NVJ2
Homologs : HomoloGeneARL8B
Homology/Alignments : Family Browser (UCSC)ARL8B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARL8B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARL8B
dbVarARL8B
ClinVarARL8B
1000_GenomesARL8B 
Exome Variant ServerARL8B
ExAC (Exome Aggregation Consortium)ARL8B (select the gene name)
Genetic variants : HAPMAP55207
Genomic Variants (DGV)ARL8B [DGVbeta]
DECIPHERARL8B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARL8B 
Mutations
ICGC Data PortalARL8B 
TCGA Data PortalARL8B 
Broad Tumor PortalARL8B
OASIS PortalARL8B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARL8B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARL8B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARL8B
DgiDB (Drug Gene Interaction Database)ARL8B
DoCM (Curated mutations)ARL8B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARL8B (select a term)
intoGenARL8B
Cancer3DARL8B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616596   
Orphanet
MedgenARL8B
Genetic Testing Registry ARL8B
NextProtQ9NVJ2 [Medical]
TSGene55207
GENETestsARL8B
Target ValidationARL8B
Huge Navigator ARL8B [HugePedia]
snp3D : Map Gene to Disease55207
BioCentury BCIQARL8B
ClinGenARL8B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55207
Chemical/Pharm GKB GenePA134959531
Clinical trialARL8B
Miscellaneous
canSAR (ICR)ARL8B (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARL8B
EVEXARL8B
GoPubMedARL8B
iHOPARL8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:45 CEST 2017

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