Identity
HGNC
LOCATION
1q25.3
LOCUSID
ALIAS
ARC16,dJ127C7.3,p16-Arc
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10092
MIM: 604227
HGNC: 708
Ensembl: ENSG00000162704
Variants:
dbSNP: 10092
ClinVar: 10092
TCGA: ENSG00000162704
COSMIC: ARPC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162704 | ENST00000294742 | O15511 |
| ENSG00000162704 | ENST00000359856 | O15511 |
| ENSG00000162704 | ENST00000367534 | B1ALC0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38744388 | 2024 | TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells. | 0 |
| 38744388 | 2024 | TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells. | 0 |
| 36881291 | 2023 | ARPC5 is transcriptionally activated by KLF4, and promotes cell migration and invasion in prostate cancer via up-regulating ADAM17 : ARPC5 serves as an oncogene in prostate cancer. | 2 |
| 37162507 | 2023 | ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells. | 6 |
| 37349293 | 2023 | Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling. | 2 |
| 37382373 | 2023 | ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality. | 3 |
| 37789267 | 2023 | ARPC5 acts as a potential prognostic biomarker that is associated with cell proliferation, migration and immune infiltrate in gliomas. | 1 |
| 36881291 | 2023 | ARPC5 is transcriptionally activated by KLF4, and promotes cell migration and invasion in prostate cancer via up-regulating ADAM17 : ARPC5 serves as an oncogene in prostate cancer. | 2 |
| 37162507 | 2023 | ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells. | 6 |
| 37349293 | 2023 | Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling. | 2 |
| 37382373 | 2023 | ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality. | 3 |
| 37789267 | 2023 | ARPC5 acts as a potential prognostic biomarker that is associated with cell proliferation, migration and immune infiltrate in gliomas. | 1 |
| 34468072 | 2022 | YAP facilitates melanoma migration through regulation of actin-related protein 2/3 complex subunit 5 (ARPC5). | 9 |
| 34468072 | 2022 | YAP facilitates melanoma migration through regulation of actin-related protein 2/3 complex subunit 5 (ARPC5). | 9 |
| 30201948 | 2018 | The Expression of Actin-Related Protein 2/3 Complex Subunit 5 (ARPC5) Expression in Multiple Myeloma and its Prognostic Significance. | 14 |
Citation
Dessen P
ARPC5 (actin related protein 2/3 complex subunit 5)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52831/arpc5
