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ARPC5 (actin related protein 2/3 complex subunit 5)

Identity

Alias_namesactin related protein 2/3 complex, subunit 5 (16 kD)
actin related protein 2/3 complex subunit 5, 16kDa
Alias_symbol (synonym)p16-Arc
ARC16
dJ127C7.3
Other alias
HGNC (Hugo) ARPC5
LocusID (NCBI) 10092
Atlas_Id 52831
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 183595328 and ends at 183605076 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARPC5 (1q25.3) / FBXO9 (6p12.1)SEC31A (4q21.22) / ARPC5 (1q25.3)UBE2D3 (4q24) / ARPC5 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARPC5   708
Cards
Entrez_Gene (NCBI)ARPC5  10092  actin related protein 2/3 complex subunit 5
AliasesARC16; dJ127C7.3; p16-Arc
GeneCards (Weizmann)ARPC5
Ensembl hg19 (Hinxton)ENSG00000162704 [Gene_View]  chr1:183595328-183605076 [Contig_View]  ARPC5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000162704 [Gene_View]  chr1:183595328-183605076 [Contig_View]  ARPC5 [Vega]
ICGC DataPortalENSG00000162704
TCGA cBioPortalARPC5
AceView (NCBI)ARPC5
Genatlas (Paris)ARPC5
WikiGenes10092
SOURCE (Princeton)ARPC5
Genetics Home Reference (NIH)ARPC5
Genomic and cartography
GoldenPath hg19 (UCSC)ARPC5  -     chr1:183595328-183605076 -  1q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARPC5  -     1q25.3   [Description]    (hg38-Dec_2013)
EnsemblARPC5 - 1q25.3 [CytoView hg19]  ARPC5 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIARPC5 [Mapview hg19]  ARPC5 [Mapview hg38]
OMIM604227   
Gene and transcription
Genbank (Entrez)AF006088 AF017807 AI148784 AK095424 AK129598
RefSeq transcript (Entrez)NM_001270439 NM_005717
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)ARPC5
Cluster EST : UnigeneHs.518609 [ NCBI ]
CGAP (NCI)Hs.518609
Alternative Splicing GalleryENSG00000162704
Gene ExpressionARPC5 [ NCBI-GEO ]   ARPC5 [ EBI - ARRAY_EXPRESS ]   ARPC5 [ SEEK ]   ARPC5 [ MEM ]
Gene Expression Viewer (FireBrowse)ARPC5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10092
GTEX Portal (Tissue expression)ARPC5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15511   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15511  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15511
Splice isoforms : SwissVarO15511
PhosPhoSitePlusO15511
Domains : Interpro (EBI)ARPC5   
Domain families : Pfam (Sanger)P16-Arc (PF04699)   
Domain families : Pfam (NCBI)pfam04699   
Conserved Domain (NCBI)ARPC5
DMDM Disease mutations10092
Blocks (Seattle)ARPC5
SuperfamilyO15511
Human Protein AtlasENSG00000162704
Peptide AtlasO15511
HPRD11969
IPIIPI00550234   IPI00007280   IPI00450866   IPI00640779   
Protein Interaction databases
DIP (DOE-UCLA)O15511
IntAct (EBI)O15511
FunCoupENSG00000162704
BioGRIDARPC5
STRING (EMBL)ARPC5
ZODIACARPC5
Ontologies - Pathways
QuickGOO15511
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  cytoplasm  cytosol  Arp2/3 protein complex  focal adhesion  movement of cell or subcellular component  actin cytoskeleton  cell migration  actin cytoskeleton organization  Arp2/3 complex-mediated actin nucleation  Fc-gamma receptor signaling pathway involved in phagocytosis  cell projection  ephrin receptor signaling pathway  actin filament binding  extracellular exosome  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  cytoplasm  cytosol  Arp2/3 protein complex  focal adhesion  movement of cell or subcellular component  actin cytoskeleton  cell migration  actin cytoskeleton organization  Arp2/3 complex-mediated actin nucleation  Fc-gamma receptor signaling pathway involved in phagocytosis  cell projection  ephrin receptor signaling pathway  actin filament binding  extracellular exosome  
Pathways : KEGGFc gamma R-mediated phagocytosis    Regulation of actin cytoskeleton    Bacterial invasion of epithelial cells    Pathogenic Escherichia coli infection    Shigellosis    Salmonella infection   
NDEx NetworkARPC5
Atlas of Cancer Signalling NetworkARPC5
Wikipedia pathwaysARPC5
Orthology - Evolution
OrthoDB10092
GeneTree (enSembl)ENSG00000162704
Phylogenetic Trees/Animal Genes : TreeFamARPC5
HOVERGENO15511
HOGENOMO15511
Homologs : HomoloGeneARPC5
Homology/Alignments : Family Browser (UCSC)ARPC5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARPC5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARPC5
dbVarARPC5
ClinVarARPC5
1000_GenomesARPC5 
Exome Variant ServerARPC5
ExAC (Exome Aggregation Consortium)ARPC5 (select the gene name)
Genetic variants : HAPMAP10092
Genomic Variants (DGV)ARPC5 [DGVbeta]
DECIPHER (Syndromes)1:183595328-183605076  ENSG00000162704
CONAN: Copy Number AnalysisARPC5 
Mutations
ICGC Data PortalARPC5 
TCGA Data PortalARPC5 
Broad Tumor PortalARPC5
OASIS PortalARPC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARPC5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARPC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARPC5
DgiDB (Drug Gene Interaction Database)ARPC5
DoCM (Curated mutations)ARPC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARPC5 (select a term)
intoGenARPC5
Cancer3DARPC5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604227   
Orphanet
MedgenARPC5
Genetic Testing Registry ARPC5
NextProtO15511 [Medical]
TSGene10092
GENETestsARPC5
Huge Navigator ARPC5 [HugePedia]
snp3D : Map Gene to Disease10092
BioCentury BCIQARPC5
ClinGenARPC5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10092
Chemical/Pharm GKB GenePA25003
Clinical trialARPC5
Miscellaneous
canSAR (ICR)ARPC5 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARPC5
EVEXARPC5
GoPubMedARPC5
iHOPARPC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:56:37 CET 2017

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