ART1 (ADP-ribosyltransferase 1)

2007-09-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
ART2,ARTC1,CD296,RT6
FUSION GENES

Other Information

Locus ID:

NCBI: 417
MIM: 601625
HGNC: 723
Ensembl: ENSG00000129744

Variants:

dbSNP: 417
ClinVar: 417
TCGA: ENSG00000129744
COSMIC: ART1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129744ENST00000250693P52961

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
DefensinsREACTOMER-HSA-1461973
Alpha-defensinsREACTOMER-HSA-1462054
Antimicrobial peptidesREACTOMER-HSA-6803157

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
176141072007Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck.30
166274712006ADP-ribosyltransferase-specific modification of human neutrophil peptide-1.22
252923372015ARTC1-mediated ADP-ribosylation of GRP78/BiP: a new player in endoplasmic-reticulum stress responses.13
272778352016Regulation of the RhoA/ROCK/AKT/β-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.6
268477182016Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.4
274660782016Expression of ADP-ribosyltransferase 1 Is Associated with Poor Prognosis of Glioma Patients.4
263070002016Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets.3

Citation

Dessen P

ART1 (ADP-ribosyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-09-01

Online version: http://atlasgeneticsoncology.org/gene/49747/art1