Atlas of Genetics and Cytogenetics in Oncology and Haematology


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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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ARX (aristaless related homeobox)

Identity

Other namesCT121
EIEE1
ISSX
MRX29
MRX32
MRX33
MRX36
MRX38
MRX43
MRX54
MRX76
MRX87
MRXS1
PRTS
HGNC (Hugo) ARX
LocusID (NCBI) 170302
Location Xp21.3
Location_base_pair Starts at 25021813 and ends at 25034065 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ARX   18060
Cards
Entrez_Gene (NCBI)ARX  170302  aristaless related homeobox
GeneCards (Weizmann)ARX
Ensembl hg19 (Hinxton)ENSG00000004848 [Gene_View]  chrX:25021813-25034065 [Contig_View]  ARX [Vega]
Ensembl hg38 (Hinxton)ENSG00000004848 [Gene_View]  chrX:25021813-25034065 [Contig_View]  ARX [Vega]
ICGC DataPortalENSG00000004848
cBioPortalARX
AceView (NCBI)ARX
Genatlas (Paris)ARX
WikiGenes170302
SOURCE (Princeton)ARX
Genomic and cartography
GoldenPath hg19 (UCSC)ARX  -     chrX:25021813-25034065 -  Xp21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ARX  -     Xp21.3   [Description]    (hg38-Dec_2013)
EnsemblARX - Xp21.3 [CytoView hg19]  ARX - Xp21.3 [CytoView hg38]
Mapping of homologs : NCBIARX [Mapview hg19]  ARX [Mapview hg38]
OMIM300004   300215   300382   300419   308350   309510   
Gene and transcription
Genbank (Entrez)AA484051 AY038071 BC169333 BC169334 BF196892
RefSeq transcript (Entrez)NM_139058
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_008281 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)ARX
Cluster EST : UnigeneHs.300304 [ NCBI ]
CGAP (NCI)Hs.300304
Alternative Splicing : Fast-db (Paris)GSHG0032021
Alternative Splicing GalleryENSG00000004848
Gene ExpressionARX [ NCBI-GEO ]     ARX [ SEEK ]   ARX [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QS3 (Uniprot)
NextProtQ96QS3  [Medical]
With graphics : InterProQ96QS3
Splice isoforms : SwissVarQ96QS3 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    OAR (PS50803)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeodomain-like    OAR_dom   
Related proteins : CluSTrQ96QS3
Domain families : Pfam (Sanger)Homeobox (PF00046)    OAR (PF03826)   
Domain families : Pfam (NCBI)pfam00046    pfam03826   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations170302
Blocks (Seattle)Q96QS3
Human Protein AtlasENSG00000004848
Peptide AtlasQ96QS3
HPRD02307
IPIIPI00045066   
Protein Interaction databases
DIP (DOE-UCLA)Q96QS3
IntAct (EBI)Q96QS3
FunCoupENSG00000004848
BioGRIDARX
IntegromeDBARX
STRING (EMBL)ARX
Ontologies - Pathways
QuickGOQ96QS3
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  chromatin binding  nucleus  transcription, DNA-templated  axon guidance  globus pallidus development  cerebral cortex tangential migration  embryonic olfactory bulb interneuron precursor migration  cell proliferation in forebrain  cerebral cortex GABAergic interneuron migration  regulation of cell proliferation  lipid digestion  positive regulation of organ growth  epithelial cell fate commitment  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  chromatin binding  nucleus  transcription, DNA-templated  axon guidance  globus pallidus development  cerebral cortex tangential migration  embryonic olfactory bulb interneuron precursor migration  cell proliferation in forebrain  cerebral cortex GABAergic interneuron migration  regulation of cell proliferation  lipid digestion  positive regulation of organ growth  epithelial cell fate commitment  
Protein Interaction DatabaseARX
DoCM (Curated mutations)ARX
Wikipedia pathwaysARX
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerARX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARX
dbVarARX
ClinVarARX
1000_GenomesARX 
Exome Variant ServerARX
SNP (GeneSNP Utah)ARX
SNP : HGBaseARX
Genetic variants : HAPMAPARX
Genomic Variants (DGV)ARX [DGVbeta]
Mutations
ICGC Data PortalENSG00000004848 
Somatic Mutations in Cancer : COSMICARX 
CONAN: Copy Number AnalysisARX 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:25021813-25034065
Mutations and Diseases : HGMDARX
OMIM300004    300215    300382    300419    308350    309510   
MedgenARX
NextProtQ96QS3 [Medical]
GENETestsARX
Disease Genetic AssociationARX
Huge Navigator ARX [HugePedia]  ARX [HugeCancerGEM]
snp3D : Map Gene to Disease170302
DGIdb (Drug Gene Interaction db)ARX
General knowledge
Homologs : HomoloGeneARX
Homology/Alignments : Family Browser (UCSC)ARX
Phylogenetic Trees/Animal Genes : TreeFamARX
Chemical/Protein Interactions : CTD170302
Chemical/Pharm GKB GenePA25024
Clinical trialARX
Cancer Resource (Charite)ENSG00000004848
Other databases
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
CoreMineARX
GoPubMedARX
iHOPARX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 14:46:04 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.