Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2)

Identity

Alias_namesDDEF2
development and differentiation enhancing factor 2
Alias_symbol (synonym)KIAA0400
PAP
SHAG1
CENTB3
Other aliasAMAP2
PAG3
Pap-alpha
HGNC (Hugo) ASAP2
LocusID (NCBI) 8853
Atlas_Id 60547
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 9206765 and ends at 9405683 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASAP2 (2p25.1) / ASAP2 (2p25.1)ASAP2 (2p25.1) / LOC729852 ()ASAP2 (2p25.1) / USP11 (Xp11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASAP2   2721
Cards
Entrez_Gene (NCBI)ASAP2  8853  ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
AliasesAMAP2; CENTB3; DDEF2; PAG3; 
PAP; Pap-alpha; SHAG1
GeneCards (Weizmann)ASAP2
Ensembl hg19 (Hinxton)ENSG00000151693 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151693 [Gene_View]  chr2:9206765-9405683 [Contig_View]  ASAP2 [Vega]
ICGC DataPortalENSG00000151693
TCGA cBioPortalASAP2
AceView (NCBI)ASAP2
Genatlas (Paris)ASAP2
WikiGenes8853
SOURCE (Princeton)ASAP2
Genetics Home Reference (NIH)ASAP2
Genomic and cartography
GoldenPath hg38 (UCSC)ASAP2  -     chr2:9206765-9405683 +  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASAP2  -     2p25.1   [Description]    (hg19-Feb_2009)
EnsemblASAP2 - 2p25.1 [CytoView hg19]  ASAP2 - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBIASAP2 [Mapview hg19]  ASAP2 [Mapview hg38]
OMIM603817   
Gene and transcription
Genbank (Entrez)AA918883 AB007860 AK091121 AK123185 AK124900
RefSeq transcript (Entrez)NM_001135191 NM_003887
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASAP2
Cluster EST : UnigeneHs.555902 [ NCBI ]
CGAP (NCI)Hs.555902
Alternative Splicing GalleryENSG00000151693
Gene ExpressionASAP2 [ NCBI-GEO ]   ASAP2 [ EBI - ARRAY_EXPRESS ]   ASAP2 [ SEEK ]   ASAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)ASAP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8853
GTEX Portal (Tissue expression)ASAP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43150   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43150  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43150
Splice isoforms : SwissVarO43150
PhosPhoSitePlusO43150
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    ARFGAP (PS50115)    PH_DOMAIN (PS50003)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR-dom    Ankyrin_rpt    Ankyrin_rpt-contain_dom    ArfGAP    PH_dom-like    PH_domain    SH3_domain   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    ArfGap (PF01412)    PH (PF00169)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam12796    pfam01412    pfam00169    pfam14604   
Domain families : Smart (EMBL)ANK (SM00248)  ArfGap (SM00105)  PH (SM00233)  SH3 (SM00326)  
Conserved Domain (NCBI)ASAP2
DMDM Disease mutations8853
Blocks (Seattle)ASAP2
SuperfamilyO43150
Human Protein AtlasENSG00000151693
Peptide AtlasO43150
HPRD04820
IPIIPI00022058   IPI00409613   
Protein Interaction databases
DIP (DOE-UCLA)O43150
IntAct (EBI)O43150
FunCoupENSG00000151693
BioGRIDASAP2
STRING (EMBL)ASAP2
ZODIACASAP2
Ontologies - Pathways
QuickGOO43150
Ontology : AmiGOGTPase activator activity  protein binding  plasma membrane  Golgi cisterna membrane  positive regulation of GTPase activity  metal ion binding  
Ontology : EGO-EBIGTPase activator activity  protein binding  plasma membrane  Golgi cisterna membrane  positive regulation of GTPase activity  metal ion binding  
Pathways : BIOCARTAADP-Ribosylation Factor [Genes]   
Pathways : KEGGEndocytosis    Fc gamma R-mediated phagocytosis   
NDEx NetworkASAP2
Atlas of Cancer Signalling NetworkASAP2
Wikipedia pathwaysASAP2
Orthology - Evolution
OrthoDB8853
GeneTree (enSembl)ENSG00000151693
Phylogenetic Trees/Animal Genes : TreeFamASAP2
HOVERGENO43150
HOGENOMO43150
Homologs : HomoloGeneASAP2
Homology/Alignments : Family Browser (UCSC)ASAP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASAP2
dbVarASAP2
ClinVarASAP2
1000_GenomesASAP2 
Exome Variant ServerASAP2
ExAC (Exome Aggregation Consortium)ASAP2 (select the gene name)
Genetic variants : HAPMAP8853
Genomic Variants (DGV)ASAP2 [DGVbeta]
DECIPHERASAP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASAP2 
Mutations
ICGC Data PortalASAP2 
TCGA Data PortalASAP2 
Broad Tumor PortalASAP2
OASIS PortalASAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASAP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASAP2
DgiDB (Drug Gene Interaction Database)ASAP2
DoCM (Curated mutations)ASAP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASAP2 (select a term)
intoGenASAP2
Cancer3DASAP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603817   
Orphanet
MedgenASAP2
Genetic Testing Registry ASAP2
NextProtO43150 [Medical]
TSGene8853
GENETestsASAP2
Target ValidationASAP2
Huge Navigator ASAP2 [HugePedia]
snp3D : Map Gene to Disease8853
BioCentury BCIQASAP2
ClinGenASAP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8853
Chemical/Pharm GKB GenePA164716118
Clinical trialASAP2
Miscellaneous
canSAR (ICR)ASAP2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASAP2
EVEXASAP2
GoPubMedASAP2
iHOPASAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:01:51 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.