ASB11 (ankyrin repeat and SOCS box containing 11)

2014-11-01 Affiliation

Identity

HGNC

ASB11

LOCATION

Xp22.2

LOCUSID

140456

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 140456
MIM: 300626
HGNC: 17186
Ensembl: ENSG00000165192

Variants:

dbSNP: 140456
ClinVar: 140456
TCGA: ENSG00000165192
COSMIC: ASB11

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000165192	ENST00000344384	Q8WXH4
ENSG00000165192	ENST00000380470	Q8WXH4
ENSG00000165192	ENST00000480796	Q8WXH4
ENSG00000165192	ENST00000485437	F8WF31

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
Class I MHC mediated antigen processing & presentation	REACTOME	R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation	REACTOME	R-HSA-983168

References

Pubmed ID	Year	Title	Citations
24337577	2014	Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.	15
31387940	2019	BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress.	0

Citation

Dessen P

ASB11 (ankyrin repeat and SOCS box containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60550/asb11