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ASB2 (ankyrin repeat and SOCS box containing 2)

Identity

Alias_namesankyrin repeat and SOCS box-containing 2
Alias_symbol (synonym)ASB-2
HGNC (Hugo) ASB2
LocusID (NCBI) 51676
Atlas_Id 711
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 94400499 and ends at 94443076 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EFCAB11 (14q32.11) / ASB2 (14q32.12)EFCAB11 14q32.11 / ASB2 14q32.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASB2   16012
Cards
Entrez_Gene (NCBI)ASB2  51676  ankyrin repeat and SOCS box containing 2
AliasesASB-2
GeneCards (Weizmann)ASB2
Ensembl hg19 (Hinxton)ENSG00000100628 [Gene_View]  chr14:94400499-94443076 [Contig_View]  ASB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100628 [Gene_View]  chr14:94400499-94443076 [Contig_View]  ASB2 [Vega]
ICGC DataPortalENSG00000100628
TCGA cBioPortalASB2
AceView (NCBI)ASB2
Genatlas (Paris)ASB2
WikiGenes51676
SOURCE (Princeton)ASB2
Genetics Home Reference (NIH)ASB2
Genomic and cartography
GoldenPath hg19 (UCSC)ASB2  -     chr14:94400499-94443076 -  14q32.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ASB2  -     14q32.12   [Description]    (hg38-Dec_2013)
EnsemblASB2 - 14q32.12 [CytoView hg19]  ASB2 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBIASB2 [Mapview hg19]  ASB2 [Mapview hg38]
OMIM605759   
Gene and transcription
Genbank (Entrez)AB056723 AB488462 AF159164 AJ251238 AK002049
RefSeq transcript (Entrez)NM_001202429 NM_016150
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NT_187601 NW_004929393
Consensus coding sequences : CCDS (NCBI)ASB2
Cluster EST : UnigeneHs.510327 [ NCBI ]
CGAP (NCI)Hs.510327
Alternative Splicing GalleryENSG00000100628
Gene ExpressionASB2 [ NCBI-GEO ]   ASB2 [ EBI - ARRAY_EXPRESS ]   ASB2 [ SEEK ]   ASB2 [ MEM ]
Gene Expression Viewer (FireBrowse)ASB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51676
GTEX Portal (Tissue expression)ASB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96Q27   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96Q27  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96Q27
Splice isoforms : SwissVarQ96Q27
PhosPhoSitePlusQ96Q27
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    SOCS (PS50225)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    SOCS_box   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    Ank_3 (PF13606)    SOCS_box (PF07525)   
Domain families : Pfam (NCBI)pfam12796    pfam13606    pfam07525   
Domain families : Smart (EMBL)ANK (SM00248)  SOCS_box (SM00969)  
Conserved Domain (NCBI)ASB2
DMDM Disease mutations51676
Blocks (Seattle)ASB2
SuperfamilyQ96Q27
Human Protein AtlasENSG00000100628
Peptide AtlasQ96Q27
HPRD05768
IPIIPI00939922   IPI00216028   IPI01016013   IPI01025210   IPI01025320   IPI01024952   IPI01025129   IPI01024720   
Protein Interaction databases
DIP (DOE-UCLA)Q96Q27
IntAct (EBI)Q96Q27
FunCoupENSG00000100628
BioGRIDASB2
STRING (EMBL)ASB2
ZODIACASB2
Ontologies - Pathways
QuickGOQ96Q27
Ontology : AmiGOprotein polyubiquitination  positive regulation of defense response to virus by host  protein binding  signal transduction  Cul5-RING ubiquitin ligase complex  intracellular signal transduction  skeletal muscle cell differentiation  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  myoblast differentiation  ubiquitin protein ligase activity  mitophagy in response to mitochondrial depolarization  xenophagy  
Ontology : EGO-EBIprotein polyubiquitination  positive regulation of defense response to virus by host  protein binding  signal transduction  Cul5-RING ubiquitin ligase complex  intracellular signal transduction  skeletal muscle cell differentiation  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  myoblast differentiation  ubiquitin protein ligase activity  mitophagy in response to mitochondrial depolarization  xenophagy  
NDEx NetworkASB2
Atlas of Cancer Signalling NetworkASB2
Wikipedia pathwaysASB2
Orthology - Evolution
OrthoDB51676
GeneTree (enSembl)ENSG00000100628
Phylogenetic Trees/Animal Genes : TreeFamASB2
HOVERGENQ96Q27
HOGENOMQ96Q27
Homologs : HomoloGeneASB2
Homology/Alignments : Family Browser (UCSC)ASB2
Gene fusions - Rearrangements
Fusion : MitelmanEFCAB11/ASB2 [14q32.11/14q32.12]  [t(14;14)(q32;q32)]  
Fusion: TCGAEFCAB11 14q32.11 ASB2 14q32.12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASB2
dbVarASB2
ClinVarASB2
1000_GenomesASB2 
Exome Variant ServerASB2
ExAC (Exome Aggregation Consortium)ASB2 (select the gene name)
Genetic variants : HAPMAP51676
Genomic Variants (DGV)ASB2 [DGVbeta]
DECIPHER (Syndromes)14:94400499-94443076  ENSG00000100628
CONAN: Copy Number AnalysisASB2 
Mutations
ICGC Data PortalASB2 
TCGA Data PortalASB2 
Broad Tumor PortalASB2
OASIS PortalASB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASB2
DgiDB (Drug Gene Interaction Database)ASB2
DoCM (Curated mutations)ASB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASB2 (select a term)
intoGenASB2
Cancer3DASB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605759   
Orphanet
MedgenASB2
Genetic Testing Registry ASB2
NextProtQ96Q27 [Medical]
TSGene51676
GENETestsASB2
Huge Navigator ASB2 [HugePedia]
snp3D : Map Gene to Disease51676
BioCentury BCIQASB2
ClinGenASB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51676
Chemical/Pharm GKB GenePA25030
Clinical trialASB2
Miscellaneous
canSAR (ICR)ASB2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASB2
EVEXASB2
GoPubMedASB2
iHOPASB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Nov 18 19:31:32 CET 2016

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