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ASCC2 (activating signal cointegrator 1 complex subunit 2)

Identity

Alias_symbol (synonym)ASC1p100
FLJ21588
DKFZp586O0223
Other aliasp100
HGNC (Hugo) ASCC2
LocusID (NCBI) 84164
Atlas_Id 55161
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 30184597 and ends at 30234293 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ASCC2 (22q12.2) / ASCC2 (22q12.2)ASCC2 (22q12.2) / EZR (6q25.3)ASCC2 (22q12.2) / FOXP4 (6p21.1)
ASCC2 (22q12.2) / LAMTOR3 (4q23)CD74 (5q32) / ASCC2 (22q12.2)EIF3L (22q13.1) / ASCC2 (22q12.2)
ZMAT5 (22q12.2) / ASCC2 (22q12.2)ZNRF3 (22q12.1) / ASCC2 (22q12.2)EIF3L 22q13.1 / ASCC2 22q12.2
ZMAT5 22q12.2 / ASCC2 22q12.2ZNRF3 22q12.1 / ASCC2 22q12.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASCC2   24103
Cards
Entrez_Gene (NCBI)ASCC2  84164  activating signal cointegrator 1 complex subunit 2
AliasesASC1p100; p100
GeneCards (Weizmann)ASCC2
Ensembl hg19 (Hinxton)ENSG00000100325 [Gene_View]  chr22:30184597-30234293 [Contig_View]  ASCC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100325 [Gene_View]  chr22:30184597-30234293 [Contig_View]  ASCC2 [Vega]
ICGC DataPortalENSG00000100325
TCGA cBioPortalASCC2
AceView (NCBI)ASCC2
Genatlas (Paris)ASCC2
WikiGenes84164
SOURCE (Princeton)ASCC2
Genetics Home Reference (NIH)ASCC2
Genomic and cartography
GoldenPath hg19 (UCSC)ASCC2  -     chr22:30184597-30234293 -  22q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ASCC2  -     22q12.2   [Description]    (hg38-Dec_2013)
EnsemblASCC2 - 22q12.2 [CytoView hg19]  ASCC2 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBIASCC2 [Mapview hg19]  ASCC2 [Mapview hg38]
OMIM614216   
Gene and transcription
Genbank (Entrez)AA765659 AK022886 AK025241 AK222723 AK223033
RefSeq transcript (Entrez)NM_001242906 NM_032204
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)ASCC2
Cluster EST : UnigeneHs.731754 [ NCBI ]
CGAP (NCI)Hs.731754
Alternative Splicing GalleryENSG00000100325
Gene ExpressionASCC2 [ NCBI-GEO ]   ASCC2 [ EBI - ARRAY_EXPRESS ]   ASCC2 [ SEEK ]   ASCC2 [ MEM ]
Gene Expression Viewer (FireBrowse)ASCC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84164
GTEX Portal (Tissue expression)ASCC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1I8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1I8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1I8
Splice isoforms : SwissVarQ9H1I8
PhosPhoSitePlusQ9H1I8
Domaine pattern : Prosite (Expaxy)CUE (PS51140)   
Domains : Interpro (EBI)CUE    UBA-like   
Domain families : Pfam (Sanger)CUE (PF02845)   
Domain families : Pfam (NCBI)pfam02845   
Domain families : Smart (EMBL)CUE (SM00546)  
Conserved Domain (NCBI)ASCC2
DMDM Disease mutations84164
Blocks (Seattle)ASCC2
PDB (SRS)2DI0   
PDB (PDBSum)2DI0   
PDB (IMB)2DI0   
PDB (RSDB)2DI0   
Structural Biology KnowledgeBase2DI0   
SCOP (Structural Classification of Proteins)2DI0   
CATH (Classification of proteins structures)2DI0   
SuperfamilyQ9H1I8
Human Protein AtlasENSG00000100325
Peptide AtlasQ9H1I8
HPRD16515
IPIIPI00549736   IPI00452803   IPI01015732   IPI00893854   IPI00894003   IPI00894241   IPI00892691   IPI00889573   IPI00892912   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1I8
IntAct (EBI)Q9H1I8
FunCoupENSG00000100325
BioGRIDASCC2
STRING (EMBL)ASCC2
ZODIACASCC2
Ontologies - Pathways
QuickGOQ9H1I8
Ontology : AmiGOnucleoplasm  DNA dealkylation involved in DNA repair  transcription, DNA-templated  regulation of transcription, DNA-templated  
Ontology : EGO-EBInucleoplasm  DNA dealkylation involved in DNA repair  transcription, DNA-templated  regulation of transcription, DNA-templated  
NDEx NetworkASCC2
Atlas of Cancer Signalling NetworkASCC2
Wikipedia pathwaysASCC2
Orthology - Evolution
OrthoDB84164
GeneTree (enSembl)ENSG00000100325
Phylogenetic Trees/Animal Genes : TreeFamASCC2
HOVERGENQ9H1I8
HOGENOMQ9H1I8
Homologs : HomoloGeneASCC2
Homology/Alignments : Family Browser (UCSC)ASCC2
Gene fusions - Rearrangements
Fusion : MitelmanEIF3L/ASCC2 [22q13.1/22q12.2]  [t(22;22)(q12;q13)]  
Fusion : MitelmanZMAT5/ASCC2 [22q12.2/22q12.2]  [t(22;22)(q12;q12)]  
Fusion : MitelmanZNRF3/ASCC2 [22q12.1/22q12.2]  [t(22;22)(q12;q12)]  
Fusion: TCGAEIF3L 22q13.1 ASCC2 22q12.2 LUAD
Fusion: TCGAZMAT5 22q12.2 ASCC2 22q12.2 GBM
Fusion: TCGAZNRF3 22q12.1 ASCC2 22q12.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASCC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASCC2
dbVarASCC2
ClinVarASCC2
1000_GenomesASCC2 
Exome Variant ServerASCC2
ExAC (Exome Aggregation Consortium)ASCC2 (select the gene name)
Genetic variants : HAPMAP84164
Genomic Variants (DGV)ASCC2 [DGVbeta]
DECIPHER (Syndromes)22:30184597-30234293  ENSG00000100325
CONAN: Copy Number AnalysisASCC2 
Mutations
ICGC Data PortalASCC2 
TCGA Data PortalASCC2 
Broad Tumor PortalASCC2
OASIS PortalASCC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASCC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASCC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASCC2
DgiDB (Drug Gene Interaction Database)ASCC2
DoCM (Curated mutations)ASCC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASCC2 (select a term)
intoGenASCC2
Cancer3DASCC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614216   
Orphanet
MedgenASCC2
Genetic Testing Registry ASCC2
NextProtQ9H1I8 [Medical]
TSGene84164
GENETestsASCC2
Huge Navigator ASCC2 [HugePedia]
snp3D : Map Gene to Disease84164
BioCentury BCIQASCC2
ClinGenASCC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84164
Chemical/Pharm GKB GenePA134916940
Clinical trialASCC2
Miscellaneous
canSAR (ICR)ASCC2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASCC2
EVEXASCC2
GoPubMedASCC2
iHOPASCC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:53:11 CEST 2017

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