Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ASCL4 (achaete-scute family bHLH transcription factor 4)

Identity

Alias_namesachaete-scute complex-like 4 (Drosophila)
achaete-scute complex homolog 4 (Drosophila)
Alias_symbol (synonym)HASH4
bHLHa44
Other alias
HGNC (Hugo) ASCL4
LocusID (NCBI) 121549
Atlas_Id 60568
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 107774385 and ends at 107776644 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASCL4   24311
Cards
Entrez_Gene (NCBI)ASCL4  121549  achaete-scute family bHLH transcription factor 4
AliasesHASH4; bHLHa44
GeneCards (Weizmann)ASCL4
Ensembl hg19 (Hinxton)ENSG00000187855 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187855 [Gene_View]  chr12:107774385-107776644 [Contig_View]  ASCL4 [Vega]
ICGC DataPortalENSG00000187855
TCGA cBioPortalASCL4
AceView (NCBI)ASCL4
Genatlas (Paris)ASCL4
WikiGenes121549
SOURCE (Princeton)ASCL4
Genetics Home Reference (NIH)ASCL4
Genomic and cartography
GoldenPath hg38 (UCSC)ASCL4  -     chr12:107774385-107776644 +  12q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASCL4  -     12q23.3   [Description]    (hg19-Feb_2009)
EnsemblASCL4 - 12q23.3 [CytoView hg19]  ASCL4 - 12q23.3 [CytoView hg38]
Mapping of homologs : NCBIASCL4 [Mapview hg19]  ASCL4 [Mapview hg38]
OMIM609155   
Gene and transcription
Genbank (Entrez)AI290227 AY238895 BC128211 BC128212 BK000275
RefSeq transcript (Entrez)NM_203436
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASCL4
Cluster EST : UnigeneHs.149910 [ NCBI ]
CGAP (NCI)Hs.149910
Alternative Splicing GalleryENSG00000187855
Gene ExpressionASCL4 [ NCBI-GEO ]   ASCL4 [ EBI - ARRAY_EXPRESS ]   ASCL4 [ SEEK ]   ASCL4 [ MEM ]
Gene Expression Viewer (FireBrowse)ASCL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121549
GTEX Portal (Tissue expression)ASCL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6XD76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6XD76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6XD76
Splice isoforms : SwissVarQ6XD76
PhosPhoSitePlusQ6XD76
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)Achaete-scute-rel    bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)ASCL4
DMDM Disease mutations121549
Blocks (Seattle)ASCL4
SuperfamilyQ6XD76
Human Protein AtlasENSG00000187855
Peptide AtlasQ6XD76
HPRD12374
IPIIPI00069167   
Protein Interaction databases
DIP (DOE-UCLA)Q6XD76
IntAct (EBI)Q6XD76
FunCoupENSG00000187855
BioGRIDASCL4
STRING (EMBL)ASCL4
ZODIACASCL4
Ontologies - Pathways
QuickGOQ6XD76
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  cellular_component  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  regulation of transcription from RNA polymerase II promoter  skin development  protein dimerization activity  RNA polymerase II transcription factor complex  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  cellular_component  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  regulation of transcription from RNA polymerase II promoter  skin development  protein dimerization activity  RNA polymerase II transcription factor complex  
NDEx NetworkASCL4
Atlas of Cancer Signalling NetworkASCL4
Wikipedia pathwaysASCL4
Orthology - Evolution
OrthoDB121549
GeneTree (enSembl)ENSG00000187855
Phylogenetic Trees/Animal Genes : TreeFamASCL4
HOVERGENQ6XD76
HOGENOMQ6XD76
Homologs : HomoloGeneASCL4
Homology/Alignments : Family Browser (UCSC)ASCL4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASCL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASCL4
dbVarASCL4
ClinVarASCL4
1000_GenomesASCL4 
Exome Variant ServerASCL4
ExAC (Exome Aggregation Consortium)ASCL4 (select the gene name)
Genetic variants : HAPMAP121549
Genomic Variants (DGV)ASCL4 [DGVbeta]
DECIPHERASCL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASCL4 
Mutations
ICGC Data PortalASCL4 
TCGA Data PortalASCL4 
Broad Tumor PortalASCL4
OASIS PortalASCL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASCL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASCL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASCL4
DgiDB (Drug Gene Interaction Database)ASCL4
DoCM (Curated mutations)ASCL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASCL4 (select a term)
intoGenASCL4
Cancer3DASCL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609155   
Orphanet
MedgenASCL4
Genetic Testing Registry ASCL4
NextProtQ6XD76 [Medical]
TSGene121549
GENETestsASCL4
Target ValidationASCL4
Huge Navigator ASCL4 [HugePedia]
snp3D : Map Gene to Disease121549
BioCentury BCIQASCL4
ClinGenASCL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD121549
Chemical/Pharm GKB GenePA134869300
Clinical trialASCL4
Miscellaneous
canSAR (ICR)ASCL4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASCL4
EVEXASCL4
GoPubMedASCL4
iHOPASCL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:01:54 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.