Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ASF1A (anti-silencing function 1A histone chaperone)

Identity

Alias_namesASF1 anti-silencing function 1 homolog A (S. cerevisiae)
Alias_symbol (synonym)DKFZP547E2110
CIA
Other aliasCGI-98
HSPC146
HGNC (Hugo) ASF1A
LocusID (NCBI) 25842
Atlas_Id 45707
Location 6q22.31  [Link to chromosome band 6q22]
Location_base_pair Starts at 118894077 and ends at 118909170 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ASF1A   20995
Cards
Entrez_Gene (NCBI)ASF1A  25842  anti-silencing function 1A histone chaperone
AliasesCGI-98; CIA; HSPC146
GeneCards (Weizmann)ASF1A
Ensembl hg19 (Hinxton)ENSG00000111875 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111875 [Gene_View]  ENSG00000111875 [Sequence]  chr6:118894077-118909170 [Contig_View]  ASF1A [Vega]
ICGC DataPortalENSG00000111875
TCGA cBioPortalASF1A
AceView (NCBI)ASF1A
Genatlas (Paris)ASF1A
WikiGenes25842
SOURCE (Princeton)ASF1A
Genetics Home Reference (NIH)ASF1A
Genomic and cartography
GoldenPath hg38 (UCSC)ASF1A  -     chr6:118894077-118909170 +  6q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASF1A  -     6q22.31   [Description]    (hg19-Feb_2009)
EnsemblASF1A - 6q22.31 [CytoView hg19]  ASF1A - 6q22.31 [CytoView hg38]
Mapping of homologs : NCBIASF1A [Mapview hg19]  ASF1A [Mapview hg38]
OMIM609189   
Gene and transcription
Genbank (Entrez)AA481056 AB028628 AF151856 AF161495 AF279306
RefSeq transcript (Entrez)NM_014034
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASF1A
Cluster EST : UnigeneHs.292316 [ NCBI ]
CGAP (NCI)Hs.292316
Alternative Splicing GalleryENSG00000111875
Gene ExpressionASF1A [ NCBI-GEO ]   ASF1A [ EBI - ARRAY_EXPRESS ]   ASF1A [ SEEK ]   ASF1A [ MEM ]
Gene Expression Viewer (FireBrowse)ASF1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25842
GTEX Portal (Tissue expression)ASF1A
Human Protein AtlasENSG00000111875-ASF1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y294   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y294  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y294
Splice isoforms : SwissVarQ9Y294
PhosPhoSitePlusQ9Y294
Domains : Interpro (EBI)ASF1-like    ASF1-like_sf   
Domain families : Pfam (Sanger)ASF1_hist_chap (PF04729)   
Domain families : Pfam (NCBI)pfam04729   
Conserved Domain (NCBI)ASF1A
DMDM Disease mutations25842
Blocks (Seattle)ASF1A
PDB (SRS)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
PDB (PDBSum)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
PDB (IMB)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
PDB (RSDB)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
Structural Biology KnowledgeBase1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
SCOP (Structural Classification of Proteins)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
CATH (Classification of proteins structures)1TEY    2I32    2IIJ    2IO5    3AAD    5C3I   
SuperfamilyQ9Y294
Human Protein Atlas [tissue]ENSG00000111875-ASF1A [tissue]
Peptide AtlasQ9Y294
HPRD16459
IPIIPI00292168   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y294
IntAct (EBI)Q9Y294
FunCoupENSG00000111875
BioGRIDASF1A
STRING (EMBL)ASF1A
ZODIACASF1A
Ontologies - Pathways
QuickGOQ9Y294
Ontology : AmiGOnuclear chromatin  osteoblast differentiation  chromatin binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  DNA repair  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  negative regulation of chromatin silencing  protein-containing complex  histone binding  muscle cell differentiation  
Ontology : EGO-EBInuclear chromatin  osteoblast differentiation  chromatin binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  DNA repair  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  negative regulation of chromatin silencing  protein-containing complex  histone binding  muscle cell differentiation  
NDEx NetworkASF1A
Atlas of Cancer Signalling NetworkASF1A
Wikipedia pathwaysASF1A
Orthology - Evolution
OrthoDB25842
GeneTree (enSembl)ENSG00000111875
Phylogenetic Trees/Animal Genes : TreeFamASF1A
HOGENOMQ9Y294
Homologs : HomoloGeneASF1A
Homology/Alignments : Family Browser (UCSC)ASF1A
Gene fusions - Rearrangements
Fusion : QuiverASF1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASF1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASF1A
dbVarASF1A
ClinVarASF1A
1000_GenomesASF1A 
Exome Variant ServerASF1A
ExAC (Exome Aggregation Consortium)ENSG00000111875
GNOMAD BrowserENSG00000111875
Varsome BrowserASF1A
Genetic variants : HAPMAP25842
Genomic Variants (DGV)ASF1A [DGVbeta]
DECIPHERASF1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASF1A 
Mutations
ICGC Data PortalASF1A 
TCGA Data PortalASF1A 
Broad Tumor PortalASF1A
OASIS PortalASF1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASF1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASF1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASF1A
DgiDB (Drug Gene Interaction Database)ASF1A
DoCM (Curated mutations)ASF1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASF1A (select a term)
intoGenASF1A
Cancer3DASF1A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609189   
Orphanet
DisGeNETASF1A
MedgenASF1A
Genetic Testing Registry ASF1A
NextProtQ9Y294 [Medical]
TSGene25842
GENETestsASF1A
Target ValidationASF1A
Huge Navigator ASF1A [HugePedia]
snp3D : Map Gene to Disease25842
BioCentury BCIQASF1A
ClinGenASF1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25842
Chemical/Pharm GKB GenePA128394636
Clinical trialASF1A
Miscellaneous
canSAR (ICR)ASF1A (select the gene name)
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASF1A
EVEXASF1A
GoPubMedASF1A
iHOPASF1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Dec 21 15:06:23 CET 2018
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