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ASIC4 (acid sensing ion channel subunit family member 4)

Identity

Alias_namesACCN4
amiloride-sensitive cation channel 4, pituitary
acid-sensing (proton-gated) ion channel family member 4
acid sensing ion channel family member 4
Alias_symbol (synonym)BNAC4
Other alias
HGNC (Hugo) ASIC4
LocusID (NCBI) 55515
Atlas_Id 60573
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 219514170 and ends at 219538772 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLCN3 (4q33) / ASIC4 (2q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASIC4   21263
Cards
Entrez_Gene (NCBI)ASIC4  55515  acid sensing ion channel subunit family member 4
AliasesACCN4; BNAC4
GeneCards (Weizmann)ASIC4
Ensembl hg19 (Hinxton)ENSG00000072182 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000072182 [Gene_View]  chr2:219514170-219538772 [Contig_View]  ASIC4 [Vega]
ICGC DataPortalENSG00000072182
TCGA cBioPortalASIC4
AceView (NCBI)ASIC4
Genatlas (Paris)ASIC4
WikiGenes55515
SOURCE (Princeton)ASIC4
Genetics Home Reference (NIH)ASIC4
Genomic and cartography
GoldenPath hg38 (UCSC)ASIC4  -     chr2:219514170-219538772 +  2q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASIC4  -     2q35   [Description]    (hg19-Feb_2009)
EnsemblASIC4 - 2q35 [CytoView hg19]  ASIC4 - 2q35 [CytoView hg38]
Mapping of homologs : NCBIASIC4 [Mapview hg19]  ASIC4 [Mapview hg38]
OMIM606715   
Gene and transcription
Genbank (Entrez)AK308804 AK309373 BC010439 BC031812 BC073912
RefSeq transcript (Entrez)NM_018674 NM_182847
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASIC4
Cluster EST : UnigeneHs.87469 [ NCBI ]
CGAP (NCI)Hs.87469
Alternative Splicing GalleryENSG00000072182
Gene ExpressionASIC4 [ NCBI-GEO ]   ASIC4 [ EBI - ARRAY_EXPRESS ]   ASIC4 [ SEEK ]   ASIC4 [ MEM ]
Gene Expression Viewer (FireBrowse)ASIC4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55515
GTEX Portal (Tissue expression)ASIC4
Human Protein AtlasENSG00000072182-ASIC4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96FT7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96FT7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96FT7
Splice isoforms : SwissVarQ96FT7
PhosPhoSitePlusQ96FT7
Domaine pattern : Prosite (Expaxy)ASC (PS01206)   
Domains : Interpro (EBI)Na+channel_ASC    Na+channel_ASC_CS   
Domain families : Pfam (Sanger)ASC (PF00858)   
Domain families : Pfam (NCBI)pfam00858   
Conserved Domain (NCBI)ASIC4
DMDM Disease mutations55515
Blocks (Seattle)ASIC4
SuperfamilyQ96FT7
Human Protein Atlas [tissue]ENSG00000072182-ASIC4 [tissue]
Peptide AtlasQ96FT7
HPRD16231
IPIIPI00183230   IPI00640354   IPI00062210   
Protein Interaction databases
DIP (DOE-UCLA)Q96FT7
IntAct (EBI)Q96FT7
FunCoupENSG00000072182
BioGRIDASIC4
STRING (EMBL)ASIC4
ZODIACASIC4
Ontologies - Pathways
QuickGOQ96FT7
Ontology : AmiGOion channel activity  sodium channel activity  integral component of plasma membrane  transport  sodium ion transmembrane transporter activity  sodium ion transmembrane transport  
Ontology : EGO-EBIion channel activity  sodium channel activity  integral component of plasma membrane  transport  sodium ion transmembrane transporter activity  sodium ion transmembrane transport  
NDEx NetworkASIC4
Atlas of Cancer Signalling NetworkASIC4
Wikipedia pathwaysASIC4
Orthology - Evolution
OrthoDB55515
GeneTree (enSembl)ENSG00000072182
Phylogenetic Trees/Animal Genes : TreeFamASIC4
HOVERGENQ96FT7
HOGENOMQ96FT7
Homologs : HomoloGeneASIC4
Homology/Alignments : Family Browser (UCSC)ASIC4
Gene fusions - Rearrangements
Tumor Fusion PortalASIC4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASIC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASIC4
dbVarASIC4
ClinVarASIC4
1000_GenomesASIC4 
Exome Variant ServerASIC4
ExAC (Exome Aggregation Consortium)ENSG00000072182
GNOMAD BrowserENSG00000072182
Genetic variants : HAPMAP55515
Genomic Variants (DGV)ASIC4 [DGVbeta]
DECIPHERASIC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASIC4 
Mutations
ICGC Data PortalASIC4 
TCGA Data PortalASIC4 
Broad Tumor PortalASIC4
OASIS PortalASIC4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDASIC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASIC4
DgiDB (Drug Gene Interaction Database)ASIC4
DoCM (Curated mutations)ASIC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASIC4 (select a term)
intoGenASIC4
Cancer3DASIC4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606715   
Orphanet
DisGeNETASIC4
MedgenASIC4
Genetic Testing Registry ASIC4
NextProtQ96FT7 [Medical]
TSGene55515
GENETestsASIC4
Target ValidationASIC4
Huge Navigator ASIC4 [HugePedia]
snp3D : Map Gene to Disease55515
BioCentury BCIQASIC4
ClinGenASIC4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55515
Chemical/Pharm GKB GenePA134956731
Clinical trialASIC4
Miscellaneous
canSAR (ICR)ASIC4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASIC4
EVEXASIC4
GoPubMedASIC4
iHOPASIC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:03:56 CET 2017

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