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ASMT (acetylserotonin O-methyltransferase)

Identity

Alias (NCBI)ASMTY
HIOMT
HIOMTY
HGNC (Hugo) ASMT
HGNC Alias symbHIOMT
ASMTY
HIOMTY
LocusID (NCBI) 438
Atlas_Id 51527
Location Xp22.33  [Link to chromosome band Xp22]
Location_base_pair Starts at 1595455 and ends at 1643081 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)ASMT   750
Cards
Entrez_Gene (NCBI)ASMT    acetylserotonin O-methyltransferase
AliasesASMTY; HIOMT; HIOMTY
GeneCards (Weizmann)ASMT
Ensembl hg19 (Hinxton)ENSG00000196433 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196433 [Gene_View]  ENSG00000196433 [Sequence]  chrX:1595455-1643081 [Contig_View]  ASMT [Vega]
ICGC DataPortalENSG00000196433
TCGA cBioPortalASMT
AceView (NCBI)ASMT
Genatlas (Paris)ASMT
SOURCE (Princeton)ASMT
Genetics Home Reference (NIH)ASMT
Genomic and cartography
GoldenPath hg38 (UCSC)ASMT  -     chrX:1595455-1643081 +  Xp22.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASMT  -     Xp22.33   [Description]    (hg19-Feb_2009)
GoldenPathASMT - Xp22.33 [CytoView hg19]  ASMT - Xp22.33 [CytoView hg38]
ImmunoBaseENSG00000196433
genome Data Viewer NCBIASMT [Mapview hg19]  
OMIM300015   402500   
Gene and transcription
Genbank (Entrez)AK314922 BC001620 KJ534774 KJ534775 KJ534776
RefSeq transcript (Entrez)NM_001171038 NM_001171039 NM_004043
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASMT
Alternative Splicing GalleryENSG00000196433
Gene ExpressionASMT [ NCBI-GEO ]   ASMT [ EBI - ARRAY_EXPRESS ]   ASMT [ SEEK ]   ASMT [ MEM ]
Gene Expression Viewer (FireBrowse)ASMT [ Firebrowse - Broad ]
GenevisibleExpression of ASMT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)438
GTEX Portal (Tissue expression)ASMT
Human Protein AtlasENSG00000196433-ASMT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46597   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46597  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46597
Splice isoforms : SwissVarP46597
Catalytic activity : Enzyme2.1.1.4 [ Enzyme-Expasy ]   2.1.1.42.1.1.4 [ IntEnz-EBI ]   2.1.1.4 [ BRENDA ]   2.1.1.4 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP46597
Domaine pattern : Prosite (Expaxy)SAM_OMT_II (PS51683)   
Domains : Interpro (EBI)ASMT_dimerisation    COMT-like    O_MeTrfase_dom    SAM-dependent_MTases    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Dimerisation2 (PF16864)    Methyltransf_2 (PF00891)   
Domain families : Pfam (NCBI)pfam16864    pfam00891   
Conserved Domain (NCBI)ASMT
Blocks (Seattle)ASMT
PDB (RSDB)4A6D    4A6E   
PDB Europe4A6D    4A6E   
PDB (PDBSum)4A6D    4A6E   
PDB (IMB)4A6D    4A6E   
Structural Biology KnowledgeBase4A6D    4A6E   
SCOP (Structural Classification of Proteins)4A6D    4A6E   
CATH (Classification of proteins structures)4A6D    4A6E   
SuperfamilyP46597
Human Protein Atlas [tissue]ENSG00000196433-ASMT [tissue]
Peptide AtlasP46597
HPRD02058
IPIIPI00007218   IPI00219431   IPI00219432   IPI00552424   
Protein Interaction databases
DIP (DOE-UCLA)P46597
IntAct (EBI)P46597
BioGRIDASMT
STRING (EMBL)ASMT
ZODIACASMT
Ontologies - Pathways
QuickGOP46597
Ontology : AmiGOcytosol  translation  O-methyltransferase activity  S-methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  acetylserotonin O-methyltransferase activity  acetylserotonin O-methyltransferase activity  aromatic compound biosynthetic process  melatonin biosynthetic process  melatonin biosynthetic process  melatonin biosynthetic process  methylation  identical protein binding  protein homodimerization activity  indolalkylamine biosynthetic process  
Ontology : EGO-EBIcytosol  translation  O-methyltransferase activity  S-methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  acetylserotonin O-methyltransferase activity  acetylserotonin O-methyltransferase activity  aromatic compound biosynthetic process  melatonin biosynthetic process  melatonin biosynthetic process  melatonin biosynthetic process  methylation  identical protein binding  protein homodimerization activity  indolalkylamine biosynthetic process  
Pathways : KEGGTryptophan metabolism   
NDEx NetworkASMT
Atlas of Cancer Signalling NetworkASMT
Wikipedia pathwaysASMT
Orthology - Evolution
OrthoDB438
GeneTree (enSembl)ENSG00000196433
Phylogenetic Trees/Animal Genes : TreeFamASMT
HOGENOMP46597
Homologs : HomoloGeneASMT
Homology/Alignments : Family Browser (UCSC)ASMT
Gene fusions - Rearrangements
Fusion : QuiverASMT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASMT [hg38]
dbVarASMT
ClinVarASMT
MonarchASMT
1000_GenomesASMT 
Exome Variant ServerASMT
GNOMAD BrowserENSG00000196433
Varsome BrowserASMT
Genomic Variants (DGV)ASMT [DGVbeta]
DECIPHERASMT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASMT 
Mutations
ICGC Data PortalASMT 
TCGA Data PortalASMT 
Broad Tumor PortalASMT
OASIS PortalASMT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASMT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DASMT
Mutations and Diseases : HGMDASMT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch ASMT
DgiDB (Drug Gene Interaction Database)ASMT
DoCM (Curated mutations)ASMT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASMT (select a term)
intoGenASMT
Cancer3DASMT(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300015    402500   
Orphanet
DisGeNETASMT
MedgenASMT
Genetic Testing Registry ASMT
NextProtP46597 [Medical]
GENETestsASMT
Target ValidationASMT
Huge Navigator ASMT [HugePedia]
ClinGenASMT
Clinical trials, drugs, therapy
MyCancerGenomeASMT
Protein Interactions : CTD
Pharm GKB GenePA25049
PharosP46597
Clinical trialASMT
Miscellaneous
canSAR (ICR)ASMT (select the gene name)
HarmonizomeASMT
DataMed IndexASMT
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXASMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:11:52 CET 2021

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