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ASPN (asporin)

Identity

Alias_namesasporin (LRR class 1)
Alias_symbol (synonym)FLJ20129
SLRR1C
PLAP1
Other aliasOS3
PLAP-1
HGNC (Hugo) ASPN
LocusID (NCBI) 54829
Atlas_Id 51344
Location 9q22.31  [Link to chromosome band 9q22]
Location_base_pair Starts at 92456207 and ends at 92482562 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ASPN   14872
Cards
Entrez_Gene (NCBI)ASPN  54829  asporin
AliasesOS3; PLAP-1; PLAP1; SLRR1C
GeneCards (Weizmann)ASPN
Ensembl hg19 (Hinxton)ENSG00000106819 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106819 [Gene_View]  chr9:92456207-92482562 [Contig_View]  ASPN [Vega]
ICGC DataPortalENSG00000106819
TCGA cBioPortalASPN
AceView (NCBI)ASPN
Genatlas (Paris)ASPN
WikiGenes54829
SOURCE (Princeton)ASPN
Genetics Home Reference (NIH)ASPN
Genomic and cartography
GoldenPath hg38 (UCSC)ASPN  -     chr9:92456207-92482562 -  9q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASPN  -     9q22.31   [Description]    (hg19-Feb_2009)
EnsemblASPN - 9q22.31 [CytoView hg19]  ASPN - 9q22.31 [CytoView hg38]
Mapping of homologs : NCBIASPN [Mapview hg19]  ASPN [Mapview hg38]
OMIM603932   607850   608135   
Gene and transcription
Genbank (Entrez)AF316824 AI741321 AK000136 AK027359 AK172737
RefSeq transcript (Entrez)NM_001193335 NM_017680
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASPN
Cluster EST : UnigeneHs.435655 [ NCBI ]
CGAP (NCI)Hs.435655
Alternative Splicing GalleryENSG00000106819
Gene ExpressionASPN [ NCBI-GEO ]   ASPN [ EBI - ARRAY_EXPRESS ]   ASPN [ SEEK ]   ASPN [ MEM ]
Gene Expression Viewer (FireBrowse)ASPN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54829
GTEX Portal (Tissue expression)ASPN
Human Protein AtlasENSG00000106819-ASPN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXN1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXN1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXN1
Splice isoforms : SwissVarQ9BXN1
PhosPhoSitePlusQ9BXN1
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Asporin    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT    SLRP_I_decor/aspor/byglycan   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)ASPN
DMDM Disease mutations54829
Blocks (Seattle)ASPN
SuperfamilyQ9BXN1
Human Protein Atlas [tissue]ENSG00000106819-ASPN [tissue]
Peptide AtlasQ9BXN1
HPRD16288
IPIIPI01011271   IPI00807405   IPI00418431   IPI00647693   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXN1
IntAct (EBI)Q9BXN1
FunCoupENSG00000106819
BioGRIDASPN
STRING (EMBL)ASPN
ZODIACASPN
Ontologies - Pathways
QuickGOQ9BXN1
Ontology : AmiGOprotein kinase inhibitor activity  calcium ion binding  collagen binding  proteinaceous extracellular matrix  cytoplasm  negative regulation of protein kinase activity  cytokine-mediated signaling pathway  bone mineralization  negative regulation of transforming growth factor beta receptor signaling pathway  extracellular matrix  negative regulation of JAK-STAT cascade  negative regulation of tooth mineralization  
Ontology : EGO-EBIprotein kinase inhibitor activity  calcium ion binding  collagen binding  proteinaceous extracellular matrix  cytoplasm  negative regulation of protein kinase activity  cytokine-mediated signaling pathway  bone mineralization  negative regulation of transforming growth factor beta receptor signaling pathway  extracellular matrix  negative regulation of JAK-STAT cascade  negative regulation of tooth mineralization  
NDEx NetworkASPN
Atlas of Cancer Signalling NetworkASPN
Wikipedia pathwaysASPN
Orthology - Evolution
OrthoDB54829
GeneTree (enSembl)ENSG00000106819
Phylogenetic Trees/Animal Genes : TreeFamASPN
HOVERGENQ9BXN1
HOGENOMQ9BXN1
Homologs : HomoloGeneASPN
Homology/Alignments : Family Browser (UCSC)ASPN
Gene fusions - Rearrangements
Tumor Fusion PortalASPN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASPN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASPN
dbVarASPN
ClinVarASPN
1000_GenomesASPN 
Exome Variant ServerASPN
ExAC (Exome Aggregation Consortium)ENSG00000106819
GNOMAD BrowserENSG00000106819
Genetic variants : HAPMAP54829
Genomic Variants (DGV)ASPN [DGVbeta]
DECIPHERASPN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASPN 
Mutations
ICGC Data PortalASPN 
TCGA Data PortalASPN 
Broad Tumor PortalASPN
OASIS PortalASPN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASPN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASPN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ASPN
DgiDB (Drug Gene Interaction Database)ASPN
DoCM (Curated mutations)ASPN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASPN (select a term)
intoGenASPN
Cancer3DASPN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603932    607850    608135   
Orphanet
DisGeNETASPN
MedgenASPN
Genetic Testing Registry ASPN
NextProtQ9BXN1 [Medical]
TSGene54829
GENETestsASPN
Target ValidationASPN
Huge Navigator ASPN [HugePedia]
snp3D : Map Gene to Disease54829
BioCentury BCIQASPN
ClinGenASPN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54829
Chemical/Pharm GKB GenePA25057
Clinical trialASPN
Miscellaneous
canSAR (ICR)ASPN (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASPN
EVEXASPN
GoPubMedASPN
iHOPASPN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:59 CET 2017

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