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ATAD2 (ATPase family, AAA domain containing 2)

Identity

Alias_symbol (synonym)PRO2000
DKFZp667N1320
MGC5254
MGC29843
CT137
Other aliasANCCA
HGNC (Hugo) ATAD2
LocusID (NCBI) 29028
Atlas_Id 50030
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 123319851 and ends at 123396465 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATAD2 (8q24.13) / ATAD2 (8q24.13)ATAD2 (8q24.13) / ERBB4 (2q34)ATAD2 (8q24.13) / FAM178B (2q11.2)
ATAD2 (8q24.13) / LRP12 (8q22.3)ATAD2 (8q24.13) / PODXL (7q32.3)ATAD2 (8q24.13) / RAD51B (14q24.1)
ATAD2 (8q24.13) / WDYHV1 (8q24.13)KMT2A (11q23.3) / ATAD2 (8q24.13)TPD52 (8q21.13) / ATAD2 (8q24.13)
ATAD2 8q24.13 / ERBB4 2q34ATAD2 8q24.13 / FAM178B 2q11.2ATAD2 8q24.13 / LRP12 8q22.3
ATAD2 8q24.13 / PODXL 7q32.3ATAD2 8q24.13 / RAD51B 14q24.1ATAD2 8q24.13 / WDYHV1 8q24.13
C8orf76 8q24.13 / ATAD2 8q24.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATAD2   30123
Cards
Entrez_Gene (NCBI)ATAD2  29028  ATPase family, AAA domain containing 2
AliasesANCCA; CT137; PRO2000
GeneCards (Weizmann)ATAD2
Ensembl hg19 (Hinxton)ENSG00000156802 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156802 [Gene_View]  chr8:123319851-123396465 [Contig_View]  ATAD2 [Vega]
ICGC DataPortalENSG00000156802
TCGA cBioPortalATAD2
AceView (NCBI)ATAD2
Genatlas (Paris)ATAD2
WikiGenes29028
SOURCE (Princeton)ATAD2
Genetics Home Reference (NIH)ATAD2
Genomic and cartography
GoldenPath hg38 (UCSC)ATAD2  -     chr8:123319851-123396465 -  8q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATAD2  -     8q24.13   [Description]    (hg19-Feb_2009)
EnsemblATAD2 - 8q24.13 [CytoView hg19]  ATAD2 - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBIATAD2 [Mapview hg19]  ATAD2 [Mapview hg38]
OMIM611941   
Gene and transcription
Genbank (Entrez)AF118088 AK097133 AL833653 AY598335 BC007123
RefSeq transcript (Entrez)NM_014109
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATAD2
Cluster EST : UnigeneHs.370834 [ NCBI ]
CGAP (NCI)Hs.370834
Alternative Splicing GalleryENSG00000156802
Gene ExpressionATAD2 [ NCBI-GEO ]   ATAD2 [ EBI - ARRAY_EXPRESS ]   ATAD2 [ SEEK ]   ATAD2 [ MEM ]
Gene Expression Viewer (FireBrowse)ATAD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29028
GTEX Portal (Tissue expression)ATAD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PL18   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PL18  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PL18
Splice isoforms : SwissVarQ6PL18
Catalytic activity : Enzyme3.6.1.3 [ Enzyme-Expasy ]   3.6.1.33.6.1.3 [ IntEnz-EBI ]   3.6.1.3 [ BRENDA ]   3.6.1.3 [ KEGG ]   
PhosPhoSitePlusQ6PL18
Domaine pattern : Prosite (Expaxy)AAA (PS00674)    BROMODOMAIN_2 (PS50014)   
Domains : Interpro (EBI)AAA+_ATPase    ANCCA    ARM-like    ATPase_AAA_core    ATPase_AAA_CS    Bromodomain    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA (PF00004)    Bromodomain (PF00439)   
Domain families : Pfam (NCBI)pfam00004    pfam00439   
Domain families : Smart (EMBL)AAA (SM00382)  BROMO (SM00297)  
Conserved Domain (NCBI)ATAD2
DMDM Disease mutations29028
Blocks (Seattle)ATAD2
PDB (SRS)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
PDB (PDBSum)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
PDB (IMB)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
PDB (RSDB)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
Structural Biology KnowledgeBase3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
SCOP (Structural Classification of Proteins)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
CATH (Classification of proteins structures)3DAI    4QSP    4QSQ    4QSR    4QSS    4QST    4QSU    4QSV    4QSW    4QSX    4QUT    4QUU    4TT2    4TT4    4TT6    4TTE    4TU4    4TU6    4TYL    4TZ2    4TZ8    5A5N    5A5O    5A5P    5A5Q    5A5R    5A81    5A82    5A83    5EPB    5F36    5F3A    5LJ0   
SuperfamilyQ6PL18
Human Protein AtlasENSG00000156802
Peptide AtlasQ6PL18
HPRD10678
IPIIPI00170548   IPI00470801   IPI00974250   IPI00984296   IPI00974295   
Protein Interaction databases
DIP (DOE-UCLA)Q6PL18
IntAct (EBI)Q6PL18
FunCoupENSG00000156802
BioGRIDATAD2
STRING (EMBL)ATAD2
ZODIACATAD2
Ontologies - Pathways
QuickGOQ6PL18
Ontology : AmiGOchromatin binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  chromatin organization  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  ATPase activity  negative regulation of chromatin silencing  histone binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  
Ontology : EGO-EBIchromatin binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  chromatin organization  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  ATPase activity  negative regulation of chromatin silencing  histone binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  
NDEx NetworkATAD2
Atlas of Cancer Signalling NetworkATAD2
Wikipedia pathwaysATAD2
Orthology - Evolution
OrthoDB29028
GeneTree (enSembl)ENSG00000156802
Phylogenetic Trees/Animal Genes : TreeFamATAD2
HOVERGENQ6PL18
HOGENOMQ6PL18
Homologs : HomoloGeneATAD2
Homology/Alignments : Family Browser (UCSC)ATAD2
Gene fusions - Rearrangements
Fusion : MitelmanATAD2/ERBB4 [8q24.13/2q34]  
Fusion : MitelmanATAD2/FAM178B [8q24.13/2q11.2]  [t(2;8)(q11;q24)]  
Fusion : MitelmanATAD2/LRP12 [8q24.13/8q22.3]  [t(8;8)(q22;q24)]  
Fusion : MitelmanATAD2/PODXL [8q24.13/7q32.3]  [t(7;8)(q32;q24)]  
Fusion : MitelmanATAD2/RAD51B [8q24.13/14q24.1]  [t(8;14)(q24;q24)]  
Fusion : MitelmanATAD2/WDYHV1 [8q24.13/8q24.13]  [t(8;8)(q24;q24)]  
Fusion : MitelmanKMT2A/ATAD2 [11q23.3/8q24.13]  [t(8;8)(q24;q24)]  
Fusion: TCGAATAD2 8q24.13 ERBB4 2q34 HNSC
Fusion: TCGAATAD2 8q24.13 FAM178B 2q11.2 BRCA
Fusion: TCGAATAD2 8q24.13 LRP12 8q22.3 LUAD
Fusion: TCGAATAD2 8q24.13 PODXL 7q32.3 BRCA
Fusion: TCGAATAD2 8q24.13 RAD51B 14q24.1 BRCA
Fusion: TCGAATAD2 8q24.13 WDYHV1 8q24.13 LUAD
Fusion: TCGAC8orf76 8q24.13 ATAD2 8q24.13 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATAD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATAD2
dbVarATAD2
ClinVarATAD2
1000_GenomesATAD2 
Exome Variant ServerATAD2
ExAC (Exome Aggregation Consortium)ATAD2 (select the gene name)
Genetic variants : HAPMAP29028
Genomic Variants (DGV)ATAD2 [DGVbeta]
DECIPHERATAD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATAD2 
Mutations
ICGC Data PortalATAD2 
TCGA Data PortalATAD2 
Broad Tumor PortalATAD2
OASIS PortalATAD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATAD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATAD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATAD2
DgiDB (Drug Gene Interaction Database)ATAD2
DoCM (Curated mutations)ATAD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATAD2 (select a term)
intoGenATAD2
Cancer3DATAD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611941   
Orphanet
MedgenATAD2
Genetic Testing Registry ATAD2
NextProtQ6PL18 [Medical]
TSGene29028
GENETestsATAD2
Huge Navigator ATAD2 [HugePedia]
snp3D : Map Gene to Disease29028
BioCentury BCIQATAD2
ClinGenATAD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29028
Chemical/Pharm GKB GenePA134895566
Clinical trialATAD2
Miscellaneous
canSAR (ICR)ATAD2 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATAD2
EVEXATAD2
GoPubMedATAD2
iHOPATAD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:06:58 CEST 2017

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