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ATAD2B (ATPase family, AAA domain containing 2B)

Identity

Alias_symbol (synonym)KIAA1240
Other alias-
HGNC (Hugo) ATAD2B
LocusID (NCBI) 54454
Atlas_Id 52277
Location 2p24.1  [Link to chromosome band 2p24]
Location_base_pair Starts at 23971534 and ends at 24149984 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATAD2B (2p24.1) / AC008073.5 ()ATAD2B (2p24.1) / ATG2B (14q32.2)ATAD2B (2p24.1) / ITSN2 (2p23.3)
ATAD2B (2p24.1) / XKR4 (8q12.1)ATAD2B 2p24.1 AC008073.5ATAD2B 2p24.1 / ITSN2 2p23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATAD2B   29230
Cards
Entrez_Gene (NCBI)ATAD2B  54454  ATPase family, AAA domain containing 2B
Aliases
GeneCards (Weizmann)ATAD2B
Ensembl hg19 (Hinxton)ENSG00000119778 [Gene_View]  chr2:23971534-24149984 [Contig_View]  ATAD2B [Vega]
Ensembl hg38 (Hinxton)ENSG00000119778 [Gene_View]  chr2:23971534-24149984 [Contig_View]  ATAD2B [Vega]
ICGC DataPortalENSG00000119778
TCGA cBioPortalATAD2B
AceView (NCBI)ATAD2B
Genatlas (Paris)ATAD2B
WikiGenes54454
SOURCE (Princeton)ATAD2B
Genetics Home Reference (NIH)ATAD2B
Genomic and cartography
GoldenPath hg19 (UCSC)ATAD2B  -     chr2:23971534-24149984 -  2p24.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ATAD2B  -     2p24.1   [Description]    (hg38-Dec_2013)
EnsemblATAD2B - 2p24.1 [CytoView hg19]  ATAD2B - 2p24.1 [CytoView hg38]
Mapping of homologs : NCBIATAD2B [Mapview hg19]  ATAD2B [Mapview hg38]
OMIM615347   
Gene and transcription
Genbank (Entrez)AA767863 AB033066 AF038204 AK023705 AK094821
RefSeq transcript (Entrez)NM_001242338 NM_017552
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_029017 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)ATAD2B
Cluster EST : UnigeneHs.467862 [ NCBI ]
CGAP (NCI)Hs.467862
Alternative Splicing GalleryENSG00000119778
Gene ExpressionATAD2B [ NCBI-GEO ]   ATAD2B [ EBI - ARRAY_EXPRESS ]   ATAD2B [ SEEK ]   ATAD2B [ MEM ]
Gene Expression Viewer (FireBrowse)ATAD2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54454
GTEX Portal (Tissue expression)ATAD2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULI0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULI0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULI0
Splice isoforms : SwissVarQ9ULI0
PhosPhoSitePlusQ9ULI0
Domaine pattern : Prosite (Expaxy)AAA (PS00674)    BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)   
Domains : Interpro (EBI)AAA+_ATPase    ATPase_AAA_core    ATPase_AAA_CS    Bromodomain    Bromodomain_CS    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA (PF00004)    Bromodomain (PF00439)   
Domain families : Pfam (NCBI)pfam00004    pfam00439   
Domain families : Smart (EMBL)AAA (SM00382)  BROMO (SM00297)  
Conserved Domain (NCBI)ATAD2B
DMDM Disease mutations54454
Blocks (Seattle)ATAD2B
PDB (SRS)2DKW    3LXJ   
PDB (PDBSum)2DKW    3LXJ   
PDB (IMB)2DKW    3LXJ   
PDB (RSDB)2DKW    3LXJ   
Structural Biology KnowledgeBase2DKW    3LXJ   
SCOP (Structural Classification of Proteins)2DKW    3LXJ   
CATH (Classification of proteins structures)2DKW    3LXJ   
SuperfamilyQ9ULI0
Human Protein AtlasENSG00000119778
Peptide AtlasQ9ULI0
IPIIPI00739581   IPI00456004   IPI01012544   IPI00953211   IPI00893906   IPI00894064   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULI0
IntAct (EBI)Q9ULI0
FunCoupENSG00000119778
BioGRIDATAD2B
STRING (EMBL)ATAD2B
ZODIACATAD2B
Ontologies - Pathways
QuickGOQ9ULI0
Ontology : AmiGOchromatin binding  ATP binding  nucleus  ATPase activity  negative regulation of chromatin silencing  positive regulation of transcription from RNA polymerase II promoter  lysine-acetylated histone binding  
Ontology : EGO-EBIchromatin binding  ATP binding  nucleus  ATPase activity  negative regulation of chromatin silencing  positive regulation of transcription from RNA polymerase II promoter  lysine-acetylated histone binding  
NDEx NetworkATAD2B
Atlas of Cancer Signalling NetworkATAD2B
Wikipedia pathwaysATAD2B
Orthology - Evolution
OrthoDB54454
GeneTree (enSembl)ENSG00000119778
Phylogenetic Trees/Animal Genes : TreeFamATAD2B
HOVERGENQ9ULI0
HOGENOMQ9ULI0
Homologs : HomoloGeneATAD2B
Homology/Alignments : Family Browser (UCSC)ATAD2B
Gene fusions - Rearrangements
Fusion : MitelmanATAD2B/ITSN2 [2p24.1/2p23.3]  
Fusion: TCGAATAD2B 2p24.1 AC008073.5 LGG
Fusion: TCGAATAD2B 2p24.1 ITSN2 2p23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATAD2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATAD2B
dbVarATAD2B
ClinVarATAD2B
1000_GenomesATAD2B 
Exome Variant ServerATAD2B
ExAC (Exome Aggregation Consortium)ATAD2B (select the gene name)
Genetic variants : HAPMAP54454
Genomic Variants (DGV)ATAD2B [DGVbeta]
DECIPHER (Syndromes)2:23971534-24149984  ENSG00000119778
CONAN: Copy Number AnalysisATAD2B 
Mutations
ICGC Data PortalATAD2B 
TCGA Data PortalATAD2B 
Broad Tumor PortalATAD2B
OASIS PortalATAD2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATAD2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATAD2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATAD2B
DgiDB (Drug Gene Interaction Database)ATAD2B
DoCM (Curated mutations)ATAD2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATAD2B (select a term)
intoGenATAD2B
Cancer3DATAD2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615347   
Orphanet
MedgenATAD2B
Genetic Testing Registry ATAD2B
NextProtQ9ULI0 [Medical]
TSGene54454
GENETestsATAD2B
Huge Navigator ATAD2B [HugePedia]
snp3D : Map Gene to Disease54454
BioCentury BCIQATAD2B
ClinGenATAD2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54454
Chemical/Pharm GKB GenePA162377039
Clinical trialATAD2B
Miscellaneous
canSAR (ICR)ATAD2B (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATAD2B
EVEXATAD2B
GoPubMedATAD2B
iHOPATAD2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:56:47 CET 2017

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