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ATAD2B (ATPase family AAA domain containing 2B)

Identity

Alias (NCBI)-
HGNC (Hugo) ATAD2B
HGNC Alias symbKIAA1240
LocusID (NCBI) 54454
Atlas_Id 52277
Location 2p24.1  [Link to chromosome band 2p24]
Location_base_pair Starts at 23748664 and ends at 23927123 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATAD2B (2p24.1) / AC008073.5 ()ATAD2B (2p24.1) / ATG2B (14q32.2)ATAD2B (2p24.1) / ITSN2 (2p23.3)
ATAD2B (2p24.1) / XKR4 (8q12.1)ATAD2B 2p24.1 AC008073.5ATAD2B 2p24.1 / ITSN2 2p23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  ATAD2B/ITSN2 (2p23)


External links

Nomenclature
HGNC (Hugo)ATAD2B   29230
Cards
Entrez_Gene (NCBI)ATAD2B    ATPase family AAA domain containing 2B
Aliases
GeneCards (Weizmann)ATAD2B
Ensembl hg19 (Hinxton)ENSG00000119778 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119778 [Gene_View]  ENSG00000119778 [Sequence]  chr2:23748664-23927123 [Contig_View]  ATAD2B [Vega]
ICGC DataPortalENSG00000119778
TCGA cBioPortalATAD2B
AceView (NCBI)ATAD2B
Genatlas (Paris)ATAD2B
SOURCE (Princeton)ATAD2B
Genetics Home Reference (NIH)ATAD2B
Genomic and cartography
GoldenPath hg38 (UCSC)ATAD2B  -     chr2:23748664-23927123 -  2p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATAD2B  -     2p24.1   [Description]    (hg19-Feb_2009)
GoldenPathATAD2B - 2p24.1 [CytoView hg19]  ATAD2B - 2p24.1 [CytoView hg38]
ImmunoBaseENSG00000119778
genome Data Viewer NCBIATAD2B [Mapview hg19]  
OMIM615347   
Gene and transcription
Genbank (Entrez)AA767863 AB033066 AF038204 AK023705 AK027272
RefSeq transcript (Entrez)NM_001242338 NM_001354107 NM_017552
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATAD2B
Alternative Splicing GalleryENSG00000119778
Gene ExpressionATAD2B [ NCBI-GEO ]   ATAD2B [ EBI - ARRAY_EXPRESS ]   ATAD2B [ SEEK ]   ATAD2B [ MEM ]
Gene Expression Viewer (FireBrowse)ATAD2B [ Firebrowse - Broad ]
GenevisibleExpression of ATAD2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54454
GTEX Portal (Tissue expression)ATAD2B
Human Protein AtlasENSG00000119778-ATAD2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULI0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULI0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULI0
Splice isoforms : SwissVarQ9ULI0
PhosPhoSitePlusQ9ULI0
Domaine pattern : Prosite (Expaxy)AAA (PS00674)    BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)   
Domains : Interpro (EBI)AAA+_ATPase    AAA_lid_3    ATPase_AAA_core    ATPase_AAA_CS    Bromodomain    Bromodomain-like_sf    Bromodomain_CS    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA (PF00004)    AAA_lid_3 (PF17862)    Bromodomain (PF00439)   
Domain families : Pfam (NCBI)pfam00004    pfam17862    pfam00439   
Domain families : Smart (EMBL)AAA (SM00382)  BROMO (SM00297)  
Conserved Domain (NCBI)ATAD2B
Blocks (Seattle)ATAD2B
PDB (RSDB)2DKW    3LXJ   
PDB Europe2DKW    3LXJ   
PDB (PDBSum)2DKW    3LXJ   
PDB (IMB)2DKW    3LXJ   
Structural Biology KnowledgeBase2DKW    3LXJ   
SCOP (Structural Classification of Proteins)2DKW    3LXJ   
CATH (Classification of proteins structures)2DKW    3LXJ   
SuperfamilyQ9ULI0
Human Protein Atlas [tissue]ENSG00000119778-ATAD2B [tissue]
Peptide AtlasQ9ULI0
IPIIPI00739581   IPI00456004   IPI01012544   IPI00953211   IPI00893906   IPI00894064   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULI0
IntAct (EBI)Q9ULI0
BioGRIDATAD2B
STRING (EMBL)ATAD2B
ZODIACATAD2B
Ontologies - Pathways
QuickGOQ9ULI0
Ontology : AmiGOchromatin binding  ATP binding  nucleus  nucleus  nucleoplasm  ATPase activity  negative regulation of chromatin silencing  histone binding  positive regulation of transcription by RNA polymerase II  lysine-acetylated histone binding  
Ontology : EGO-EBIchromatin binding  ATP binding  nucleus  nucleus  nucleoplasm  ATPase activity  negative regulation of chromatin silencing  histone binding  positive regulation of transcription by RNA polymerase II  lysine-acetylated histone binding  
NDEx NetworkATAD2B
Atlas of Cancer Signalling NetworkATAD2B
Wikipedia pathwaysATAD2B
Orthology - Evolution
OrthoDB54454
GeneTree (enSembl)ENSG00000119778
Phylogenetic Trees/Animal Genes : TreeFamATAD2B
HOGENOMQ9ULI0
Homologs : HomoloGeneATAD2B
Homology/Alignments : Family Browser (UCSC)ATAD2B
Gene fusions - Rearrangements
Fusion : MitelmanATAD2B/ITSN2 [2p24.1/2p23.3]  
Fusion PortalATAD2B 2p24.1 AC008073.5 LGG
Fusion PortalATAD2B 2p24.1 ITSN2 2p23.3 BRCA
Fusion : QuiverATAD2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATAD2B [hg38]
dbVarATAD2B
ClinVarATAD2B
MonarchATAD2B
1000_GenomesATAD2B 
Exome Variant ServerATAD2B
GNOMAD BrowserENSG00000119778
Varsome BrowserATAD2B
Genomic Variants (DGV)ATAD2B [DGVbeta]
DECIPHERATAD2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATAD2B 
Mutations
ICGC Data PortalATAD2B 
TCGA Data PortalATAD2B 
Broad Tumor PortalATAD2B
OASIS PortalATAD2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATAD2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DATAD2B
Mutations and Diseases : HGMDATAD2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATAD2B
DgiDB (Drug Gene Interaction Database)ATAD2B
DoCM (Curated mutations)ATAD2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATAD2B (select a term)
intoGenATAD2B
Cancer3DATAD2B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615347   
Orphanet
DisGeNETATAD2B
MedgenATAD2B
Genetic Testing Registry ATAD2B
NextProtQ9ULI0 [Medical]
GENETestsATAD2B
Target ValidationATAD2B
Huge Navigator ATAD2B [HugePedia]
ClinGenATAD2B
Clinical trials, drugs, therapy
MyCancerGenomeATAD2B
Protein Interactions : CTD
Pharm GKB GenePA162377039
PharosQ9ULI0
Clinical trialATAD2B
Miscellaneous
canSAR (ICR)ATAD2B (select the gene name)
HarmonizomeATAD2B
DataMed IndexATAD2B
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXATAD2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:06:24 CET 2021

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