Identity
HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
AAA-TOB3,TOB3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83858
MIM: 612317
HGNC: 24007
Ensembl: ENSG00000160072
Variants:
dbSNP: 83858
ClinVar: 83858
TCGA: ENSG00000160072
COSMIC: ATAD3B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160072 | ENST00000308647 | Q5T9A4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37286092 | 2023 | Circ_ATAD3B inhibits cell proliferation of breast cancer via mediating the miR-570-3p/MX2 axis. | 2 |
| 37286092 | 2023 | Circ_ATAD3B inhibits cell proliferation of breast cancer via mediating the miR-570-3p/MX2 axis. | 2 |
| 35136033 | 2022 | ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study. | 6 |
| 35136033 | 2022 | ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study. | 6 |
| 33665835 | 2021 | ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA. | 34 |
| 33665835 | 2021 | ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA. | 34 |
| 28549128 | 2017 | ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism. | 60 |
| 28623644 | 2017 | Increased AAA-TOB3 correlates with lymph node metastasis and advanced stage of lung adenocarcinoma. | 2 |
| 28549128 | 2017 | ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism. | 60 |
| 28623644 | 2017 | Increased AAA-TOB3 correlates with lymph node metastasis and advanced stage of lung adenocarcinoma. | 2 |
| 24239551 | 2014 | Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues. | 11 |
| 24239551 | 2014 | Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues. | 11 |
| 23818839 | 2013 | Integrative analysis of deep sequencing data identifies estrogen receptor early response genes and links ATAD3B to poor survival in breast cancer. | 6 |
| 23818839 | 2013 | Integrative analysis of deep sequencing data identifies estrogen receptor early response genes and links ATAD3B to poor survival in breast cancer. | 6 |
| 22664726 | 2012 | ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A. | 21 |
Citation
Dessen P
ATAD3B (ATPase family AAA domain containing 3B)
Atlas Genet Cytogenet Oncol Haematol. 2012-03-01
Online version: http://atlasgeneticsoncology.org/gene/52623/atad3b
