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ATE1 (arginyltransferase 1)

Identity

Other alias-
HGNC (Hugo) ATE1
LocusID (NCBI) 11101
Atlas_Id 57224
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 121740421 and ends at 121928063 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATE1 (10q26.13) / ZRANB1 (10q26.13)FGFR2 (10q26.13) / ATE1 (10q26.13)MTSS1 (8q24.13) / ATE1 (10q26.13)
PVT1 (8q24.21) / ATE1 (10q26.13)SLTM (15q22.1) / ATE1 (10q26.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(8;10)(q24;q26) PVT1/ATE1
ATE1/ZRANB1 (10q26)
t(10;15)(q26;q22) SLTM/ATE1

External links

Nomenclature
HGNC (Hugo)ATE1   782
Cards
Entrez_Gene (NCBI)ATE1  11101  arginyltransferase 1
Aliases
GeneCards (Weizmann)ATE1
Ensembl hg19 (Hinxton)ENSG00000107669 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107669 [Gene_View]  ENSG00000107669 [Sequence]  chr10:121740421-121928063 [Contig_View]  ATE1 [Vega]
ICGC DataPortalENSG00000107669
TCGA cBioPortalATE1
AceView (NCBI)ATE1
Genatlas (Paris)ATE1
WikiGenes11101
SOURCE (Princeton)ATE1
Genetics Home Reference (NIH)ATE1
Genomic and cartography
GoldenPath hg38 (UCSC)ATE1  -     chr10:121740421-121928063 -  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATE1  -     10q26.13   [Description]    (hg19-Feb_2009)
EnsemblATE1 - 10q26.13 [CytoView hg19]  ATE1 - 10q26.13 [CytoView hg38]
Mapping of homologs : NCBIATE1 [Mapview hg19]  ATE1 [Mapview hg38]
OMIM607103   
Gene and transcription
Genbank (Entrez)AF079098 AF079099 AK124669 AK292657 AK295642
RefSeq transcript (Entrez)NM_001001976 NM_001288734 NM_001288735 NM_001288736 NM_007041
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATE1
Cluster EST : UnigeneHs.632080 [ NCBI ]
CGAP (NCI)Hs.632080
Alternative Splicing GalleryENSG00000107669
Gene ExpressionATE1 [ NCBI-GEO ]   ATE1 [ EBI - ARRAY_EXPRESS ]   ATE1 [ SEEK ]   ATE1 [ MEM ]
Gene Expression Viewer (FireBrowse)ATE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11101
GTEX Portal (Tissue expression)ATE1
Human Protein AtlasENSG00000107669-ATE1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95260   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95260  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95260
Splice isoforms : SwissVarO95260
Catalytic activity : Enzyme2.3.2.8 [ Enzyme-Expasy ]   2.3.2.82.3.2.8 [ IntEnz-EBI ]   2.3.2.8 [ BRENDA ]   2.3.2.8 [ KEGG ]   
PhosPhoSitePlusO95260
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    Arg-tRNA-P_Trfase_1_euk    N-end_Aminoacyl_Trfase    N-end_Aminoacyl_Trfase_C    N-end_Aminoacyl_Trfase_N   
Domain families : Pfam (Sanger)ATE_C (PF04377)    ATE_N (PF04376)   
Domain families : Pfam (NCBI)pfam04377    pfam04376   
Conserved Domain (NCBI)ATE1
DMDM Disease mutations11101
Blocks (Seattle)ATE1
SuperfamilyO95260
Human Protein Atlas [tissue]ENSG00000107669-ATE1 [tissue]
Peptide AtlasO95260
IPIIPI00029472   IPI00218377   IPI01012837   IPI00982840   IPI00513865   IPI01013967   
Protein Interaction databases
DIP (DOE-UCLA)O95260
IntAct (EBI)O95260
FunCoupENSG00000107669
BioGRIDATE1
STRING (EMBL)ATE1
ZODIACATE1
Ontologies - Pathways
QuickGOO95260
Ontology : AmiGOarginyltransferase activity  arginyltransferase activity  protein binding  nucleus  cytoplasm  cytoplasm  proteasomal protein catabolic process  protein arginylation  protein arginylation  
Ontology : EGO-EBIarginyltransferase activity  arginyltransferase activity  protein binding  nucleus  cytoplasm  cytoplasm  proteasomal protein catabolic process  protein arginylation  protein arginylation  
NDEx NetworkATE1
Atlas of Cancer Signalling NetworkATE1
Wikipedia pathwaysATE1
Orthology - Evolution
OrthoDB11101
GeneTree (enSembl)ENSG00000107669
Phylogenetic Trees/Animal Genes : TreeFamATE1
HOVERGENO95260
HOGENOMO95260
Homologs : HomoloGeneATE1
Homology/Alignments : Family Browser (UCSC)ATE1
Gene fusions - Rearrangements
Fusion : QuiverATE1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATE1
dbVarATE1
ClinVarATE1
1000_GenomesATE1 
Exome Variant ServerATE1
ExAC (Exome Aggregation Consortium)ENSG00000107669
GNOMAD BrowserENSG00000107669
Varsome BrowserATE1
Genetic variants : HAPMAP11101
Genomic Variants (DGV)ATE1 [DGVbeta]
DECIPHERATE1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATE1 
Mutations
ICGC Data PortalATE1 
TCGA Data PortalATE1 
Broad Tumor PortalATE1
OASIS PortalATE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATE1
BioMutasearch ATE1
DgiDB (Drug Gene Interaction Database)ATE1
DoCM (Curated mutations)ATE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATE1 (select a term)
intoGenATE1
Cancer3DATE1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607103   
Orphanet
DisGeNETATE1
MedgenATE1
Genetic Testing Registry ATE1
NextProtO95260 [Medical]
TSGene11101
GENETestsATE1
Target ValidationATE1
Huge Navigator ATE1 [HugePedia]
snp3D : Map Gene to Disease11101
BioCentury BCIQATE1
ClinGenATE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11101
Chemical/Pharm GKB GenePA25082
Clinical trialATE1
Miscellaneous
canSAR (ICR)ATE1 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATE1
EVEXATE1
GoPubMedATE1
iHOPATE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 10:52:46 CET 2018
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