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ATF7 (activating transcription factor 7)

Identity

Alias_symbol (synonym)ATFA
Other alias
HGNC (Hugo) ATF7
LocusID (NCBI) 11016
Atlas_Id 50476
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53512059 and ends at 53626415 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATF7 (12q13.13) / ATP5G2 (12q13.13)ATF7 (12q13.13) / SPATS2 (12q13.12)GGA3 (17q25.1) / ATF7 (12q13.13)
NELL2 (12q12) / ATF7 (12q13.13)RNMT (18p11.21) / ATF7 (12q13.13)SLC29A3 (10q22.1) / ATF7 (12q13.13)
STK24 (13q32.2) / ATF7 (12q13.13)ATF7 12q13.13 / ATP5G2 12q13.13ATF7 12q13.13 / SPATS2 12q13.12
GGA3 17q25.1 / ATF7 12q13.13NELL2 12q12 / ATF7 12q13.13STK24 13q32.2 / ATF7 12q13.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(12;12)(q12;q13) NELL2/ATF7
ATF7/SPATS2 (12q13)
t(12;13)(q13;q32) STK24/ATF7
t(12;17)(q13;q25) GGA3/ATF7


External links

Nomenclature
HGNC (Hugo)ATF7   792
Cards
Entrez_Gene (NCBI)ATF7  11016  activating transcription factor 7
AliasesATFA
GeneCards (Weizmann)ATF7
Ensembl hg19 (Hinxton)ENSG00000170653 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170653 [Gene_View]  ENSG00000170653 [Sequence]  chr12:53512059-53626415 [Contig_View]  ATF7 [Vega]
ICGC DataPortalENSG00000170653
TCGA cBioPortalATF7
AceView (NCBI)ATF7
Genatlas (Paris)ATF7
WikiGenes11016
SOURCE (Princeton)ATF7
Genetics Home Reference (NIH)ATF7
Genomic and cartography
GoldenPath hg38 (UCSC)ATF7  -     chr12:53512059-53626415 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATF7  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblATF7 - 12q13.13 [CytoView hg19]  ATF7 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIATF7 [Mapview hg19]  ATF7 [Mapview hg38]
OMIM606371   
Gene and transcription
Genbank (Entrez)AA679547 AK298853 AK302907 AK310355 AK313507
RefSeq transcript (Entrez)NM_001130059 NM_001130060 NM_001206682 NM_001206683 NM_001366555 NM_001366556 NM_001366558 NM_001366559 NM_001366560 NM_001366561 NM_001366562 NM_001366563 NM_006856
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATF7
Cluster EST : UnigeneHs.633602 [ NCBI ]
CGAP (NCI)Hs.633602
Alternative Splicing GalleryENSG00000170653
Gene ExpressionATF7 [ NCBI-GEO ]   ATF7 [ EBI - ARRAY_EXPRESS ]   ATF7 [ SEEK ]   ATF7 [ MEM ]
Gene Expression Viewer (FireBrowse)ATF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11016
GTEX Portal (Tissue expression)ATF7
Human Protein AtlasENSG00000170653-ATF7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17544   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17544  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17544
Splice isoforms : SwissVarP17544
PhosPhoSitePlusP17544
Domaine pattern : Prosite (Expaxy)BZIP (PS50217)    BZIP_BASIC (PS00036)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)bZIP    TF_CRE-BP1-typ    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)bZIP_1 (PF00170)   
Domain families : Pfam (NCBI)pfam00170   
Domain families : Smart (EMBL)BRLZ (SM00338)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ATF7
DMDM Disease mutations11016
Blocks (Seattle)ATF7
SuperfamilyP17544
Human Protein Atlas [tissue]ENSG00000170653-ATF7 [tissue]
Peptide AtlasP17544
HPRD06968
IPIIPI00015147   IPI00909393   IPI00218344   IPI00009975   IPI00641268   IPI01022023   IPI00744535   
Protein Interaction databases
DIP (DOE-UCLA)P17544
IntAct (EBI)P17544
FunCoupENSG00000170653
BioGRIDATF7
STRING (EMBL)ATF7
ZODIACATF7
Ontologies - Pathways
QuickGOP17544
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription factor binding  viral process  enzyme binding  nuclear periphery  metal ion binding  mitogen-activated protein kinase binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription factor binding  viral process  enzyme binding  nuclear periphery  metal ion binding  mitogen-activated protein kinase binding  
NDEx NetworkATF7
Atlas of Cancer Signalling NetworkATF7
Wikipedia pathwaysATF7
Orthology - Evolution
OrthoDB11016
GeneTree (enSembl)ENSG00000170653
Phylogenetic Trees/Animal Genes : TreeFamATF7
HOVERGENP17544
HOGENOMP17544
Homologs : HomoloGeneATF7
Homology/Alignments : Family Browser (UCSC)ATF7
Gene fusions - Rearrangements
Fusion : MitelmanATF7/ATP5G2 [12q13.13/12q13.13]  
Fusion : MitelmanATF7/SPATS2 [12q13.13/12q13.12]  [t(12;12)(q13;q13)]  
Fusion : MitelmanGGA3/ATF7 [17q25.1/12q13.13]  [t(12;17)(q13;q25)]  
Fusion : MitelmanNELL2/ATF7 [12q12/12q13.13]  [t(12;12)(q12;q13)]  
Fusion : MitelmanSTK24/ATF7 [13q32.2/12q13.13]  [t(12;13)(q13;q32)]  
Fusion PortalATF7 12q13.13 ATP5G2 12q13.13 BRCA HNSC
Fusion PortalATF7 12q13.13 SPATS2 12q13.12 BRCA
Fusion PortalGGA3 17q25.1 ATF7 12q13.13 BRCA
Fusion PortalNELL2 12q12 ATF7 12q13.13 BRCA
Fusion PortalSTK24 13q32.2 ATF7 12q13.13 BRCA
Fusion : QuiverATF7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATF7
dbVarATF7
ClinVarATF7
1000_GenomesATF7 
Exome Variant ServerATF7
ExAC (Exome Aggregation Consortium)ENSG00000170653
GNOMAD BrowserENSG00000170653
Varsome BrowserATF7
Genetic variants : HAPMAP11016
Genomic Variants (DGV)ATF7 [DGVbeta]
DECIPHERATF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATF7 
Mutations
ICGC Data PortalATF7 
TCGA Data PortalATF7 
Broad Tumor PortalATF7
OASIS PortalATF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATF7
DgiDB (Drug Gene Interaction Database)ATF7
DoCM (Curated mutations)ATF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATF7 (select a term)
intoGenATF7
Cancer3DATF7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606371   
Orphanet
DisGeNETATF7
MedgenATF7
Genetic Testing Registry ATF7
NextProtP17544 [Medical]
TSGene11016
GENETestsATF7
Target ValidationATF7
Huge Navigator ATF7 [HugePedia]
snp3D : Map Gene to Disease11016
BioCentury BCIQATF7
ClinGenATF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11016
Chemical/Pharm GKB GenePA25092
Clinical trialATF7
Miscellaneous
canSAR (ICR)ATF7 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATF7
EVEXATF7
GoPubMedATF7
iHOPATF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:52:46 CET 2018

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